Hair Follicle Transit-Amplifying Cells Phagocytose Dead Cells after Radiotherapeutic and Chemotherapeutic Injuries for Timely Regeneration.

Efficient clearance of dead cells is critical for tissue regeneration after injuries. How dead cells are removed from the skin after radiotherapy and chemotherapy is unclear. In this study, we found that radiotherapeutic and chemotherapeutic damage induced extensive apoptosis of highly proliferative transit-amplifying cells in hair follicles.

Waterline digital elevation model development to quantify inundation duration and coastal protection of tidal wetlands.

Coastal tidal wetlands are sufficiently acknowledged for the supplied vital ecosystem functions, including flood protection and biological conservation. Measuring and estimating reliable topographic data is essential for quantifying mangrove habitat quality. This study proposes a novel methodology for quickly constructing a digital elevation model (DEM) with an instantaneous waterline combined with tidal level records.

Nature-based solutions on floodplain restoration with coupled propagule dispersal simulation and stepping-stone approach to predict mangrove encroachment in an estuary.

The mangrove ecosystem is significantly affected by human activities, climate change, and rising sea level. The propagules of mangroves dispersal with tide and river currents that extend upstream habitats are why mangroves are the dominant species in the tidal area. Bridging critical knowledge gaps can help to create restoration plans for mangrove extension.

Methylomics of nitroxidative stress on precancerous cells reveals DNA methylation alteration at the transition from to invasive cervical cancer.

Epigenetic dysregulation is important in cervical cancer development, but the underlying mechanism is largely unknown. Increasing evidence indicates that DNA methylation is sensitive to changes in microenvironmental factors, such as nitric oxide (NO) in the chronic inflammatory cervix. However, the epigenomic effects of NO in cancer have not been investigated.

Synthesis and Properties of Carbon Nanotube-Grafted Silica Nanoarchitecture-Reinforced Poly(Lactic Acid).

A novel nanoarchitecture-reinforced poly(lactic acid) (PLA) nanocomposite was prepared using multi-walled carbon nanotube (MWCNT)-grafted silica nanohybrids as reinforcements. MWCNT-grafted silica nanohybrids were synthesized by the generation of silica nanoparticles on the MWCNT surface through the sol-gel technique. This synthetic method involves organo-modified MWCNTs that are dispersed in tetrahydrofuran, which incorporates tetraethoxysilane that undergoes an ultrasonic sol-gel process.

Constructing 3D heterogeneous hydrogels from electrically manipulated prepolymer droplets and crosslinked microgels.

Formation of multifunctional, heterogeneous, and encoded hydrogel building blocks, or microgels, by crosslinking and assembly of microgels are two essential steps in establishing hierarchical, complicated, and three-dimensional (3D) hydrogel architectures that recapitulate natural and biological structures or originate new materials by design. However, for the variety of the hydrogel materials crosslinked differently and for the varied scales of microgels and architectures, the formation and assembly processes are usually performed separately, which increases the manufacturing complexity of designed hydrogel materials. We show the construction of hydrogel architectures through programmable formation and assembly on an electromicrofluidic platform, adopting two reciprocal electric manipulations (electrowetting and dielectrophoresis) to manipulate varied objects (i) in multiple phases, including prepolymer liquid droplets and crosslinked microgels, (ii) on a wide range of scales from micrometer functional particles or cells to millimeter-assembled hydrogel architectures, and (iii) with diverse properties, such as conductive and dielectric droplets that are photocrosslinkable, chemically crosslinkable, or thermally crosslinkable.

Reconstructed bone chip detachment is a risk factor for sinusitis after transsphenoidal surgery.

Objectives/hypothesis: Sphenoid sinusitis is a complication associated with endoscopic transsphenoidal pituitary surgery. Studies that address the relationship between methods of sellar defect reconstruction and postoperative sinusitis are rare. The purpose of this study was to investigate the incidence, the possible risk factors, and the causative pathogens of sphenoid sinusitis after endoscopic transsphenoidal pituitary surgery.

Encapsulated droplets with metered and removable oil shells by electrowetting and dielectrophoresis.

A water-core and oil-shell encapsulated droplet exhibits several advantages including enhanced fluidic manipulation, reduced biofouling, decreased evaporation, and simplified device packaging. However, obtaining the encapsulated droplet with an adjustable water-to-oil volume ratio and a further removable oil shell is not possible by reported techniques using manual pipetting or droplet splitting. We report a parallel-plate device capable of generation, encapsulation, rinsing, and emersion of water and/or oil droplets to achieve three major aims.

Hand surface area estimation formula using 3D anthropometry.

Hand surface area is an important reference in occupational hygiene and many other applications. This study derives a formula for the palm surface area (PSA) and hand surface area (HSA) based on three-dimensional (3D) scan data. Two-hundred and seventy subjects, 135 males and 135 females, were recruited for this study.

Determination of hand surface area as a percentage of body surface area by 3D anthropometry.

This study investigates the hand surface area (HSA) and palm surface area (PSA) percentages of body surface area (BSA). The HSA and PSA of 135 men and 135 women were measured by scanner and incorporated into an existing BSA database to derive %HSA/BSA and %PSA/BSA using five stature heights and three body weights in accordance with population distribution. Allowing for various degrees of specificity, the mean %HSA/BSA and mean %PSA/BSA were found to be 2.