Synopsis of recent research by authors named "Yao-Hui Gao"
- Yao-Hui Gao's research primarily focuses on the biosynthesis of natural products, particularly antibiotics and enzymatic processes that facilitate key chemical reactions, such as demethylation and C-C bond cleavage in various bioactive compounds.
- Recent studies include the exploration of enfumafungin-type antibiotics, showcasing their significant antifungal properties and unique biosynthetic mechanisms, as well as advancing knowledge on the biosynthesis of acetylenic bonds in natural products like meroterpenoids.
- In addition to natural product biosynthesis, Gao's work also investigates molecular mechanisms in cancer biology, specifically related to renal cell carcinoma and the interactive roles of the VHL gene and hypoxia-inducible factors in drug sensitivity and disease pathology.