Complexation Behavior and Clinical Assessment of Isomeric Calcium Ionophores of ETH 1001 in Polymeric Ion-Selective Membranes.

Calcium ions are crucial in numerous physiological processes, and their precise measurement is important for many clinical diagnostics and therapeutic interventions. Traditional detection methods, such as atomic absorption spectroscopy, cannot meet clinical requirements, as they measure total calcium instead of the clinically relevant ionized form (Ca). Ion-selective electrodes (ISEs) provide a convenient, accurate, and specific method for Ca determination.

Self-Powered Potentiometric Sensor with Relational Operation Function to Capture Concentration Excursions.

Self-powered potentiometric sensors spontaneously respond to activity changes of target species without the need for an external power source. Here, a self-powered potentiometric sensing approach is described that may store concentration perturbations that occur before the sensor readout through a combination of capacitors and diodes. Two channels, termed "more than" and "less than" operators, are utilized as memory modules in the sensor circuit to record positive and negative concentration excursions, respectively.

Self-Powered Potentiometric Sensor Based on a Passive Signal Amplifier with Electronic Paper Display.

Self-powered potentiometric sensors are attractive because of their simple operation, low cost, fast response, and ability to be integrated with electronic components. Self-powered potentiometric sensors that give a direct colorimetric output are especially interesting, because no power supply is needed, which dramatically reduces waste. Recently reported work from our group using an electronic paper display, however, exhibits limitations, because the visualization of small pH changes is difficult.

Distance-Based Self-Powered Signal Transduction of Ion-Selective Electrodes to an Electronic Paper Display Array.

In this article, we report on the first distance-based readout self-powered potentiometric sensor. The approach is considered more user-friendly for detection by the naked eye and is less prone to optical interferences compared with a direct observation of the pixel darkening. pH-selective electrodes were chosen as a model system to demonstrate the principle in which seven bar-shaped pixels connected in series on one e-paper share one common ground.

Self-Powered Signal Transduction of Ion-Selective Electrodes to an Electronic Paper Display.

Mobile integrated electrochemical sensors normally require a power supply for operation. Unfortunately, the practice of discarding batteries associated with these devices runs counter to our desire for a sustainable world. Self-powered sensing concepts that draw the energy directly from the measurement itself would overcome this limitation.

Direct Energy Transfer from a pH Glass Electrode to a Liquid Crystal Display.

Self-powered sensors are attractive because the lack of a dedicated battery makes them environmentally friendly and allows them to be more easily miniaturized. Unfortunately, the development of self-powered potentiometric sensors is challenging because only very limited energy can be harvested from this measurement principle. For the first time, the potential of a high impedance glass pH electrode (130 M Ω) is shown here to be directly read out optically.

Colorimetric and fluorescent turn-on detection of chloride ions with ionophore and BODIPY: Evaluation with nanospheres and cellulose paper.

Here, we present the optical detection of chloride ions with co-extraction based anion-selective optodes containing a BODIPY derivative (BDP-OH) and the ionophore In(OEP)Cl. Spectroscopic studies suggested that BDP-OH and In(OEP)Cl formed an adduct BDP-O-In(OEP), which was converted to BDP-OH and In(OEP)Cl upon increasing sample Cl concentration, and induced signal changes in both fluorescence and absorbance modes. The method was evaluated in polystyrene-graft-poly(ethylene oxide) (PS-PEO) nanospheres (ca.

Graphene Quantum Dots Integrated in Ionophore-Based Fluorescent Nanosensors for Na and K.

To enrich the recipes of ion-selective nanosensors, graphene quantum dots (GQDs) were integrated into ionophore-based fluorescent nanosensors with exquisite selectivity and high sensitivity for Na and K. The unique property of GQDs gave the nanosensors ultrasmall size (ca. 10 nm), high brightness, good biocompatibility, and potential pH sensing possibility.