Lanthanide-Porphyrin MOF as a Multifunctional Platform for Detection and Integrated Elimination of Cr(VI) and Ciprofloxacin.

Environmental concerns are driving the development of eco-friendly and effective methods for contaminant monitoring and remediation. In this study, a lanthanide porphyrin-based MOF with dual fluorescence sensing and photocatalytic properties was synthesized and applied for the detection and combined removal of Cr(VI) and ciprofloxacin (CIP). Using different excitation wavelengths, the material exhibited selective detection of Cr(VI) via fluorescence quenching and CIP through fluorescence enhancement.

An Intelligent Electrochemical Multi-Enzyme Molecular Machine for Chiral Chemical.

In vitro multi-enzyme synthesis pathways harness the core elements of cellular synthesis while simplifying the complexities of cellular processes, facilitating the production of high-value chemicals. However, these in vitro synthesis processes often operate like a "black box," with limited monitoring of each reaction step, leading to a low substrate conversion efficiency. In this study, we present an intelligent multi-enzyme molecular machine(iMEMM) as a model system for achieving the deracemization of D, L-phosphinothricin (D, L-PPT).

Water-Stable Ln-MOF as a multi-emitting luminescent sensor for the detection of metal ions and pharmaceuticals.

The development of innovative multi-emission sensors for the rapid and accurate detection of contaminants is both vital and challenging. In this study, utilizing two rigid ligands (HICA and HBTEC), a series of water-stable bimetallic organic frameworks (EuTb-MOFs) were synthesized. Luminescent investigations have revealed that EuTb-MOF-1 exhibits prominent multiple emission peaks, attributed to the distinctive fluorescence characteristics of Eu(III) and Tb(III) ions.

Separable Metal-Organic Framework-Based Materials for the Adsorption of Emerging Contaminants.

Thousands of chemicals have been released into the environment in recent decades. The presence of emerging contaminants (ECs) in water has emerged as a pressing concern. Adsorption is a viable solution for the removal of ECs.

Imparting Multifunctionality in Zr-MOFs Using the One-Pot Mixed-Linker Strategy: The Effect of Linker Environment and Enhanced Pollutant Removal.

The development of mixed-linker metal-organic frameworks (MOFs) is an efficient strategy to improve the performance of MOFs. Herein, we successfully integrate tetrakis(4-carboxyphenyl)porphyrin (TCPP) into different Zr-MOFs via a facile one-pot solvothermal synthesis while preserving the integrity of their frameworks. The functional groups, length of primary linkers, and the inner pore structure significantly affected the properties of the synthesized TCPP@MOFs, such as surface area, average pore size, and O productivity.

Pollution characteristics and health risk assessment of PM-bound arsenic: a 7-year observation in the urban area of Jinan, China.

The aim of the study was to analyze the temporal trends, pollution sources, and carcinogenic health risks associated with PM-bound arsenic (As). A total of 588 PM samples were collected in Jinan during January 2014-December 2020. The content and distribution characteristics were determined for As and Al in PM, and the pollution sources were identified based on enrichment factors (EFs).

Removal of aqueous pharmaceuticals by magnetically functionalized Zr-MOFs: Adsorption Kinetics, Isotherms, and regeneration.

The functionalization of metal-organic frameworks (MOFs) is imperative and challenging for the development of practical MOF-based materials. Herein, a magnetically functionalized Zr-MOF (FeO@MOF-525) was synthesized via secondary-growth approach to obtain an easily-separated and recyclable adsorbent for the removal of pharmaceuticals (tetracycline (TC) and diclofenac sodium (DF)). After loading FeO nanoparticles (NPs), due to the increase of micropore volume and specific surface area caused by defects, the adsorption performance of FeO@MOF-525 was improved.

Reduced mitochondrial DNA copy number in occupational workers from brominated flame retardants manufacturing plants.

Decabrominated diphenyl ether (BDE-209) and its substitute decabromodiphenyl ethane (DBDPE) are two flame retardants that have similar structure and are widely used in various industrial products. The accumulation and potential toxicity of them to human health have already aroused attention, and some research showed that they may affect mitochondrial function. Therefore, this study focused on the population with high exposure to brominated flame retardants (BFRs) and the related changes in mtDNA copy number (mtDNAcn) in whole blood.

Rational construction of Ni(OH) nanoparticles on covalent triazine-based framework for artificial CO reduction.

Artificial photoreduction of CO to chemical fuel is an intriguing and reliable strategy to tackle the issues of energy crisis and climate change simultaneously. In the present study, we rationally constructed a Ni(OH)-modified covalent triazine-based framework (CTF-1) composites to serve as cocatalyst ensemble for superior photoreduction of CO. In particular, the optimal Ni(OH)-CTF-1 composites (loading ratio at 0.

Tetracycline removal from aqueous solution using zirconium-based metal-organic frameworks (Zr-MOFs) with different pore size and topology: Adsorption isotherm, kinetic and mechanism studies.

The adsorptive removal of tetracycline (TC) was studied with three types of zirconium-based metal-organic frameworks (Zr-MOFs), UiO-66, NU-1000 and MOF-525. The adsorption kinetics best fitted with the pseudo-second-order kinetic model and the adsorption equilibrium was rapidly reached within 40 min on UiO-66 and NU-1000, and 120 min on MOF-525. The adsorption isotherms best fitted with Sips model, and the maximum Sips adsorption capacities of TC on UiO-66, NU-1000 and MOF-525 were 145 mg·g, 356 mg·g and 807 mg·g respectively, which were much higher than common adsorbents.

Genomic prediction across years in a maize doubled haploid breeding program to accelerate early-stage testcross testing.

Genomic selection with a multiple-year training population dataset could accelerate early-stage testcross testing by skipping the first-stage yield testing, which significantly saves the time and cost of early-stage testcross testing. With the development of doubled haploid (DH) technology, the main task for a maize breeder is to estimate the breeding values of thousands of DH lines annually. In early-stage testcross testing, genomic selection (GS) offers the opportunity of replacing expensive multiple-environment phenotyping and phenotypic selection with lower-cost genotyping and genomic estimated breeding value (GEBV)-based selection.

In Situ Synthesis of Defect-Engineered MOFs as a Photoregenerable Catalytic Adsorbent: Understanding the Effect of LML, Adsorption Behavior, and Photoreaction Process.

Defect-engineering is an exciting strategy for the modification of metal-organic frameworks (MOFs), which can go beyond the limit of conventional MOFs, tailor material properties, and incorporate multiple functionalities. Herein, based on the large mixed-linker approach, we successfully integrated tetrakis(4-carboxyphenyl)porphyrin (TCPP) into stable UiO-66 via an in situ one-pot synthetic method and used the obtained material for the removal of diclofenac (DF). TCPP@UiO-66 maintained the structure, excellent stability, and porosity of UiO-66.

Pollution characteristics and chronic health risk assessment of metals and metalloids in ambient PM in Licheng District, Jinan, China.

PM samples were collected at the Wangsheren primary school site in Licheng District of Jinan, China, during 2016. Eleven metals and metalloids including Al, As, Be, Cd, Cr, Hg, Mn, Ni, Pb, Sb and Se in PM were measured by inductively coupled plasma-mass spectroscopy. The annual average mass concentration of PM was found to be 88.

Multicenter surveillance study of surgical site infection and its risk factors in radical resection of colon or rectal carcinoma.

Background: Colorectal surgery is associated with high rates of surgical site infection (SSI). We investigated SSI in radical resection of colon or rectal carcinoma and its epidemiological distribution in 26 hospitals in China.

Methods: We conducted prospective surveillance of patients who underwent radical resection of colon or rectal carcinoma in 26 selected hospitals from January 2015 to June 2016.

BrAPI-an application programming interface for plant breeding applications.

Motivation: Modern genomic breeding methods rely heavily on very large amounts of phenotyping and genotyping data, presenting new challenges in effective data management and integration. Recently, the size and complexity of datasets have increased significantly, with the result that data are often stored on multiple systems. As analyses of interest increasingly require aggregation of datasets from diverse sources, data exchange between disparate systems becomes a challenge.

Understanding the adsorption of sulfonamide antibiotics on MIL-53s: Metal dependence of breathing effect and adsorptive performance in aqueous solution.

This investigation is based on experimental data to deeply understand the unusual adsorption behavior of the flexible MIL-53s in aqueous solution. In contrast to the strongly flexible MIL-53(Cr) and MIL-53(Al) with large pore form (lp) in water and in their anhydrous state, MIL-53(Fe) exhibits narrow pore form (np) or very narrow pore form (vnp), indicating that breathing effect depends on the nature of the metal. Sulfamethoxazole (SMZ) adsorption results demonstrated that the maximum adsorption capacities predicted by Langmuir model were 1.

Twist Expression in Circulating Hepatocellular Carcinoma Cells Predicts Metastasis and Prognoses.

Hepatocellular carcinoma (HCC) is one of the leading malignancies worldwide. Enumeration of circulating tumor cells (CTCs) has been demonstrated to be a prognostic indicator in HCC. Twist plays a critical role in metastasis and has been proposed as a biomarker for epithelial-mesenchymal transition (EMT).

A comparative study of rigid and flexible MOFs for the adsorption of pharmaceuticals: Kinetics, isotherms and mechanisms.

Recently metal-organic frameworks (MOFs) have attracted great attention in the field of environmental remediation. In this article, rigid MIL-101(Cr) and flexible MIL-53(Cr) were synthesized and used for the adsorption of two typical pharmaceuticals, clofibric acid (CA) and carbamazepine (CBZ), from water. The adsorption equilibrium was rapidly reached within 60 min and the kinetics best fitted with the pseudo-second-order kinetic model.

TGF- Overexpression in Breast Cancer Bone Metastasis and Primary Lesions and TGF- Enhancement of Expression of Procancer Metastasis Cytokines in Bone Marrow Mesenchymal Stem Cells.

Bone metastasis (BM) is the advanced complication of breast cancer, while bone marrow-derived mesenchymal stem cells (BMSCs) in the microenvironment unclearly contribute to cancer metastasis. This study investigated potential roles of transforming growth factor- (TGF-) in the interaction between breast cancer and BMSCs in BM. Clinical cases of breast cancer with bone metastasis (BMBC), breast cancer without bone metastasis (Non-BM-BC), and benign fibroadenoma (Benign) were enlisted in a retrospective study.

Adsorptive removal of emerging polyfluoroalky substances F-53B and PFOS by anion-exchange resin: A comparative study.

Chrome plating is an important emission source of perfluorinated compounds (PFCs) industrial uses in China, where two commercial products potassium 2-(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyloxy) (F-53B) and perfluorooctane sulfonate (PFOS) are applied as mist suppressant, causing non-negligible environmental risk. In this paper, anion-exchange resin IRA67 was evaluated for F-53B and PFOS removal from simulated and actual wastewater. Adsorption kinetics exhibited higher adsorption velocity and capacity of IRA67 for PFOS than F-53B due to their difference in molecular structures.

Photoreactivity of Metal-Organic Frameworks in Aqueous Solutions: Metal Dependence of Reactive Oxygen Species Production.

Promising applications of metal-organic frameworks (MOFs) in various fields have raised concern over their environmental fate and safety upon inevitable discharge into aqueous environments. Currently, no information regarding the transformation processes of MOFs is available. Due to the presence of repetitive π-bond structure and semiconductive property, photochemical transformations are an important fate process that affects the performance of MOFs in practical applications.

Combining powers of linkage and association mapping for precise dissection of QTL controlling resistance to gray leaf spot disease in maize (Zea mays L.).

Background: Gray Leaf Spot (GLS causal agents Cercospora zeae-maydis and Cercospora zeina) is one of the most important foliar diseases of maize in all areas where the crop is being cultivated. Although in the USA the situation with GLS severity is not as critical as in sub-Saharan Africa or Brazil, the evidence of climate change, increasing corn monoculture as well as the narrow genetic base of North American resistant germplasm can turn the disease into a serious threat to US corn production. The development of GLS resistant cultivars is one way to control the disease.