Publications by authors named "Yanrui Cui"

Genetic interactions (GIs) refer to two altered genes having a combined effect that is not seen individually. They play a crucial role in influencing drug efficacy. We utilized CGIdb 2.

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Alternative splicing (AS) participates in tumor development and tumor microenvironment formation. However, the landscape of immune-infiltrating AS events in pan-cancer and mechanisms of AS in lung adenocarcinoma (LUAD) have not been comprehensively characterized. We systematically profiled the immune-infiltrating AS event landscape of pan-cancer using data from The Cancer Genome Atlas, analyzing both commonalities and specific characteristics among different cancer types.

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Starvation and antibiotics pollution are two frequent perturbations during breeding wastewater treatment process. Supplying magnetite into anaerobic system has been proved efficient to accelerate microbial aggregates and alleviate the adverse effect caused by process disturbance. Nevertheless, whether these magnetite-based granules are still superior over normal granules after a long-term starvation period remains unknown, the responsiveness of these granules to antibiotics stress is also ambiguous.

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In this study, the effect of magnetite amendment on anaerobic digestion was investigated at three increasing salinity levels (0.5%, 1% and 2% NaCl). The amendment of magnetite enhanced the methane yield by 36.

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Ciprofloxacin (CIP) removal efficiency in aqueous solutions in the ultrasonic (US), KSO, and US/KSO systems was investigated. The free radical generation and action ratio were studied based on variations of KSO concentration, ultrasonic power, pH, and the addition of isopropanol (ISP) or tert-butyl alcohol (TBA) in the US/KSO system. The results showed that under conditions of 20 mg·L CIP concentration, 20 mmol·L KSO concentration, an ultrasonic power of 360 W and pH = 7, CIP removal efficiency in the US/KSO system was 92.

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In current study, the enhancement effect of magnetite on anaerobic digestion was evaluated at increased organic loading rate (OLR) from 1.6 to 25.6 kg COD·m·d.

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Short- and medium-chain chlorinated paraffins (SCCPs and MCCPs) were measured in sediment and suspended particulate matter (SPM) from the middle and lower reaches of the Yellow River in the three seasons to elucidate their environmental behavior. The mean concentrations of ∑SCCPs and ∑MCCPs were 262 and 97.1 ng g dw (dry weight) in sediment and 17,055 and 2573 ng g dw in SPM, respectively, and higher SCCP levels did not clearly reflect a shift to more MCCPs in this section of the Yellow River.

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Influence of biological activated carbon (BAC) on simultaneous nitrification and denitrification (SND) in inflow with different C/N ratios was investigated with continuous operation of BAC reactor and SBR. Methanol was added as carbon source and the inflow C/N ratio was set to 3, 5, 8 and 10 to run for about 120 cycles, under conditions of indoor temperature (15-27℃), initial DO 2-3mg·L. The TN removal efficiency and stability of two reactors were compared.

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A new anthraquinone derivative (AORha) was synthesized. Its interactions with human serum albumin (HSA) and calf thymus DNA (ctDNA) were investigated by fluorescence spectroscopy, UV-visible absorption spectroscopy and molecular modeling. Cell viability assay and cell imaging experiment were performed using cervical cancer cells (HepG2 cells).

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The water quality improvement of landfill leachate after sequencing batch reactor (SBR) activated sludge process were evaluated by chemical oxygen demand (COD), dissolved organic matter (DOM) fractions, and three-dimensional excitation-emission matrix (EEM), from which the new understanding was obtained. The results indicated that less than 14% COD was removed by SBR. The EEM of leachate and SBR effluent showed that HPO-A and TPI-A were appeared in the peak C, while the HPI, HPO-N, and TPI-N could not be found due to dilution.

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N, N-bis (carboxymethyl) glutamic acid tetrasodium (GLDA), a novel biodegradable and green chelating agent, has excellent metal chelating ability. Batch experiment was conducted to study the extraction process of Cd, Ni, Cu and Zn in industrial sludge using GLDA. The effects of contact time, pH of the system, content of chelating agent were investigated, and the forms of heavy metals in sludge pre- and post-extraction using the modified BCR sequential extraction procedure were studied.

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Tetrasodium of N,N-bis(carboxymethyl) glutamic acid (GLDA), a novel readily biodegradable chelating ligand, was employed for the first time to remove heavy metals from industrial sludge generated from a local battery company. The extraction of cadmium, nickel, copper, and zinc from battery sludge with the presence of GLDA was studied under different experimental conditions such as contact times, pH values, as well as GLDA concentrations. Species distribution of metals in the sludge sample before and after extraction with GLDA was also analyzed.

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Article Synopsis
  • The study examined how different doses of biological activated carbon (BAC) affect the removal of chemical oxygen demand (COD) in landfill leachate treatment, finding that higher BAC dosages lead to better removal efficiencies.
  • The COD removal rates increased with BAC dosages of 0 g (12.9%), 100 g (19.6%), and 300 g (27.7%), indicating a positive correlation between BAC dosage and removal efficiency.
  • Additionally, the production of carbon dioxide during aeration increased with higher BAC doses, suggesting that the combination of adsorption and bioregeneration by BAC enhances the breakdown of stubborn organic materials in leachate.
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High level of heavy metals in industrial sludge was the obstacle of sludge disposal and resource recycling. In this study, iminodisuccinic acid (IDS), a biodegradable chelating ligand, was used to remove heavy metals from industrial sludge generated from battery industry. The extraction of cadmium, copper, nickel, and zinc from battery sludge with aqueous solution of IDS was studied under various conditions.

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The interaction of one anthraquinone derivative (AOMan) with calf thymus deoxyribonucleic acid (ctDNA) was systematically investigated at physiological pH 7.4 by fluorescence spectroscopy and molecular modeling. Binding constants of ctDNA with AOMan were calculated at different temperatures.

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Development of highly efficient anode is critical for enhancing the power output of microbial fuel cells (MFCs). The aim of this work is to investigate whether modification of carbon paper (CP) anode with graphene (GR) via layer-by-layer assembly technique is an effective approach to promote the electricity generation and methyl orange removal in MFCs. Using cyclic voltammetry and electrochemical impedance spectroscopy, the GR/CP electrode exhibited better electrochemical behavior.

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A tentative study on interaction of diclofenac sodium (DF-Na) with human serum albumin (HSA) and calf thymus DNA (ctDNA) was conducted by using multi-spectroscopic and molecular modeling techniques under simulative physiological conditions. The results of spectroscopic measurements suggested that the quenching mechanisms were static quenching. Three-dimensional fluorescence spectroscopy clearly demonstrated the occurrence of conformational changes of HSA with addition of DF-Na.

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Article Synopsis
  • The study focused on the interaction between a molecular probe (CECT) and serum albumin proteins (HSA and BSA) under biological conditions, examining how these interactions affect synchronous fluorescence spectra.
  • The method developed allows for the determination of protein concentrations in serum, showing good correlation with HSA and BSA levels, and has low detection limits.
  • The results indicate that this approach is easy to use, rapid, sensitive, and provides reliable measurements for total proteins in serum albumin samples.
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The interaction between human serum albumin (HSA) and N(6)-(2-hydroxyethyl)-adenosine (HEA) was investigated using fluorescence spectroscopy in combination with UV absorption spectroscopy for the first time. The results of spectroscopic measurements suggested that the hydrophobic interaction was the predominant intermolecular force stabilizing the complex, which was in good agreement with the results of molecular modelling study. The enthalpy change (DeltaH) and the entropy change (DeltaS) were calculated, according to the Van't Hoff equation, to be -24.

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The interactions between N-(p-chlorophenyl)-N'-(1-naphthyl) thiourea and serum albumin were investigated by fluorescence spectroscopy and UV absorption spectrum under physiological conditions. The results of spectroscopic measurements suggested that N-(p-chlorophenyl)-N'-(1-naphthyl) thiourea should have a strong ability to quench the intrinsic fluorescence of both bovine serum albumin and human serum albumin through static quenching procedure, and the hydrophobic interaction was the predominant intermolecular force stabilizing the complex. Thermodynamic parameter enthalpy changes (DeltaH) and entropy changes (DeltaS) were calculated according to the Vant'Hoff equation.

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The binding of N-(p-ethoxy-phenyl)-N'-(1-naphthyl)thiourea (EPNT) to human serum albumin (HSA) was investigated under simulative physiological conditions by fluorescence spectra in combination with UV absorption spectroscopy and a molecular modeling method. A strong fluorescence quenching reaction of EPNT to HSA was observed, and the quenching mechanism was suggested to be static quenching according to the Stern-Volmer equation. The binding constants (K) at different temperatures as well as thermodynamic parameters, enthalpy change (DeltaH) and entropy change (DeltaS), were calculated according to relevant fluorescent data and the vant' Hoff equation.

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A method for the determination of bismuth in pharmaceutical products using methyltriphenylphosphonium bromide as a molecular probe based on the resonance light scattering (RLS) technique was developed. In the presence of Tween-20, bismuth reacts with a large excess of I(-) to form [BiI(4)](-), which further reacts with methyltriphenylphosphonium bromide (MTPB) to form an ion-association compound. This resulted in a significant enhancement of RLS intensity and the appearance of the corresponding RLS spectral characteristics.

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The preparation and characteristics of N-n-undecyl-N'-(sodium-p-aminobenzenesulfonate) thiourea (UPT), a new water-soluble reagent with a saturated fatty hydrocarbon group, were described. The interactions of UPT with bovine serum albumin (BSA) and human serum albumin (HSA) were studied using fluorescence spectroscopy in combination with ultraviolet (UV) absorption spectroscopy, circular dichroism (CD) spectroscopy, Fourier transform infrared (FTIR) spectroscopy, and the molecular modeling method. UPT exhibited a strong ability to quench the intrinsic fluorescence of both BSA and HSA through a static quenching procedure.

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