Spatial and temporal distribution of arsenic concentration in rural drinking water and health risk assessment in Northern China from 2013 to 2022: a case study of Inner Mongolia Autonomous Region.

Background: By monitoring arsenic levels in rural drinking water in Inner Mongolia Autonomous Region from 2013 to 2022 and evaluating their health risks, this study provides a basis for further developing strategies to promote public health.

Methods: One stable centralized water supply point was randomly selected in each township of Inner Mongolia Autonomous Region. One finished water sample and 1-3 tap water samples were collected at each supply point.

[B1a and b1b evolutionary branch of coxsackie virus A16 co-prevailed in Inner Mongolia Autonomous Region].

To study on the molecular evolution of Coxsackie virus A16 (CVA16)isolated from clinical speci-mens of Hand, foot and mouth Disease( HFMD) patients in Inner Mongolia in 2010. A total of 921 clinical specimens including stools, throat swabs and vesicle fluids were collected from 888 HFMD patients in out-patient service in Inner Mongolia and viral isolation was then performed, the positive viral isolates were identified by using the real-time PCR method detecting CVA16. A total of 50 CVA16 isolates were selected from the patients presenting mild symptoms, severe symptoms and the death patients randomly, and the VP1 coding regions of representative CVA16 isolates were amplified and sequenced.

[NSP5/NSP6 of rotavirus strain TB-Chen and preliminary genotyping analysis].

Strain TB-Chen is a group A rotavirus (RV) isolated from a Chinese infant suffering from gastroenteritis in hospital. The NSP5 and NSP6 of strain TB-Chen are encoded by the 10th gene segment (816bp in whole length) of the viral genome. The results obtained in this study showed that the NSP5 was encoded in the first open-reading-frame (ORF) of the gene segment (from 22bp to 624bp), and NSP6 was encoded in the second ORF (from 80bp to 355bp).