Publications by authors named "Yao-Ping Shi"

Context: To date there is no study on the feasibility of radiofrequency ablation (RFA) for papillary thyroid microcarcinomas (PTMCs) with BRAF V600E mutation.

Objective: This study was designed to evaluate the efficiency, safety, and prognosis of ultrasound (US)-guided percutaneous RFA for unifocal PTMCs with BRAF V600E mutation.

Materials And Methods: Sixty patients with 60 unifocal BRAF V600E mutation-positive PTMCs who received US-guided RFA between January 2020 and December 2021 were retrospectively analyzed.

View Article and Find Full Text PDF
Article Synopsis
  • This study examines the effectiveness and safety of radiofrequency ablation (RFA) in treating large benign solid thyroid nodules, focusing on outcomes like volume reduction, complications, and thyroid function.
  • A total of 24 patients with 25 nodules were treated with either single or sequential RFA between 2015 and 2019, with results showing significant volume reduction six months post-procedure, and no major complications.
  • Overall, RFA proved to be a safe and effective method for alleviating symptoms caused by large thyroid nodules, improving both compression symptoms and cosmetic appearance without leading to significant recurrence.
View Article and Find Full Text PDF

Clinical advancement of the bioartificial liver is hampered by the lack of expandable human hepatocytes and appropriate bioreactors and carriers to encourage hepatic cells to function during extracorporeal circulation. We have recently developed an efficient approach for derivation of expandable liver progenitor-like cells from human primary hepatocytes (HepLPCs). Here, we generated immortalized and functionally enhanced HepLPCs by introducing , a hepatocyte nuclear factor that enables potentially complete hepatic function.

View Article and Find Full Text PDF

Living tumors are of great scientific value for clinical medicine and basic research, especially for drug testing. An increasing number of drug tests fail due to the use of imperfect models. The aim of the present study was to develop a novel method combining vitrification‑based cryopreservation of tumor biopsies and precision‑cut slice cultivation for the assessment of anticancer drug responses.

View Article and Find Full Text PDF

Introduction: To evaluate the feasibility and safety of ultrasound-guided iodine-125 interstitial implants for high-risk hepatocellular carcinoma.

Methods: From October, 2016, to August, 2018, 49 patients suffering from a total of 66 hepatocellular carcinoma lesions were treated with ultrasound-guided iodine-125 interstitial implantation. Treatment planning system was applied to make preoperative plan.

View Article and Find Full Text PDF