Melatonin enhances metal oxide nanoparticles tolerance in rice seedlings through dual regulation of antioxidant defense and photosynthetic efficiency.

The growing utilization of metal oxide nanoparticles (MONPs) presents novel and potential hazards to plants. However, the impacts of MONPs on plants and the mechanisms underlying their tolerance to MONPs remain unclear. In this study, we demonstrated that both CuO and ZnO nanoparticles hindered plant growth and triggered oxidative damage in rice seedlings.

A de novo evolved gene contributes to rice grain shape difference between indica and japonica.

The role of de novo evolved genes from non-coding sequences in regulating morphological differentiation between species/subspecies remains largely unknown. Here, we show that a rice de novo gene GSE9 contributes to grain shape difference between indica/xian and japonica/geng varieties. GSE9 evolves from a previous non-coding region of wild rice Oryza rufipogon through the acquisition of start codon.

Isoschaftoside Reverses Nonalcoholic Fatty Liver Disease via Activating Autophagy and .

Nonalcoholic fatty liver disease (NAFLD) is the most common metabolic liver disease globally, and the incidence of NAFLD has been increasing rapidly year by year. Currently, there is no effective pharmacotherapy for NAFLD. Therefore, studies are urgently needed to explore therapeutic drugs for NAFLD.

Inhibition of NEK7 Suppressed Hepatocellular Carcinoma Progression by Mediating Cancer Cell Pyroptosis.

NIMA-related kinase 7 (NEK7) is a serine/threonine kinase involved in cell cycle progression mitotic spindle formation and cytokinesis. It has been related to multiple cancers, including breast cancer, hepatocellular cancer, lung cancer, and colorectal cancer. Moreover, NEK7 regulated the NLRP3 inflammasome to activate Caspase-1, resulting in cell pyroptosis.

Nucleotide Diversity of the Maize Gene and Association With Ear Traits.

The maize ( L) gene, encoding a protein of () family, has been demonstrated to be involved in cell division, expansion, and differentiation. In the present study, the genomic sequences of the locus were re-sequenced in 224 inbred lines, 56 landraces and 30 teosintes, and the nucleotide polymorphism and selection signature were estimated. A total of 501 variants, including 415 SNPs and 86 Indels, were detected.

NEK7 Promotes Pancreatic Cancer Progression And Its Expression Is Correlated With Poor Prognosis.

The prognosis for pancreatic ductal adenocarcinoma (PDAC) patients is still dismal. Elucidation of associated genomic alteration may provide effective therapeutic strategies for PDAC treatment. NIMA-related protein kinase 7 is widely expressed in various tumors, including breast cancer, colorectal cancer and lung cancer, and promotes the proliferation of liver cancer cells and .