Calcium-Salt-Enhanced Fiber Membrane with High Infrared Emission and Hydrophilicity for Efficient Passive Cooling.

Radiative cooling fabrics have gained significant attention for their ability to enhance comfort without consuming extra energy. Nevertheless, sweat accumulation on the skin and diminishing cooling efficiency usually exist in the reported polymer cooling membranes. Herein, we report a universal method to obtain a calcium (Ca)-salt-enhanced fiber membrane with high infrared emission and hydrophilicity for efficient passive cooling and flame retardancy.

Dual-Mode Integrated Janus Films with Highly Efficient NaH PO -Enhanced Infrared Radiative Cooling and Solar Heating for Year-Round Thermal Management.

The currently available materials cannot meet the requirements of human thermal comfort against the hot and cold seasonal temperature fluctuations. In this study, a dual-mode Janus film with a bonded interface to gain dual-mode functions of both highly efficient radiative cooling and solar heating for year-round thermal management is designed and prepared. The cooling side is achieved by embedding NaH PO particles with high infrared radiation (IR) emittance into a porous polymethyl methacrylate (PMMA) film during pore formation process, which is reported for the first time to the knowledge.

Glucose- and pH-Responsive Supramolecular Polymer Vesicles Based on Host-Guest Interaction for Transcutaneous Delivery of Insulin.

Smart insulin delivery platforms having the ability of mimicking pancreatic cells are highly expected for diabetes treatment. Herein, a smart glucose-sensitive insulin delivery platform on the basis of transcutaneous microneedles has been designed. The as-prepared microneedles are composed of glucose- and pH-responsive supramolecular polymer vesicles (PVs) as the drug storage and water soluble polymers as the matrix.

Block copolymer@ZIF-8 nanocomposites as a pH-responsive multi-steps release system for controlled drug delivery.

Developing the hybrid nanosystems for controlled drug release is still a challenging task. In this work, pH-responsive core-shell nanocomposites have been prepared by the growth of zeolitic imidazolate framework-8 (ZIF-8) on the surface of polymeric aggregates self-assembled from poly(ε-caprolactone)--poly ( vinylbenzyl chloride/bipyridine) (PCL--(PVBC/BPy), BCP for short) in water. The core of the micelles or the inner cavity of vesicles serves as the drug storage reservoir for the doxorubicin hydrochloride (DOX) and the ZIF-8 shells act as the gatekeepers to prevent drug premature release at physiological environment.

Reactive Oxygen Species Synergistic pH/HO-Responsive Poly(l-lactic acid)--poly(sodium 4-styrenesulfonate)/Citrate-Fe(III)@ZIF-8 Hybrid Nanocomposites for Controlled Drug Release.

Combination of photodynamic therapy and chemotherapeutic drugs is a promising strategy to achieve enhanced anticancer effect. In this study, a novel reactive oxygen species (ROS) synergistic pH/HO-responsive nanocomposite has been prepared from the self-assembly of poly(l-lactic acid)--poly(sodium 4-styrenesulfonate) in aqueous solution, followed by addition of ferric citrate (Cit-Fe(III)) through electrostatic interaction and growing ZIF-8 among the surface of the particles. Upon HO and visible light stimuli, efficient ROS such as hydroxyl radicals (OH) and sulfate radicals (SO) can be generated through the catalyst of Cit-Fe(III).

Redox and pH responsive polymeric vesicles constructed from a water-soluble pillar[5]arene and a paraquat-containing block copolymer for rate-tunable controlled release.

Herein, for rate-tunable controlled release, pH and redox dual responsive polymeric vesicles were constructed based on host-guest interaction between a water soluble pillar[5]arene (WP5) and a paraquat-containing block copolymer (BCP) in water. The yielding polymeric vesicles can be further applied in the controlled release of a hydrophilic model drug, doxorubicin hydrochloride (DOX). The drug release rate is regulated depending on the type of single stimulus or the combination of two stimuli.