Publications by authors named "Yaowen Xia"
Background: To identify the factors influencing pyrotinib-induced severe diarrhea and to establish a risk prediction nomogram model.
Methods: The clinical data of 226 patients received pyrotinib from two medical institutions from January 2019 to December 2023 were analysed retrospectively. A training set was made up of 167 patients from Hainan Cancer Hospital, and the external validation set was made up of 59 patients from Hainan West Central Hospital.
Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery.
Eur J Pharm Biopharm
April 2015
Article Synopsis
- The eye's unique structure limits how well medications can be absorbed, which is known as low bioavailability.
- Using mucoadhesive materials, like silk fibroin (SF), can enhance the effectiveness of eye drops.
- This study developed liposomes coated with SF for delivering ibuprofen, showing better drug release and cell compatibility compared to traditional methods, indicating a promising approach for ocular drug delivery.
Objective: To evaluate the prevalence of and risk factors for nonfatal overdose among heroin users in southwestern China.
Methods: In 2005, 731 heroin users in Sichuan Province, China were interviewed for overdose experiences in the past 12 months. Factors hypothesized to be associated with overdose were evaluated with logistic regression models.