Arginase inhibitory activities of chemical constituents from Beille leaves.

The methanolic extract of the leaves of Beille showed arginase inhibitory activity (40% at 100 µg/mL) and was then fractionated to obtain nine polyphenolic compounds. Their structures were elucidated on the basis of NMR spectroscopic data, and by comparison with data previously reported in the literature, as gallic acid (), 3,4-dihydroxybenzoic acid (), chlorogenic acid, (), corilagin (), cynaroside (), cosmosiin (), hyperoside () isoquercitrin ( and guajaverin (). These compounds have been evaluated as arginase inhibitors.