Interfacial coupling effects in two-dimensional ordered arrays for microwave attenuation.

With the development of nanotechnology, nano-functional units of different dimensions, morphologies, and sizes exhibit the potential for efficient microwave absorption (MA) performance. However, the multi-unit coupling enhancement mechanism triggered by the alignment and orientation of nano-functional units has been neglected, hindering the further development of microwave absorbing materials (MAMs). In this paper, two typical ZIF-derived nanomaterials are self-assembled into two-dimensional ordered polyhedral superstructures by the simple ice template method.

Replication kinetics, pathogenicity and virus-induced cellular responses of cattle-origin influenza A(H5N1) isolates from Texas, United States.

The host range of HPAIV H5N1 was recently expanded to include ruminants, particularly dairy cattle in the United States (US). Shortly after, human H5N1 infection was reported in a dairy worker in Texas following exposure to infected cattle. Herein, we rescued the cattle-origin influenza A/bovine/Texas/24-029328-02/2024(H5N1, rHPbTX) and A/Texas/37/2024(H5N1, rHPhTX) viruses, identified in dairy cattle and human, respectively, and their low pathogenic forms, rLPbTX and rLPhTX, with monobasic HA cleavage sites.

Stability of Lead(IV) Oxide in a Lead Pipe Scale and Its Potential Role in Corrosion Control.

Lead(IV) oxide (PbO) is an important component of the scale in many lead pipes used for water supply. Promoting conditions that maintain its stability could be an effective method for limiting lead release. In this study, we applied a method that combined electrochemical and free chlorine conditioning to form PbO scales on coupons.

Engineered extrachromosomal oncogene amplifications promote tumorigenesis.

Focal gene amplifications are among the most common cancer-associated mutations but have proven challenging to engineer in primary cells and model organisms. Here we describe a general strategy to engineer large (more than 1 Mbp) focal amplifications mediated by extrachromosomal DNAs (ecDNAs) in a spatiotemporally controlled manner in cells and in mice. By coupling ecDNA formation with expression of selectable markers, we track the dynamics of ecDNA-containing cells under physiological conditions and in the presence of specific selective pressures.

U-Shaped Relationship Between MSpO Levels and the Incidence of Frailty in Elderly OSA Patients: Findings from a Multicenter Cohort Study.

Background: Previous studies have demonstrated a significant correlation between obstructive sleep apnea (OSA) and frailty. However, the association of mean pulse oxygen saturation (MSpO) with frailty among OSA patients remains unconfirmed. This study aimed to explore this potential association using data from a multicenter, prospective cohort.

Interface Engineering of Thin-Film Lithium Phosphorus Oxynitride Electrolyte by Appropriate Oxygen Plasma Treatment for Flexible All-Solid-State Supercapacitor.

The interfacial incompatibility between lithium phosphorus oxynitride (LiPON) and anode greatly deteriorates the performance of thin-film all-solid-state supercapacitors (ASSSCs). This article investigates oxygen plasma treatment to improve the interface. Through appropriate plasma treatment, a LiO/LiPO composite layer is formed by replacing nitrogen with oxygen at the LiPON surface owing to strong reactivity of oxygen plasma.

A comparative study of GPT-4o and human ophthalmologists in glaucoma diagnosis.

Artificial intelligence (AI), particularly large language models like GPT-4o, holds promise for enhancing diagnostic accuracy in healthcare. This study evaluates the diagnostic performance of GPT-4o compared to human ophthalmologists in glaucoma cases. A prospective, observational study was conducted at a tertiary care ophthalmology center.

Industry-Level Electrocatalytic CO to CO Enabled by 2D Mesoporous Ni Single Atom Catalysts.

Electrocatalytic CO reduction reaction (eCORR) has captivated widespread attentions, yet achieving the requisite efficiency, selectivity and stability for industrial applications poses a persistent challenge. Here, we report the synthesis of 2D mesoporous Ni single atom catalysts in N-doped carbon framework via a bottom-up interfacial assembly strategy. The 2D mesoporous Ni-N-C catalyst showcases an ultrathin thickness (~6.

Endocannabinoid interference blocks post-global cerebral ischemia depression through prefrontal cortico-amygdala projections.

Up to 45% of patients surviving from transient global cerebral ischemia (GCI) after cardiac arrest develop post-global cerebral ischemia depression (PGCID), but how to treat PGCID is clinically unknown. Here we find that cannabinoid type-1 receptor (CBR) antagonists, CBR knockout and endocannabinoid (eCB) synthesis inhibition block acute stress-induced PGCID. Application of acute stress to GCI mice increases CBR activity from ventromedial prefrontal cortical (vmPFC) terminals synapsing with the basolateral amygdala (BLA) neurons, indicating the involvement of increased vmPFC-BLA synaptic eCB signaling in PGCID induction.

Potent neutralization by a RBD antibody with broad specificity for SARS-CoV-2 JN.1 and other variants.

SARS-CoV-2 continues to be a public health burden, driven in-part by its continued antigenic diversification and resulting emergence of new variants. By increasing herd immunity, current vaccines have improved infection outcomes for many. However, prophylactic and treatment interventions that are not compromised by viral evolution of the Spike protein are still needed.

Ductal pancreatic cancer interception by FGFR2 abrogation.

Unlabelled: Activating KRAS mutations are a key feature of pancreatic ductal adenocarcinoma (PDA) and drive tumor initiation and progression. However, mutant KRAS by itself is weakly oncogenic. The pathways that cooperate with mutant KRAS to induce tumorigenesis are less-defined.

Multi-drug resistant Pseudomonas aeruginosa isolation is an independent risk factor for recurrent hemoptysis after bronchial artery embolization in patients with idiopathic bronchiectasis: a retrospective cohort study.

Background: Currently, there is a lack of research on multi-drug resistant Pseudomonas aeruginosa (MDR-PA) isolation in bronchiectasis-related hemoptysis. The aim of this study to analyze the risk factors for recurrent hemoptysis following bronchial artery embolization (BAE) and compare the recurrent hemoptysis-free rates between MDR-PA, non-MDR-PA, and non-PA isolation.

Methods: A retrospective study was performed of patients diagnosed with idiopathic bronchiectasis-related recurrent hemoptysis who underwent BAE at an university-affiliated hospital.

Ag-Mediated Growth of Au/Ag-Cu Ternary Heterostructures for Selective Electrochemical CO Reduction.

Copper (Cu)-based nanocatalysts play crucial roles in the electrochemical CO reduction reaction (ECORR) for sustainable energy resources. Particularly, Cu-based nanostructures incorporating Au and Ag are promising, offering enhanced activity, selectivity, and stability. However, precise control over the structure and composition of heterostructures remains challenging, hindering the development of highly efficient catalysts.

Dual-Method Characterization and Optimization of Drilling Parameters for Picosecond Laser Drilling Quality in CFRP.

Carbon fiber-reinforced polymer (CFRP), known for its light weight, high strength, and corrosion-resistant properties, is extensively used in the lightweight design of satellite components, the optimization of electronic device casings, and the processing of high-performance composite materials in the defense sector. This study employs picosecond laser drilling technology for the precision machining of CFRP, demonstrating its advantages over traditional mechanical drilling and other unconventional methods in significantly reducing the heat-affected zone (HAZ) and enhancing hole wall quality. The optimization of laser power, scanning speed, and fill times via response surface methodology (RSM) significantly reduced the hole wall taper to 4.

Associations between visceral and liver fat and cardiac structure and function: a UK Biobank study.

Context: Different fat depots have connected to cardiovascular health.

Objective: We assessed the associations of abdominal magnetic resonance-quantified visceral adipose tissue (VAT) and liver fat (proton density fat fraction, PDFF) with cardiac magnetic resonance (CMR)-measured cardiac structure and function, and considered potential mechanism.

Methods: Our study encompassed 10,920 participants from the UK Biobank.

Analysis of Pollution Characteristics and Contributions of Firework Burnings in Nanchang during the Spring Festival.

This study investigates the impact of fireworks on air quality during the Spring Festival in Nanchang City, utilizing high-resolution monitoring data from February 7th to 15th, 2021. Significant variations in K concentrations were observed, indicating severe air quality impacts. During the most intense discharge event A, K concentrations were 20.

Smartphone addiction habit is positively associated with coronary artery disease and its severity in Chinese adults: a case-control study.

Background: Coronary artery disease (CAD) has a high incidence and poor prognosis worldwide. It has been confirmed that smartphone addiction (SA) habit can increase the incidence of hypertension and obesity in adolescents. However, the association of SA with CAD and its severity in Chinese adults remains largely unknown.

Effect of Ropivacaine Combined with Nalbuphine on Pain during Anaesthesia Recovery in Patients with Prostatic Hyperplasia Undergoing Transurethral Resection of Prostate.

Background: As a frequent disease, prostatic hyperplasia could be treated by transurethral resection of prostate (TURP). However, postoperative pain may affect the prognosis of patients to some extent, so exploring reasonable anaesthetic drugs is an important measure to reduce the recovery period of anaesthesia. This study used the combination of ropivacaine and nalbuphine for intraoperative anaesthesia in patients undergoing TURP to investigate its effect on pain during anaesthesia recovery.

β-1,4-Galactosyltransferase 1 protects against cerebral ischemia injury in mice by suppressing ferroptosis via the TAZ/Nrf2/HO-1 signaling pathway.

Background: Ischemic stroke leads a primary cause of mortality in human diseases, with a high disability rate worldwide. This study aims to investigate the function of β-1,4-galactosyltransferase 1 (B4galt1) in mouse brain ischemia/reperfusion (I/R) injury.

Methods: Recombinant human B4galt1 (rh-B4galt1) was intranasally administered to the mice model of middle cerebral artery occlusion (MCAO)/reperfusion.