[The clinical significance of a new classification algorithm in Chinese DLBCL cases].

Objective: To investigate the clinicopathologic features, pathogenesis, diagnostic criteria and the relationship between different classification models and prognosis in Chinese patients with DLBCL, and try to look for the most appropriate classification model to predict clinical prognosis and therapeutic responses for Chinese patients with DLBCL.

Methods: 181 cases of Chinese DLBCLs diagnosed according to the WHO 2008 classification were collected. Standard two-step Envision method of immunohistochemical staining was used to assess the expressions of CD20, CD3ε, CD79a, CD10, Mum-1, Bcl-6, GCET-1, FOXP1 and Ki-67.

[Clinicopathologic analysis of nodal marginal zone B cell lymphoma].

Objective: To investigate the clinicopathologic features of primary nodal marginal zone B-cell lymphoma (NMZL).

Methods: Hematoxylin-Eosin staining and immunohistochemistry were used to evaluate the histological and immunophenotypic characteristics of lymph node (LN) tissue in 22 NMZL cases. Additionally, interphase fluorescence in-situ hybridization (FISH) was carried out to detect the presence of t(11;18) (q21;q21)/API2-MALT1 and/or t(14;18)(q32;q21)/IGH-MALT1 in 9 cases.

[A histopathological study on Influenza A H1N1 infection in humans].

Objective: To find histopathological changes on major organs of Influenza A H1N1-infected patients and its relationship to clinical symptoms.

Methods: The autopsies were performed following conventional protocols and strict safety procedures. Tissue samples from all major organs of three cases were collected and fixed in 4% formalin.

[Pathology of enterovirus 71 infection: an autopsy study of 5 cases].

Objective: To study the clinicopathologic features of fatal enterovirus 71 (EV71) infection.

Methods: Autopsy was performed in 5 neonates died of EV71 infection. Tissue samples from major organs were collected, formalin-fixed and examined under light microscopy.