Publications by authors named "Yao-Kun Zhang"
Article Synopsis
- Mutations in nucleic acids or proteins can impact how well proteins bind to nucleic acids, but research has mostly focused on protein mutations, leaving nucleic acid mutations underexplored.
- A new algorithm called PNBACE has been developed to assess the effects of both DNA and protein mutations on binding affinity, using novel energy-based features to enhance prediction accuracy.
- PNBACE outperformed existing methods in predicting the impact of single and multiple mutations on binding affinities, improving our understanding of protein-nucleic acid interactions.
Huan Jing Ke Xue
June 2018
Article Synopsis
- - The study focused on creating zirconium alginate/poly(-isopropyl acrylamide) hydrogel beads (ZA/PNIPAM) to remove phosphates from water, using a specific method for crosslinking and polymerization.
- - Research showed that the phosphate removal efficiency was best at a pH of 2, depending on factors like adsorbent dose, initial phosphate concentration, and the presence of other ions, with sulfate having a negative effect compared to chloride and nitrate.
- - The adsorption process was analyzed using various models, revealing that it mainly involved surface adsorption and internal diffusion, with mechanisms including electrostatic attraction and ligand exchange, while showing good reusability after multiple cycles.
