Publications by authors named "Yao-Jing Han"
Article Synopsis
- Depression cases among adolescents are rising, prompting research into the biochemical factors affecting cognitive function, particularly focusing on areas of the brain like the anterior cingulate gyrus and thalamus.
- The study utilized proton magnetic resonance spectroscopy (H-MRS) to analyze biochemical metabolites in adolescents with depression and a control group, measuring ratios such as N-acetylaspartate (NAA)/Creatine (Cr) and others.
- Results indicated that adolescents with depression had higher depression scores and lower memory function, alongside significant differences in certain metabolite ratios compared to healthy peers, suggesting a biochemical basis for the cognitive impacts of depression.
Objective: To explore the efficacy and safety of tandospirone for adolescents with anxiety disorder.
Methods: In this multicenter open-label 12-week study, a total of 169 adolescents met the criteria of DSM-IV for anxiety disorder were treated with flexible dose of tandospirone. The effects and safety of treatment were assessed by the Hamilton anxiety scale (HAMA), state-trait anxiety inventory (STAI), clinical global impression (CGI) and side effects at baseline and Weeks 2, 4, 8 and 12.