Publications by authors named "Yanzhe Jia"

Article Synopsis
  • The study examines how m6A methylation in wheat is affected by drought stress, finding that TaETC9 may help regulate drought tolerance through RNA methylation.
  • Researchers identified 4221 m6A peaks in 3733 genes, with 373 peaks showing different expressions under drought conditions compared to control conditions.
  • The results indicate that higher levels of m6A are linked to increased mRNA abundance, and the deletion of TaETC9 increased drought sensitivity, suggesting its essential role in drought resistance in wheat.
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Phytochemical investigation on the roots of Kadsura coccinea led to the isolation five previously unknown dibenzocyclooctadiene lignans, named heilaohusuins A-E (1-5). Their structures determined by NMR spectroscopy, HR-ESI-MS, and ECD spectra. Hepatoprotection effects of a series of dibenzocyclooctadiene derivatives (1-68) were investigated against acetaminophen (APAP) induced HepG2 cells.

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belongs to the Schisandroideae subfamily of Magnoliaceae. Plants from genus are widely distributed in the South and Southwest of China. The plants of the genus are widely used as folk medicine for a long time in history, with the functions of relieving pain, promoting '' circulation, activating blood resolve stasis, and applications in the treatment of rheumatoid arthritis and gastroenteric disorders.

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Article Synopsis
  • Researchers isolated fourteen new 2,2'-cyclolignans (heilaohuguosus A-N), four new aryltetrahydronaphthalene lignans (heilaohuguosus O-R), and one tetrahydrofuran lignan (heilaohuguosu S) from Kadsura coccinea fruits, along with twenty-seven known lignan analogues.
  • The structures of the new compounds were determined using advanced spectroscopic techniques, including 1D and 2D-NMR and CD experiments.
  • Some of the isolated compounds, particularly heilaohuguosus A and L, demonstrated significant hepatoprotective effects against acetaminophen (APAP)-induced toxicity in liver cells,
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belongs to medicinally important genus from the Schisandraceae family. It has been used in traditional Chinese medicine (TCM) for the treatment of rheumatoid arthritis and gastroenteric disorders. The initial phytochemical work focused on the identification of some structurally novel and diverse natural products, which turned the attention of many researchers towards this plant.

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Twenty-four compounds were isolated from the roots of Hua, including a new octopamine dimer, named -bis(-feruloyl)octopamine . The structure was established on the basis of spectroscopic and chemical methods. All the extracts and compounds were evaluated for cytotoxic and antioxidant activities by using MTT and chemiluminescence assay.

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