Helical Crystals in Aliphatic Copolyesters: From Chiral Amplification to Mechanical Property Enhancement.

We demonstrate herein a bottom-up strategy for achieving helical crystals via chiral amplification in copolyesters by incorporating a small amount of (d)-isosorbide into semicrystalline polyester, poly(ethylene brassylate) (PEB). During bulk crystallization of poly(ethylene--isosorbide brassylate)s, the molecular chirality of isosorbide in the amorphous region is transferred to PEB crystal chirality and amplified by the formation of right-handed helical crystals. Increasing isosorbide content or reducing crystallization temperature leads to thinner PEB lamellae crystals, strengthening chiral amplification by forming superhelices with a smaller helical pitch.

Resveratrol inhibited hepatocyte apoptosis and alleviated liver fibrosis through miR-190a-5p /HGF axis.

Background: Hepatocyte apoptosis plays an important role in the progression of liver fibrosis. Overexpression of HGF (Hepatocyte growth factor) can reduce hepatocyte apoptosis and alleviate liver fibrosis. Our study aims to investigate whether resveratrol (Res) can alleviate liver fibrosis through miR-190a-5p /HGF axis.

Contributions of gains and losses to attentional capture and disengagement: evidence from the gap paradigm.

It is known that movements of visual attention are influenced by features in a scene, such as colors, that are associated with value or with loss. The present study examined the detailed nature of these attentional effects by employing the gap paradigm-a technique that has been used to separately reveal changes in attentional capture and shifting, and changes in attentional disengagement. In four experiments, participants either looked toward or away from stimuli with colors that had been associated either with gains or with losses.