Hydrogen inhibition of wet AlLi alloy dust collector systems using a composite green biopolymer inhibitor based on chitosan/sodium alginate: Experimental and theoretical studies.

Aluminum‑lithium (AlLi) alloy polishing and grinding processes in wet dust collector systems could cause hydrogen fire and explosion. From the fundamental perspective of preventing hydrogen explosions, a safe, nontoxic, and sustainable modified green hydrogen inhibitor based on chitosan (CS) and sodium alginate (SA) was developed in this study and was used as a hydrogen evolution inhibitor for the processing of waste dust from AlLi alloys. The structure and elemental distribution of the synthesized material were characterized through characterization experiments.

The hypoglycemic effect of enzymatic modified dietary fiber from bamboo shoot on type 2 diabetes rats.

Bamboo shoot is a healthy food rich in dietary fiber (DF). However, its highly insoluble DF and fibrous texture limit its application in industrially processed foods. To achieve industrial processing of bamboo shoot, cellulase was used to improve the physical characteristics of bamboo shoot DF in this study.

Effect of jujube orchard abandonment time on soil properties and enzyme activities at soil profile in the Loess Plateau.

In the Loess Plateau, the impact of abandoned farmland on soil properties and enzyme activity, along with its temporal variations and potential driving factors, remains a mystery. This study was designed to systematically and comprehensively examine the variations in soil enzyme activities, particle size distribution, and stability of soil aggregates at different stages of ecological recovery in the Loess Plateau. Our findings reveal a nuanced temporal pattern: with the progression of cropland abandonment, there is a notable decrease in soil bulk density.

Lysosomal iron accumulation and subsequent lysosomes-mitochondria iron transmission mediate PFOS-induced hepatocyte ferroptosis.

Perfluorooctane sulfonate (PFOS) is known as a persistent organic pollutant. A significant correlation between PFOS and liver ferroptosis has been unveiled, but the precise mechanism needs to be elucidated. In prior research, we found that PFOS treatment provoked mitochondrial iron overload.

Four new phenylpropanoid glycosides from the leaves of and their neuroprotective activities.

Four previously unreported phenylpropanoid glycosides (-), together with four known analogues (-), were isolated from the leaves of . The structures of these new compounds were elucidated based on spectroscopic analysis (HR-ESI-MS, NMR, IR, UV) and chemical methods. In addition, the neuroprotective activities of all the isolates were evaluated by measuring their cell viability in HO-induced OLN-93 cell injury model.

Dye-doped cellulose nanocrystals as novel dusting powders for visualizing latent fingerprints.

Powder-dusting method based on the visual contrast between the background surface and powder-covered ridges of a fingerprint is widely used to develop the invisible latent fingerprints (LFPs) left at crime scenes. Recently, the development of nano-sized powders with excellent optical performances has been extensively explored. In this work, we employed environmentally friendly and low-toxicity cellulose nanocrystals as the novel support.

Tumor hypoxia in immune infiltration and prognosis of bladder cancer.

Background: Bladder cancer (BC) is the sixth most common cancer and the ninth leading cause of cancer death among men in the world. Previous studies have shown that tumor hypoxia plays an important role in the occurrence and development of BC, but the role of tumor hypoxia in the prognosis and immune infiltration of BC remains unclear. Our aim was to perform a bioinformatics analysis combined with a clinical analysis to explore the roles of hypoxia in BC.

Combined retinal massage and autologous blood covering for persistent macular holes after vitrectomy in high myopia.

Purpose: To evaluate the efficacy of retinal massage combined with autologous blood covering in the treatment of persistent macular holes following vitrectomy in eyes with high myopia.

Settings And Design: Retrospective, consecutive case series in a tertiary eye center.

Methods: A total of 12 highly myopic eyes with persistent macular holes after vitrectomy and internal limiting membrane peeling received combined retinal massage, air/fluid exchange, autologous blood covering, and gas/silicone oil tamponade.

The role of BUD31 in clear cell renal cell carcinoma: prognostic significance, alternative splicing, and tumor immune environment.

BUD31, a splicing factor, is linked to various cancers. This study examines BUD31's expression, prognostic value, mutation profile, genomic instability, tumor immune environment, and role in clear cell renal cell carcinoma (ccRCC), focusing on cell cycle regulation via alternative splicing. BUD31 expression was analyzed using TCGA and GTEx databases across 33 cancers.

Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display.

Macrocyclic peptides are promising scaffolds for the covalent ligand discovery. However, platforms enabling the direct identification of covalent macrocyclic ligands in a high-throughput manner are limited. In this study, we present an mRNA display platform allowing selection of covalent macrocyclic inhibitors using 1,3-dibromoacetone-vinyl sulfone (DBA-VS).

Paired organoids from primary gastric cancer and lymphatic metastasis are useful for personalized medicine.

Background: Organoids are approved by the US FDA as an alternative to animal experiments to guide drug development and for sensitivity screening. Stable organoids models of gastric cancer are desirable for personalized medicine and drug screening.

Methods: Tumor tissues from a primary cancer of the stomach and metastatic cancer of the lymph node were collected for 3D culture.

Heterodinuclear AuNi(CO) ( = 2-3) Complexes Featuring an Anionic Au as a Donor Ligand for Ni(CO).

The gas-phase heterodinuclear gold-nickel carbonyl AuNi(CO) ( = 2-3) anion complexes were mass-selected and studied by using photoelectron velocity-map imaging spectroscopy in combination with quantum-chemical calculations, which can establish both the geometries and electronic structures of these anions. These complexes are all confirmed to be singlet ground states with one gold atom bonded at the central nickel atom of the Ni(CO) moieties. Further bonding analyses indicate that unlike the alkali-metals as covalently bonded ligands to form the electron-sharing alkali-metal-nickel bonding in the alkali-metal-nickel carbonyl anionic complexes, the Au atom in the AuNi(CO) complexes serves as a datively bound ligand for Ni(CO) to form gold-to-nickel dative bonding.

Differential Capillary and Large Vessel Analysis Improves OCTA Classification of Diabetic Retinopathy.

Purpose: This study aimed to investigate the impact of distinctive capillary-large vessel (CLV) analysis in optical coherence tomography angiography (OCTA) on the classification performance of diabetic retinopathy (DR).

Methods: This multicenter study analyzed 212 OCTA images from 146 patients, including 28 controls, 36 diabetic patients without DR (NoDR), 31 with mild non-proliferative DR (NPDR), 28 with moderate NPDR, and 23 with severe NPDR. Quantitative features were derived from the whole image as well as the parafovea and perifovea regions.

DNA Origami-Constructed Nanotapes for Sunitinib Adsorption and Inhibition of Renal Clear Carcinoma Cells.

Sunitinib (SUN) is a first-line drug for the treatment of renal clear carcinoma cells by targeting receptor tyrosine kinases (RTK) on the cell membrane. However, the effective delivery of SUN to the cell membrane remains a significant challenge. In this study, we fabricated precisely structured DNA nanotapes with strong surface SUN adhesion, enabling RTK inhibition of renal clear carcinoma cells.

From Novice to Mastery: Learning Curve and Efficacy Analysis of Short-Term Spinal Cord Stimulation for Diabetic Foot Ulcers.

Background: To analyze the learning curve of novices in mastering short-term Spinal cord stimulation (st-SCS) for diabetic foot, evaluating the efficacy, safety, and difficulty of this technique.

Methods: A retrospective review of diabetic foot patients treated with st-SCS at our hospital was conducted. All procedures were performed by the same physician and patients were sequentially numbered according to the order of surgery.

Methane-dependent denitrification by Methylomirabilis: an indirect nitrous oxide sink?

Methane-dependent complete denitrification primarily involves nitrate reduction to nitrite by ANME-2d archaea and nitrite reduction to dinitrogen by Methylomirabilis bacteria. 'Candidatus Methylomirabilis sinica' integrates the divisional labor. Physiological traits of this bacterium potentially enable the simultaneous reduction of NO and CH emissions.

A Transcriptomic Analysis of Bottle Gourd-Type Rootstock Roots Identifies Novel Transcription Factors Responsive to Low Root Zone Temperature Stress.

The bottle gourd [ (Molina) Standl.] is often utilized as a rootstock for watermelon grafting. This practice effectively mitigates the challenges associated with continuous cropping obstacles in watermelon cultivation.