Objective: To identify specific protein markers for renal cell carcinoma detection and diagnosis, as well as develop new potential therapeutic targets of the disease.
Methods: We used two-dimensional difference in-gel electrophoresis (2-D DIGE) technique conjunction with mass spectrometry (MS) for the identification of significant differentially expressed proteins between 15cases of paired clear cell renal cell carcinoma (ccRCC) and adjacent normal renal tissues. The protein spots were considered as differentially expressed if a 1.
Objective: To assess the therapeutic effect of acupuncture combining standard swallowing training for patients with dysphagia after stroke.
Methods: A total of 105 consecutively admitted patients with post-stroke dysphagia in the Affiliated Hospital of Gansu University of Chinese Medicine were included: 50 patients from the Department of Neurology and Rehabilitation received standard swallowing training and acupuncture treatment (acupuncture group); 55 patients from the Department of Neurology received standard swallowing training only (control group). Participants in both groups received 5-day therapy per week for a 4-week period.
Objective: To investigate effects of Zibu Shenjing Fang (see text) on growth and development of the mouse with insufficiency ofkidney-essence and the mechanism.
Methods: Total 50 mice were randomly divided into a normal group, a model group, a Jingui Shenqi Wan (see text) group, a Zibu Shenjing Fang high dose group and a Zibu Shenjing Fang low dose group, 10 mice in each group. The kidney-essence insufficiency mouse model was established by use of threat-injuring the kidney combined with over-fatigue.
Nan Fang Yi Ke Da Xue Xue Bao
July 2009
Objective: To compare the therapeutic effect of 3 minimally invasive approaches for ureteral calculi removal and analyze their respective advantages and limitations.
Methods: A retrospective analysis was conducted in 326 patients receiving extracorporeal shock wave lithotripsy (ESWL), ureteroscopic lithotripsy (URL) or percutaneous nephrolithotripsy (PCNL) for ureteral calculi. The clinical data including the stone-free rate and complications were analyzed.
Objective: To explore the expression of hypoxia inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in renal cell carcinoma (RCC) and their relationship.
Methods: The expression of HIF-1alphaand VEGF was examined in 42 patients with renal cell carcinoma by SABC methods of immunohistochemistry.
Results: The positivity rate of HIF-1alpha was 57.
Di Yi Jun Yi Da Xue Xue Bao
March 2005
Objective: To evaluate the clinical effects of nephron-sparing surgery in patients with early-stage small renal cell carcinoma.
Methods: Nephron-sparing surgery was performed in 21 patients with renal cell carcinoma including 1 with solitary kidney, 3 with unilateral tumor and contralateral renal compromise, and 17 with unilateral tumor and normal contralateral kidney. The diameter of the tumors ranged from 1.