Publications by authors named "Yanshou Zhang"
Article Synopsis
- The study aimed to create a prediction tool for breast cancer survival rates in elderly women using existing data from patient records.
- Researchers collected clinical data from 889 elderly breast cancer patients and used statistical models to identify important factors for predicting 3- and 5-year overall survival (OS) and disease-free survival (DFS).
- The developed nomograms showed strong accuracy in predicting patient outcomes, indicating their potential for personalized treatment plans and better risk assessment in clinical settings.
Article Synopsis
- Totally implantable venous access devices (TIVADs) are commonly used in cancer patients, but thrombotic occlusion is a frequent issue when treatment is on pause.
- A study analyzing clinical data from 1586 breast cancer patients with TIVADs found a 6.1% incidence rate of thrombotic occlusion confirmed by angiography.
- Key risk factors influencing thrombotic occlusion included the catheter's insertion site, size, and how long it was left in, with optimal conditions being the right internal jugular vein, smaller catheter size, and shorter indwelling times.
Introduction: The objective of our study was to explore the expression pattern of circular ribonucleic acid (RNA)_0,007,331 (circ_0,007,331) in breast cancer (BC) and its functional association with cellular paclitaxel (PTX) resistance and proliferation, migration, invasion and apoptosis.
Methods: Real-time quantitative polymerase chain reaction was applied to measure RNA expression. The PTX resistance of BC cells was analyzed by cell counting kit-8 assay.
Aim: Exosomes has been shown to be involved in the regulation of cancer progression. However, the role of exosome miR-134-5p in breast cancer (BC) progression is unclear.
Methods: Exosomes were extracted from BC cells (MCF-7 and MDA-MB-231) using differential centrifugation and were observed by transmission electron microscope (TEM).
Introduction: As an under-reported, severe, and life-threatening complication, catheter-related right atrial thrombosis (CRAT) can appear at any age with any type of central venous catheter (CVC). However, most reports are limited to hemodialysis patients with CVC. Totally implantable venous access port (TIVAP) is widely used for the infusion of high-concentration chemotherapeutic drugs in cancer patients.
View Article and Find Full Text PDFBackground: High expression of leucine-rich alpha-2-glycoprotein 1 (LRG1) is closely related to angiogenesis, which may play an important role in promoting invasion and metastasis. However, the current literature has yet to clarify the clinical significance of LRG1 in breast cancer.
Objectives: The purpose of this work was to validate the correlation between LRG1 expression and prognosis in early breast cancer.
Purpose: Adverse events (AEs) assessment by clinicians is a standard practice in a clinical setting. However, studies have found clinicians tend to report fewer AEs, especially subjective AEs. We aimed to explore the difference of subjective AEs assessment between clinicians and patients based on PRO-CTCAE, and to discuss the necessity of incorporating patient into the evaluation of AEs.
View Article and Find Full Text PDFThe endocrine therapy for breast cancer could be traced back to the excision of the metastatic breast cancer by oophorectomy in a premenopausal women performed by Beatson in 1896. After the development of more than 100 years, endocrine therapy plays an important role in adjuvant therapy, the rescuing treatment of its recurrence due to metastasis, and the new adjuvant endocrine therapy for breast cancer. Through analyzing the changes in the 4 aspects of endocrine treatment of breast cancer, i.
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