XGBoost-based nomogram for predicting lymph node metastasis in endometrial carcinoma.

This study aims to construct and optimize risk prediction models for lymph node metastasis (LNM) in endometrial carcinoma (EC) patients, thus improving the identification of patients at high risk of LNM and further providing accurate support for clinical decision-making. This retrospective analysis included 541 cases of EC treated at The First Affiliated Hospital, Jinan University between January 2017 and January 2022. Various clinical and pathological variables were incorporated, including age, body mass index (BMI), pathological grading, myometrial invasion, lymphovascular space invasion (LVSI), estrogen receptor (ER) and progesterone receptor (PR) levels, and tumor size.

Evaluation of five questionnaires for obstructive sleep apnea screening in the elderly.

Obstructive sleep apnea (OSA) often leads to complications in the elderly. This study compares the usefulness of five screening tools for OSA in elderly patients. Data from elderly patients diagnosed with OSA, collected from the Sleep Medicine Center of the First Affiliated Hospital of Guangzhou Medical University from January 2012 to June 2017, is analyzed.

Prediction of Potential Habitat Distributions and Climate Change Impacts on the Rare Species (Magnoliaceae) in China Based on MaxEnt.

Changes in species' habitats provide important insights into the effects of climate change. , a critically endangered species endemic to karst ecosystems, has a highly restricted distribution and is a key biological resource. Despite its ecological importance, the factors influencing its habitat suitability and distribution remain poorly understood.

The Geometric Series Hypothesis of Leaf Area Distribution and Its Link to the Calculation of the Total Leaf Area per Shoot of 'Aureostriatus'.

Total leaf area per shoot () can reflect the photosynthetic capacity of a shoot. A prior study hypothesized that is proportional to the product of the sum of the individual leaf widths per shoot () and the maximum individual leaf length per shoot (), referred to as the Montgomery-Koyama-Smith equation (MKSE). However, empirical evidence does not support such a proportional relationship hypothesis, as was found to allometrically scale with , i.

Mitochondrial genome structural variants and candidate cytoplasmic male sterility-related gene in sugarcane.

Background: Sugarcane is a crucial crop for both sugar and bioethanol production. The nobilization breeding and utilization of wild germplasm have significantly enhanced its productivity. However, the pollen sterility in Saccharum officinarum restricts its role to being a female parent in crosses with Saccharum spontaneum during nobilization breeding, resulting in a narrow genetic basis for modern sugarcane cultivars.

Overlooked and underpowered: a meta-research addressing sample size in radiomics prediction models for binary outcomes.

Objectives: To investigate how studies determine the sample size when developing radiomics prediction models for binary outcomes, and whether the sample size meets the estimates obtained by using established criteria.

Methods: We identified radiomics studies that were published from 01 January 2023 to 31 December 2023 in seven leading peer-reviewed radiological journals. We reviewed the sample size justification methods, and actual sample size used.

Bio-inspired porous adsorbents with lotus-leaf-like hierarchical structures and mussel adhesive surfaces for high-capacity removal of toxic dyes.

Basic dyes are highly toxic and have adverse effects on humans such as accelerated heart rate, shock, cyanosis, and tissue necrosis upon ingestion or skin contact. Efficient removal of basic dye pollutants from wastewater is therefore essential for the protection of the environment and human health. Biomolecules exhibit excellent dye removal performance in terms of removal capacity, selectivity, and rate.

A class of n-D Hamiltonian conservative chaotic systems with three-terminal memristor: Modeling, dynamical analysis, and FPGA implementation.

Memristors are commonly used to introduce various chaotic systems and can be used to enhance their chaotic characteristics. However, due to the strict construction conditions of Hamiltonian systems, there has been limited research on the development of memristive Hamiltonian conservative chaotic systems (MHCCSs). In this work, a method for constructing three-terminal memristors is proposed, and the three-terminal memristors are incorporated into the Hamiltonian system, resulting in the development of a class of n-D MHCCS.

Efficacy analysis of pancreatic duct stenting in treating severe acute pancreatitis: a retrospective study.

Background: This study aims to evaluate the clinical efficacy of pancreatic duct stenting in the treatment of SAP, providing reference for clinical diagnosis and treatment.

Methods: A retrospective analysis was conducted on clinical data from patients with SAP admitted to the General Hospital of Ningxia Medical University from June 1, 2019 to December 31, 2022. A total of 51 patients were included (33 males, 18 females).

Facile Synthesis of a CuMoO Nanosheet Array for Electrochemical Reduction of Nitrite to Ammonia in Neutral Solution.

Electrochemical nitrite (NO) is a promising technology for NO removal and a sustainable method for generating valuable ammonia (NH), but this process is intricate and generates other byproducts. In this work, we propose a facile and low-cost method for the preparation of a CuMoO nanosheet array, which can serve as an efficient electrocatalyst for the reduction of NO to NH. The morphology of CuMoO can be adjusted by controlling the synthesis conditions.

FDG PET/CT in a Case of Metastasizing Pleomorphic Adenoma in the Ilium.

Although pleomorphic adenomas of the salivary glands are benign tumors, they can metastasize to distant organs without evidence of malignant transformation. We describe FDG PET/CT finding in a case of metastasizing pleomorphic adenoma in the right ilium occurring 22 years after initial surgical resection of a lip pleomorphic adenoma. On FDG PET/CT, the iliac metastasis appeared as an expansile osteolytic lesion with heterogeneous activity.

FDG PET/CT in a Case of Metastasizing Pleomorphic Adenoma in the Ilium.

Although pleomorphic adenomas of the salivary glands are benign tumors, they can metastasize to distant organs without evidence of malignant transformation. We describe FDG PET/CT finding in a case of metastasizing pleomorphic adenoma in the right ilium occurring 22 years after initial surgical resection of a lip pleomorphic adenoma. On FDG PET/CT, the iliac metastasis appeared as an expansile osteolytic lesion with heterogeneous activity.

Association between visceral adiposity index and prostate cancer in men aged 40 years and older: a nationwide cross-sectional study.

Objectives: This study aimed to elucidate the correlation of Visceral Adiposity Index (VAI) with prostate cancer (PCa) among men aged 40 years and older in the United States.

Methods: Analysis included multivariate linear and logistic regression, smoothing curve fitting, and threshold effect evaluation using 2003-2010 National Health and Nutrition Examination Survey (NHANES) data. The stability of this relationship across demographic groups was assessed via subgroup analyses and interaction tests.

Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor.

The inhibition of mutant KRAS proteins has emerged as a promising approach for treating KRAS-driven cancers, as evidenced by the clinical success of KRAS G12C inhibitors. KRAS G12D, the most common mutant, promises significant expansion of the addressable patient population; however, the reduced nucleophilicity of aspartate compared to cysteine poses significant challenges in balancing sufficient potency with ADME properties to support oral exposure. Herein, we describe the discovery of KRAS G12D inhibitor (), which achieves oral exposure in nonhuman primate (NHP).

Testing the Validity of the Montgomery-Koyama-Smith Equation for Calculating the Total Petal Area per Flower Using Two Rosaceae Species.

The size of floral organs is closely related to the successful reproduction of plants, and corolla size is, to some extent, indicative of the size of floral organs. Petals are considered to be homologous to leaves, so we also attempted to estimate the area of a single petal using the method that is typically employed for estimating single leaf area (i.e.

Trends in Heavy Metal Pollution in Agricultural Land Soils of Tropical Islands in China (2000-2024): A Case Study on Hainan Island.

Heavy metal contamination in agricultural soils has garnered increasing attention, yet research on the spatiotemporal trends of heavy metal pollution in tropical regions with multiple annual crop harvests remains limited. This study examines data from 41 studies published between 2000 and 2024, including 206 records from 4122 sampling points on Hainan Island in China, to investigate the spatial distribution and temporal trends of heavy metal pollution. The results reveal that the average concentrations of Cd, Pb, As, Cr, and Hg in surface soil samples from agricultural lands on Hainan Island are 0.

Alterations in the Microbiomes and Metabolic Profiles of the Ileal Between the Hu Sheep and East Friesian Sheep.

The East Friesian sheep is a dairy breed known for its high fertility and high milk production and is currently one of the best dairy sheep breeds in the world. This breed is known to have a poor disease-resistant phenotype compared to Hu sheep. Gut microbiota and metabolites play a role in host disease resistance.

Efficient photoresponsive one-dimensional covalent organic framework as oxidase-like enzyme for ultrasensitive detection of antioxidants.

Natural polyphenolic antioxidants are widely present in foods such as fruits and vegetables, meanwhile applied in food processing and storage to prevent the formation of harmful compounds. While excessive antioxidants lead to negative impacts on human health. Hence, it is crucial to accurately detect antioxidant levels in order to enhance the overall nutritional content and food safety.

Understanding structural-functional connectivity coupling in patients with major depressive disorder: A white matter perspective.

Purpose: To elucidate the structural-functional connectivity (SC-FC) coupling in white matter (WM) tracts in patients with major depressive disorder (MDD).

Methods: A total of 178 individuals diagnosed with MDD and 173 healthy controls (HCs) were recruited for this study. The Euclidean distance was calculated to assess SC-FC coupling.

The highly allo-autopolyploid modern sugarcane genome and very recent allopolyploidization in Saccharum.

Modern sugarcane, a highly allo-autopolyploid organism, has a very complex genome. In the present study, the karyotype and genome architecture of modern sugarcane were investigated, resulting in a genome assembly of 97 chromosomes (8.84 Gb).

Disentangling Sources of Momentum Fluctuations in Xe+Xe and Pb+Pb Collisions with the ATLAS Detector.

High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

Gut microbiota and blood biomarkers in IBD-Related arthritis: insights from mendelian randomization.

With the ongoing rise in the incidence of inflammatory bowel disease (IBD), its extraintestinal manifestations have garnered significant attention. IBD-related arthritis is notable for its insidious onset and unpredictability, presenting considerable challenges for clinical diagnosis and management. Factors such as gut microbiota, plasma proteins, inflammatory proteins, and biomarkers found in blood and urine may be closely associated with IBD-related arthritis.

Spatial heterogeneity of keyhole imagery coverage in China and imagery dataset cost estimation.

Keyhole imagery documented global surface from 1960 to 1980s and has contributed to earth surface change research, while evaluation of its' coverage spatial heterogeneity is rare. In this work the boundary vectors with attributes of all freely Keyhole images within China were obtained from USGS website to automatically investigate the spatial coverage characteristics using the ArcPy library in Python. Images were categorized into meter-level (C1), five-meter-level (C2), and ten-meter-level (C3).

Geometric series exists in nature: Evidence from sorted area sequences of floral parts and leaves.

The concept of a geometric series (GS) plays an important role in mathematics. However, it has been neglected in describing biological size series. Herein, we show that a GS describes the nonreproductive (perianth) parts of the flowers of four Magnoliaceae species and two Rosaceae species and the leaves of 60 Alangium chinense and 60 Shibataea chinensis shoots.