The genus Bhat (Hymenoptera, Braconidae, Alysiinae) newly recorded from China.

Background: Alysiinae Leach is a species-rich subfamily in Braconidae, of which several species play an important role in biological control. The monotypic genus Bhat, 1980 was discovered in Tibet and Yunnan provinces for the first time, representing the first record of the genus Bhat, 1980 (Braconidae, Alysiinae) in China.

New Information: The rare genus Bhat, 1980 (Braconidae, Alysiinae) and its only known species, Bhat, 1980, are newly recorded from China.

The prognostic value and immune landscape of a cuproptosis-related lncRNA signature in head and neck squamous cell carcinoma.

Cuproptosis has been recognized as a novel regulatory cell death, which has been confirmed to promote the occurrence and development of tumors. However, whether cuproptosis-related lncRNA has an impact on the prognosis of squamous cell carcinoma of the head and neck (HNSCC) is still unclear. In total, 501 HNSCC tumor samples and 44 normal were downloaded from the TCGA database.

Purified Phlorizin from (Wall.) Decne by HSCCC, Compared with Whole Extract, Phlorizin and Non-Phlorizin Fragment Ameliorate Obesity, Insulin Resistance, and Improves Intestinal Barrier Function in High-Fat-Diet-Fed Mice.

Natural products generally contain complex and multiple bioactive compounds that are responsible for the effects on health through complicated synergistic and/or suppressive actions. As an important raw material of local ethnic minority tea, ethnomedicines and food supplements in southwestern areas of China, (Wall.) Decne (DID) mainly consists of phlorizin (PHZ), which is the main active component.

Sonic hedgehog signaling in spinal cord contributes to morphine-induced hyperalgesia and tolerance through upregulating brain-derived neurotrophic factor expression.

Purpose: Preventing opioid-induced hyperalgesia and tolerance continues to be a major clinical challenge, and the underlying mechanisms of hyperalgesia and tolerance remain elusive. Here, we investigated the role of sonic hedgehog (Shh) signaling in opioid-induced hyperalgesia and tolerance.

Methods: Shh signaling expression, behavioral changes, and neurochemical alterations induced by morphine were analyzed in male adult CD-1 mice with repeated administration of morphine.

IL-18 Contributes to Bone Cancer Pain by Regulating Glia Cells and Neuron Interaction.

Unlabelled: Glial cell hyperactivity has been proposed to be responsible for chronic pain, however, the mechanisms remain unclear. Interleukin (IL)-18, released from glial cells, has been reported to be involved in neuropathic pain. In this study, we investigated the role of IL-18 in bone cancer pain.

[The experimental study on porous calcium phosphate cement with bone marrow stromal cells for bone tissue engineering].

Objective: To observe the biocompatibility of new biomaterials porous calcium phosphate (CPC) and ectopic bone formation of CPC with bone marrow stromal cells (BMSCs).

Methods: The BMSCs were cultured from Beagle dog and combined with the porous CPC with the best concentration after transfect green fluorescent protein (GFP). The adhesion and growth of BMSCs on CPC were observed under inversion, fluorescence and scanning electron microscopy.

PPLook: an automated data mining tool for protein-protein interaction.

Background: Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of interactions among proteins. There is a lack of tools to extract PPI, visualize and classify the results.

[Expression of cyclooxygenase-2 and 15-prostaglandin dehydrogenase of placenta and fetal membranes in patients of preterm labor].

Objective: To investigate the effect of cyclooxygenase 2 (COX-2) and 15-prostaglandin dehydrogenase (15-PGDH) on preterm labor.

Methods: The expressions and localizations of COX-2 and 15-PGDH in placentas and fetal membranes were examined by immunohistochemical (IH) two-step assay (IH scores were expressed as the sum of the percentage of immunoreactivity and the stained degree of cells), respectively. The samples were obtained from 14 preterm delivery (PL), 18 term in labor (TL) and 17 term not in labor (control group).