Publications by authors named "Yao C Hung"
Article Synopsis
- A phase III trial was conducted by the Asian Gynecologic Oncology Group to evaluate the effectiveness of maintenance chemotherapy in improving progression-free survival (PFS) for patients with stages III/IV ovarian cancer.
- The trial involved 45 newly-diagnosed patients who, after achieving complete remission, were randomly assigned to either receive maintenance chemotherapy (arm A) or be monitored (arm B), with results showing significant improvement in PFS for those on maintenance therapy.
- Although the maintenance therapy showed a better median PFS (55.5 months vs. 9.2 months), it did not significantly affect overall survival, and adverse events were more common in the treatment group, indicating a trade-off between benefits and side effects.
Nanotopography modulates cell characteristics and cell behavior. Nanotopological cues can be exploited to investigate the in-vivo modulation of cell characteristics by the cellular microenvironment. However, the studies explaining the modulation of tumor cell characteristics and identifying the transition step in cancer progressiveness are scarce.
View Article and Find Full Text PDFThis study was to evaluate the clinical impact of whole body positron emission tomography (PET) with 18F-fluoro-2-deoxyglucose (FDG) to detect recurrent cervical cancer based on asymptomatically elevated tumor marker levels. Whole-body FDG-PET was performed in 20 patients with suspected recurrent squamous cell carcinoma (SCC) of the cervix and asymptomatic tumor marker of SCC antigen increased serum levels but negative or equivocal other imaging modality results. All of these 20 asymptomatic patients have serum levels of SCC antigen > 1.
View Article and Find Full Text PDFObjective: In advanced cervical cancer, it has been reported that progression-free survival is significantly related to para-aortic lymph node metastasis. Computed tomography (CT) has been widely used for clinical staging, but its sensitivity for lymph nodal metastasis is low. Therefore, this prospective study was undertaken to evaluate (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) in detecting para-aortic lymph nodal metastasis in patients with locally advanced cervical carcinoma when CT findings were negative.
View Article and Find Full Text PDFMelanin was extracted from tea leaves (Thea sinensis Linn.) for the first time. Characterization of melanin proved similarity of the original compound to standard melanin.
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