Novel three-dimensional fibrous covalent organic frameworks constructed silver amalgam bridging for efficient organic dye adsorption and removal.

The construction of covalent organic frameworks (COFs) with unique structures has great significance in exploring the structure-function relationship and extending their potential applications. Fibrous COFs have demonstrated superior performance in specific application scenarios owing to the distinctive three-dimensional (3D) structure. Herein, we report a facile strategy for the fabrication of 3D COF nanofiber by exploiting silver amalgam as a bridging agent to assemble one-dimensional-extended PA-COF modules into a tubular structure.

Intercalating of AIEgens into MoS nanosheets to induce crystal phase transform for enhanced photothermal and photodynamic synergetic anti-tumor therapy.

A MoS-based nanotherapeutic platform was developed for synergetic photothermal and photodynamic anti-tumor therapy. AIEgens TFPy-SH molecules were intercalated into MoS nanosheets (MoS NSs) with S-deficiencies to give the nanocomposite MoS-TFPy. The AIEgens intercalation expanded the interlayer spacing of MoS NSs and induced the transform of MoS crystal phase from 2H to 1T, offering MoS-TFPy nanocomposite high molar absorption coefficient (5.

Photoreversible DNA nanoswitch-based eluent-free strategy for the direct and effective isolation of highly-active thrombin from whole blood.

This study proposes an eluent-free isolation strategy for the direct isolation of thrombin from whole blood via tandem temperature/pH dual-responsive polyether sulfone monolith and photoreversible DNA nanoswitch-functionalized metal-organic framework (MOF) aerogel. Temperature/pH dual-responsive microgel immobilized on polyether sulfone monolith was adopted to remove the matrix complexity of blood sample via size/charge screening effect. Photoreversible DNA nanoswitches, comprising thrombin aptamer, aptamer complementary ssDNA (cDNA) and the azobenzene-modified ssDNA (control DNA), were functionalized on MOF aerogel to offer efficient capturing of thrombin under irradiation of ultraviolet light (365 nm), driven by electrostatic and hydrogen bond interactions.

Rational synthesis of carbon dots with phosphate ester group for direct mapping of endogenous alkaline phosphatase and polarity monitoring in living cells.

Carbon dots (CDs) have been extensively employed in biomolecule imaging. However, the imaging of biological enzymes with CDs has not been reported, which greatly limits their application in biological imaging. Herein, for the first time, a new type of fluorescent CDs is elaborately designed to realize the direct mapping of alkaline phosphatase (ALP) in cells.

Fabrication of P and N Co-Doped Carbon Dots for Fe Detection in Serum and Lysosomal Tracking in Living Cells.

Doping with heteroatoms allows the retention of the general characteristics of carbon dots while allowing their physicochemical and photochemical properties to be effectively modulated. In this work, we report the preparation of ultrastable P and N co-doped carbon dots (PNCDs) that can be used for the highly selective detection of Fe and the tracking of lysosomes in living cells. Fluorescent PNCDs were facilely prepared via a hydrothermal treatment of ethylenediamine and phytic acid, and they exhibited a high quantum yield of 22.

One-step hydrothermal synthesis of WS quantum dots as fluorescent sensor for sensitive and selective recognition of hemoglobin and cardiac biomarker myoglobin.

Transition metal dichalcogenide (TMD) dots exhibit excellent photoluminescence performance due to the quantum confinement effect and edge effect, and are extensively applied in electronic and optical devices, sensors, catalysis, and bioimaging. In this work, WS quantum dots (WS QDs) were prepared under a simple one-step hydrothermal method by optimizing the reaction conditions, and a quantum yield of 11.23% was achieved.