Publications by authors named "Yanying Yue"
Microb Cell Fact
November 2024
Article Synopsis
- 2-O-α-D-glucosyl glycerol (2-αGG) is a highly sought-after ingredient in cosmetics, healthcare, and food, but its production using sucrose phosphorylase (SPase) has limitations due to unknown glucosyl-acceptor affinity and thermodynamic features.
- Researchers isolated and tested three SPases from different bacteria, finding that one from Lactobacillus reuteri (LrSP) was the most effective for producing 2-αGG but had a low conversion rate.
- By enhancing and modifying another strain, Lb. paracasei, the study achieved a significant increase in production efficiency, ultimately yielding 203.21 g/L of 2-α
Int J Food Microbiol
January 2025
Article Synopsis
- Lactococcus lactis is vital for dairy production, and the study identifies key genes (ffh and ftsY) in this bacterium's membrane protein targeting system, the SRP pathway, which hadn't been thoroughly explored before.
- Mutations in the ffh or ftsY genes didn't kill the bacteria but resulted in longer lag phases, lower biomass production, and reduced growth efficiency under aerobic respiration, affecting their ability to metabolize glucose and produce lactate.
- The study found that the SRP pathway components are essential for acid resistance, as mutations led to a significant drop in cell survival under acidic conditions, and disrupted protein synthesis and metabolism processes in Lactococcus lactis.
