A phenazine-imidazole based ratiometric fluorescent probe for Cd ions and its application in imaging.

A new phenazine-imidazole based Schiff base (PIS) fluorescent probe has been developed for the ratiometric detection of Cd ions in aqueous media at physiological pH. PIS upon binding with Cd ions shows red shifted fluorescence and thereby, permits ratiometric detection of Cd(II) ions. A detection limit down to 2.

New colorimetric and fluorometric chemosensor for selective Hg sensing in a near-perfect aqueous solution and bio-imaging.

We report a new 7-nitrobenzo-2-oxa-1, 3-diazolyl (NBD)-based chemosensor containing a piperazine derivative, NBDP, for detection of mercury ions in almost 100% aqueous medium. The chemosensor shows sensing exclusively toward Hg with a switch-on fluorescence response at 543 nm, which could be attributed to the blocking of PET (photo-induced electron transfer) process upon complexation with mercury ions. The molar ratio of Hg(Ⅱ) to NBDP in the complex is 1:1 based on the Job's plot and HRMS studies.

Gastrodin protects retinal ganglion cells through inhibiting microglial-mediated neuroinflammation in an acute ocular hypertension model.

Aim: To investigate the neuroprotective effect of gastrodin on retinal ganglion cells (RGCs) in an acute ocular hypertension (AOH) rat model and to identify its possible mechanism.

Methods: AOH rat model was performed in a randomly selected eye by anterior chamber perfusion and either received an intraperitoneal injection with various concentrations of gastrodin or normal saline. After 2wk, the rats were sacrificed.

Aqueous proinflammatory cytokines in acute primary angle-closure eyes.

Aim: To evaluate changes of proinflammatory cytokines in aqueous humor of patients with acute primary angle-closure (APAC) and age-related cataracts.

Methods: Twenty eyes of 20 APAC patients and 15 eyes of 15 age-related cataract patients were included in this cross-sectional study. Aqueous humor samples were collected prospectively.

[Study on antidepressant components of sucrose ester from Polygala tenuifolia].

Objective: To investigate the antidepressant components of Polygala tenuifolia.

Method: The chromatographic method was used to isolate and purify the chemical constituents, their structures were identified by spectral analysis, MTT method was applied to investigate their cytotoxic activities.

Result: Nine compounds were isolated from the roots of P.

A spectroscopic study of the 3(1) pi g Rydberg state of 7Li2.

With pulsed optical-optical double resonance (OODR) fluorescence excitation spectroscopy Rydberg states of 7Li2 in the energy region of 35,500-38,000 cm-1 were studied and 146 transitions into the 3(1) pi g state of 7Li2 were measured. They were assigned to 10 vibrational levels of the 3(1) pi g state. A new set of Dunham constants, RKR potential curve, and Franck-Condon factors for the transitions form the A 1 sigma u+ state are derived.