Publications by authors named "Yanzuo Wu"
Article Synopsis
- - This meta-analysis examines the risk factors for thrombocytopenia (TP) in patients with systemic lupus erythematosus (SLE), a condition that can lead to severe complications and higher mortality rates.
- - The study reviewed 17 high-quality research articles, discovering that older age and clinical features like serositis, splenomegaly, and renal involvement increase the risk of TP, while conditions like arthritis and rash serve as protective factors.
- - The findings underscore the importance of early screening and intervention for SLE patients with identified risk factors to help mitigate the risk of TP and improve patient outcomes.
Background: Nonalcoholic fatty liver disease (NAFLD), also known as metabolic associated fatty liver disease (MAFLD), is a common liver condition characterized by excessive fat accumulation in the liver which is not caused by alcohol. The main causes of NAFLD are obesity and insulin resistance. Dachaihu decoction (DCHD), a classic formula in traditional Chinese medicine, has been proved to treat NAFLD by targeting different aspects of pathogenesis and is being progressively used in the treatment of NAFLD.
View Article and Find Full Text PDFBackground: Deposition of immune complexes drives podocyte injury acting in the initial phase of lupus nephritis (LN), a process mediated by B cell involvement. Accordingly, targeting B cell subsets represents a potential therapeutic approach for LN. Ginsenoside compound K (CK), a bioavailable component of ginseng, possesses nephritis benefits in lupus-prone mice; however, the underlying mechanisms involving B cell subpopulations remain elusive.
View Article and Find Full Text PDFIntroduction: Observational studies and clinical trials have supported the association between gut microbiota and psoriatic arthritis. However, the causal link between gut microbiota and psoriatic arthritis is still unclear.
Methods: A two-sample bi-directional Mendelian randomization analysis was performed using the summary statistics of gut microbiota from the largest available genome-wide association study meta-analysis (n = 13,266) conducted by the MiBioGen consortium.