Publications by authors named "Yaohui Guo"

Purpose: Tracheomalacia (TM) is commonly associated with esophageal atresia (EA) and compression by the brachiocephalic artery is a factor for TM. Previous research has focused on the lateral-to-anteroposterior tracheal diameter ratio (LAR). This study aimed to assess the LAR and postoperative outcomes of EA patients.

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Background: Multiple myeloma (MM) often causes renal tubular damage, such as the light chain cast nephropathy (LCCN) and the light chain proximal tubulopathy (LCPT). The excessive light chains deposited in the proximal and distal tubules usually manifest with different characteristics, leading to a rare coexistence of the two pathological conditions. Here we report a unique case of a patient with multiple myeloma (MM) who presented with acute kidney injury (AKI) due to dual conditions of λ light chain-restricted non-crystalline LCPT and LCCN.

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  • Biliary atresia (BA) leads to ongoing liver inflammation and fibrosis even after jaundice is cleared, prompting a study on the benefits of eicosapentaenoic acid (EPA) for post-treatment recovery.
  • The study involved BA patients who received EPA after a surgical procedure, comparing their outcomes with those who did not receive EPA over two years.
  • Results indicated that while EPA did not enhance jaundice clearance, it significantly reduced liver fibrosis progression in patients who were jaundice-free two years post-surgery.
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Background: Pediatric minimally invasive surgery requires advanced technical skills. Off-the-job training (OJT), especially when using disease-specific models, is an effective method of acquiring surgical skills. To achieve effective OJT, it is necessary to provide objective and appropriate skill assessment feedback to trainees.

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  • * Out of 97 patients, 29 were excluded, leaving 48 living with their native liver and 20 who received transplants after one year, with bile lake identified as the strongest risk factor for liver transplant.
  • * The findings suggest that bile lake can lead to serious complications, highlighting its significance as a risk factor for those with biliary atresia who maintain their native liver for a year post-surgery.
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  • The study assesses the effectiveness of thoracoscopic primary repair for esophageal atresia with tracheoesophageal fistula in newborns, specifically focusing on patients weighing less than 2000 g and those undergoing emergency surgery on their birth day.
  • A total of 43 patients were analyzed, revealing that surgical outcomes were similar regardless of weight, but those who had surgery at birth had a higher incidence of anastomotic leakage compared to those operated on after one day.
  • The findings suggest that while thoracoscopic primary repair is generally safe for low-weight newborns, caution is advised for those needing emergency surgery at 0 days due to the increased risk of complications.
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  • This study focused on creating a treatment plan for infants with congenital biliary dilatation diagnosed before birth, analyzing patient data from surgeries performed between 2013 and 2023.
  • It compared two groups of infants: those needing immediate surgery ("early group") and those who could wait ("scheduled group") while assessing various health indicators like blood test results and cyst size.
  • The findings revealed that infants with cysts larger than 30 mm at birth are at a higher risk of needing surgery early, suggesting the importance of close monitoring and guidance for their families.
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Purpose: The optimal surgical approach for recurrent congenital diaphragmatic hernia (CDH) remains controversial. We compared the surgical outcomes of a thoracoscopic approach versus an open abdominal approach for recurrent CDH after initial abdominal open repair.

Method: The subjects of this comparative study were patients who underwent open abdominal or thoracoscopic surgery for recurrent CDH following an initial open abdominal repair.

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Purpose: This study aimed to clarify the validity of robot-assisted surgery (RAS) for pediatric patients with congenital biliary dilatation (CBD).

Methods: We retrospectively compared RAS and laparoscopic surgery (LS) for pediatric CBD performed by the same certified surgeon between 2016 and 2022.

Results: We included 6 RAS and 12 LS cases in this study.

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Article Synopsis
  • Kluth's research highlights the need for preoperative imaging studies to determine the surgical approach for esophageal atresia/tracheoesophageal fistula (EA/TEF) due to its anatomical variations.
  • Two case reports of Japanese boys with type C EA/TEF are presented, both successfully treated using a cervical approach after contrast examinations identified the TEF and upper esophageal pouch location.
  • The findings conclude that routine use of contrast examinations is beneficial for planning surgeries in EA/TEF cases, leading to successful procedures with minimal complications.
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Purpose: This study aimed to evaluate the learning curve of thoracoscopic repair of tracheoesophageal fistula (TEF) by a single surgeon using a cumulative sum (CUSUM) analysis.

Methods: Prospective clinical data of consecutive Gross type-C TEF repairs performed by a pediatric surgeon from 2010 to 2020 were recorded. CUSUM charts for anastomosis and operating times were generated.

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Despite improving the survival after repair of esophageal atresia (EA), the morbidity of EA repair remains high. Specifically, tracheomalacia (TM) is one of the most frequent complications of EA repair. Continuous positive airway pressure is generally applied for the treatment of TM.

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Background: Congenital chylothorax (CCT) and postoperative chylothorax (POCT) are rare and difficult to treat. We report our treatment strategy and outcomes for chylothorax, including thoracoscopic surgery with indocyanine-green (ICG) near-infrared fluorescence lymphangiography.

Methods: A retrospective review of patients with CCT and POCT from 2014 to 2021 was performed.

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Hernioplasty for giant inguinal hernias can cause abdominal compartment syndrome (ACS) in adults but rarely does in infants. We encountered a case of a giant bilateral inguinal hernia in infancy complicated by ACS after hernioplasty. Silo placement a skin incision effectively treated ACS, after which the abdominal wall was safely closed.

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We report an extremely rare case of a right Bochdalek hernia with a sac, in which the retroperitoneal and intra-abdominal organs prolapsed into the thoracic cavity at the same time. The patient was a 7-month-old female with no comorbidities. She presented with cough and fever, and chest radiography revealed a right diaphragmatic hernia.

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Bile lake, of the postoperative complications after Kasai portoenterostomy (PE) for biliary atresia, causes cholangitis that may induce progressive fibrosis of the liver. Standard treatment for bile lakes has not yet been established, but there are reports that surgical internal intestinal drainage for bile lakes effectively prevents cholangitis and maintains jaundice-free status. In this case, insertion of the percutaneous transhepatic biliary drainage into the bile lake allowed continuous drainage of large volumes of bile juice.

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Purpose: Gastrointestinal bleeding (GIB) due to esophageal varices (EV) is one of the factors that negatively impact native liver survival of patients with biliary atresia (BA). Gastrointestinal fibroscopy (GIF) is usually used to determine the presence of EVs; however, it requires general anesthesia. The aim of this study is to search for markers in blood tests obtained during routine check-ups that can predict the development of GIB.

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Background/purpose: Congenital biliary dilatation (CBD) is a disease associated with pancreaticobiliary maljunction. The most frequent postoperative complication is intrahepatic stones, which are caused by hilar bile duct stenosis (HBDS).

Methods: We retrospectively reviewed the records of patients who underwent primary surgery for CBD between 2013 and 2021.

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Knowledge of band alignments and heterostructure formations is fundamental for a new generation of optoelectronics based on two-dimensional layered materials. Herein, band alignments and heterostructures of IVB-VIA monolayer MX (M = Zr, Hf; X = S, Se) and VIIB-VIA monolayer MX (M = Tc, Re; X = S, Se) are calculated by density functional theory with hybrid functionals. The results indicate that for monolayer MX, the valence bands mainly depend on the p state of the chalcogens and the conduction bands mainly depend on the d state of the transition metals.

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A scalable liquid exfoliation of layered BiS employing a mixed-solvent strategy was used for the fabrication of BiS nanosheets. We found that 10% deionized water in 90% isopropyl alcohol is the best mixed solvent for the efficient and effective exfoliation of layered BiS. These results are consistent with the absorbance spectra and enthalpy of mixing theory.

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Two methods were presented for the sensitive and selective determination of chitosan (CTS) with Congo red (CR) as probe based on resonance Rayleigh scattering (RRS) intensities in health products. In weakly acidic buffer solution, the binding of CTS to CR, could result in the enhancement of the RRS intensities. Moreover, after adding OP emulsifier (octyl-phenyl polyoxyethylene ether) to the system, the RRS intensities showed more significantly enhancement.

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Surface optical rectification was observed from the layered semiconductor molybdenum disulfide (MoS) crystal via terahertz (THz) time-domain surface emission spectroscopy under linearly polarized femtosecond laser excitation. The radiated THz amplitude of MoS has a linear dependence on ever-increasing pump fluence and thus quadratic with the pump electric field, which discriminates from the surface Dember field induced THz radiation in InAs and the transient photocurrent-induced THz generation in graphite. Theoretical analysis based on space symmetry of MoS crystal suggests that the underlying mechanism of THz radiation is surface optical rectification under the reflection configuration.

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MoS based photoelectrodes with different thickness have been fabricated by liquid phase exfoliation and vacuum filtration method. Absorption spectra clearly demonstrated two splitting absorption peaks due to the spin-orbit coupling and first principle calculation also indicate the spin-orbit coupling effect. These results combined with the SEM and TEM measurement suggests that the randomly stacked MoS films can maintain the properties of few-layered materials with good quality.

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Objective: Ganoderma lucidum was cultivated on non-medicinal parts of Salvia miltiorrhiza, Chrysanthemum morifolium, Ptatycodgn grandlfiorum, as all are Chinese traditional herbal medicines. We studied the changes of active ingredients and efficacies of the Ganoderma lucidum fruit bodies.

Methods: The agronomic characters, polysaccharide and terpene contents, acute toxicity and efficacy of Ganoderma lucidum grown on the non-medicinal part of the three materials were compared with that grown on the ordinary formula group (OF.

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