Publications by authors named "Yao-Huan Sun"
Article Synopsis
- The study looked at how having a buddy (pair-housing) can help mice feel less depressed after a stroke by improving the gut and brain connection.
- Mice that were pair-housed showed less anxiety and depression and had healthier gut bacteria compared to those that weren’t.
- However, when some pair-housed mice drank antibiotic water, the benefits were lost, showing that healthy gut bacteria are important for feeling better after depression.
The beneficial effect of social interaction in mitigating the incidence of post-stroke depression (PSD) and ameliorating depressive symptoms has been consistently demonstrated through preclinical and clinical studies. However, the underlying relationship with oxytocin requires further investigation. In light of this, the present study aimed to explore the protective effect of pair housing on the development of PSD and the potential relationship with oxytocin receptors.
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