Publications by authors named "Yaotan Li"
Background: Diabetic nephropathy (DN) is a major microvascular complication of diabetes and has become the leading cause of end-stage renal disease worldwide. A considerable number of DN patients have experienced irreversible end-stage renal disease progression due to the inability to diagnose the disease early. Therefore, reliable biomarkers that are helpful for early diagnosis and treatment are identified.
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- Autophagy is a crucial cellular process that involves breaking down and recycling components, and it has been found to significantly impact kidney diseases.
- A bibliometric analysis of 4,579 articles from 2000 to 2022 identified China and the U.S. as leading contributors, with a notable increase in publications and open-access journals being pivotal.
- Key research institutions include Nanjing Medical University, Osaka University, and the University of Pittsburgh, with major focuses on diabetic kidney diseases and acute/chronic kidney disease, while future trends may explore topics like sepsis and oxidative stress.
Background: Recently, several systematic reviews (SRs) and meta-analyses (MAs) of Tripterygium wilfordii polyglycoside (TWP) have reported significant benefits on diabetic kidney disease (DKD). However, the adoption of TWP for DKD remains uncommon. This study aimed to evaluate and summarize the current evidence on TWP for DKD.
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