Carboxymethyl Cellulose Surface Modification Alleviates the Toxicity of Fe-MOFs to Rice and Improves Iron Absorption.

Iron-based metal-organic frameworks (Fe-MOFs) are widely used for agricultural chemical delivery due to their high loading capacity, and they also have the potential to provide essential iron for plant growth. Therefore, they hold significant promise for agricultural applications. Evaluating the plant biotoxicity of Fe-MOFs is crucial for optimizing their use in agriculture.

Relationship between serum homocysteine, folate and vitamin B12 levels and cognitive function in patients with drug-naive obsessive-compulsive disorder.

The study aimed to investigate the correlation between Homocysteine (HCY), folate and vitamin B12 (VB12) levels and cognitive function in patients with drug-naive obsessive-compulsive disorder (OCD).Fifty patients with drug-naive OCD and 50 matched healthy controls recruited were enrolled. Subjects were cognitively assessed using The MATRICS Consensus Cognitive Battery (MCCB) scales.

From OCD Symptoms to Sleep Disorders: The Crucial Role of Vitamin B12.

Objective: Vitamin B12 is crucial for neurological functions and linked to various psychiatric disorders. Given its importance, this study explores the impact of vitamin B12 deficiency on sleep quality in Obsessive-Compulsive Disorder (OCD) patients, while also examining folate and homocysteine levels to explore their potential interactions with OCD symptoms and sleep quality.

Methods: This cross-sectional study included 52 patients with OCD and 42 healthy controls.

High-Throughput Single-Molecule Surface-Enhanced Raman Spectroscopic Profiling of Single-Amino Acid Substitutions in Peptides by a Gold Plasmonic Nanopore.

Simultaneous detection and structural characterization of protein variants on a single platform are highly desirable but technically challenging. Herein, we present a single-molecule spectral system based on a gold plasmonic nanopore for analyzing two peptides and their single-point mutated variants. The gold plasmonic nanopore enabled the high-throughput acquisition of surface-enhanced Raman scattering (SERS) spectra at the single-molecule level by electrically driving analytes into hot spots.

Recent Trends in Foliar Nanofertilizers: A Review.

It is estimated that 40-70%, 80-90% and 50-90% of the conventional macronutrients N, P and K applied to the soil are lost, respectively, resulting in considerable loss of resources. Compared to conventional fertilizers, nanofertilizers have the advantages of controlled release, high nutrient utilization, low cost and relatively low environmental pollution due to their small size (1-100 nm) and high specific surface area. The application of nanofertilizers is an up-and-coming field of agricultural research and is an attractive and economical substitute for common fertilizers which can boost global food productivity sustainably.

An aptamer-based colorimetric/SERS dual-mode sensing strategy for the detection of sulfadimethoxine residues in animal-derived foods.

Residues of sulfadimethoxine (SDM) in animal-derived foods have attracted widespread public concern. Herein, we propose an aptamer-based colorimetric/SERS dual-mode sensing strategy for the determination of SDM based on hexadecyl trimethyl ammonium bromide (CTAB) induced aggregation of nanoparticles. In the absence of SDM, the SDM aptamer formed a supramolecular composite with CTAB, and the 4-mercaptopyrimidine functionalized gold nanoparticles (AuNPs@4-MPY) remained dispersed due to the lack of CTAB.

Rapid determination of thiram and atrazine pesticide residues in fruit and aqueous system based on surface-enhanced Raman scattering.

In this work, a rapid and sensitive strategy was developed to determine thiram (THI) and atrazine (ATZ) by surface-enhanced Raman scattering (SERS) technology. β-cyclodextrin modified silver nanoparticles (β-CD-AgNPs) were synthesized using β-CD as a reducing agent and encapsulating agent under alkaline conditions and employed as SERS substrate. The existence of β-CD can capture the molecules to form host-guest complex and fix molecular orientation in its cavity, thus ensuring the enhanced SERS signal intensity of THI and ATZ.

Determination of antihypertensive drugs irbesartan and doxazosin mesylate in healthcare products and urine samples using surface-enhanced Raman scattering.

In this paper, a surface-enhanced Raman scattering (SERS) strategy was constructed for the determination of antihypertensive drugs irbesartan (IRB) and doxazosin mesylate (DOX). β-Cyclodextrin-capped silver nanoparticles (CD-AgNPs) are employed as SERS-active substrate. The introduction of β-CD with hydrophobic cavity can capture drug molecules to form host-guest complex, making the drug molecules closer to the electromagnetic enhancement field of the AgNPs, thereby enhancing the SERS signal of drug molecules with low Raman cross-section.

Au nanoparticles decorated covalent organic framework composite for SERS analyses of malachite green and thiram residues in foods.

A three-dimensional (3D) surface-enhanced Raman scattering (SERS) substrate composed of gold nanoparticles (AuNPs) self-assembled covalent organic frameworks (COFs) was fabricated via the electrostatic interaction between positively charged COFs and negatively charged AuNPs, which exhibited excellent SERS performance and were successfully applied for the analyses of malachite green (MG) residue in different seafood products as well as thiram residue in several kinds of fruit juice. The raspberry-like structure SERS substrate has a larger surface area that can provide more adsorption sites in testing and improve the efficiency of sample enrichment. By using this developed SERS substrate, the detection linearity ranges are 1.

Metal-organic framework modified by silver nanoparticles for SERS-based determination of sildenafil and pioglitazone hydrochloride.

A versatile surface-enhanced Raman scattering (SERS) assay has been established that can realize rapid and sensitive determination of sildenafil (SIL) and pioglitazone hydrochloride (PIO) adulteration in healthcare products. Metal-organic frameworks-silver nanoparticles (MOFs-AgNPs) with SERS activity were successfully prepared via in situ synthesis AgNPs on the MOFs surface. By virtue of the adsorptivity of MOFs, the MOFs-AgNPs could effectively concentrate the drug molecules on the electromagnetic enhancement areas of AgNPs.

Rapid determination of propylthiouracil and methimazole by surface-enhanced Raman scattering based on sodium alginate-protected silver nanoparticles.

A rapid, ultrasensitive and selective method has been established to determine antithyroid drugs [propylthiouracil (PTU) and methimazole (MTZ)] by surface-enhanced Raman scattering (SERS). Silver nanoparticles (AgNPs) were synthesized by reduction of silver nitrate (AgNO) with sodium alginate (SA) and were used as SERS substrates. Through optimization of the SERS conditions, including the volume of SA-protected AgNPs solution, pH of Britton-Robinson (BR) buffer solution and concentration of NaCl solution, linear responses were obtained for PTU and MTZ in the concentration ranges of 3.

Emissions of terbium metal-organic frameworks modulated by dispersive/agglomerated gold nanoparticles for the construction of prostate-specific antigen biosensor.

Herein, a universal and multifunctional fluorescence sensor platform is designed by the interaction of aggregation/dispersion gold nanoparticles (AuNPs) with Tb-metal-organic frameworks (Tb-MOFs). It is found that the dispersed AuNPs rather than the aggregated ones can quench effectively the fluorescence of Tb-MOFs, and the quenching process presumably involves the mechanism of inner filter effect (IFE), dynamic quenching effect (DQE), and fluorescence resonance energy transfer (FRET). The different affinities of aptamer and aptamer-target complex toward AuNPs are employed to modulate the fluorescence signal change of Tb-MOFs.