A kind of multi-dot ensemble regression AI detector for lubricating oil additive content based on lambert-beer law.

In this work, we propose a Multi-dot Ensemble Regression AI detector (MER) based on the Lambert-Beer law. We pre-trained a model using the infrared spectral data of target additives collected in advance to detect the target additives in unknown oil samples. The algorithm's feasibility was validated by assessing the content of additives in a series of simulated commercial oil samples that were not part of the training set.

Improvement of nucleotide content of Cordyceps tenuipes by Schisandra chinensis: fermentation process optimization and application prospects.

Nucleotides are important components and the main indicators for judging Cordyceps quality. In this paper, the mixed fermentation process of Schisandra chinensis and Cordyceps tenuipes was systematically studied, and it was proposed that the fermentation products aqueous extract (S-ZAE) had antioxidant activity and anti-AChE ability. Herein, the results of a single factor showed that S.

Icaritin attenuates recurrent spontaneous abortion in mice by modulating Treg/Th17 imbalance via TGF-β/SMAD signaling pathway.

Recurrent spontaneous abortion (RSA) is a challenging global issue. Although the cause is unknown, increasing evidence suggests that immunological factors play a crucial role in RSA development. Icaritin (ICT), a natural compound derived from Epimedium, has demonstrated diverse biological activities, including anti-inflammatory, anti-cancer, and immunomodulatory effects.

A survey of caregiver burden for stroke survivors in non-teaching hospitals in Western China.

The social factors that moderate stroke caregiver burden have been found to be culture- and gender-specific. We examined the factors that influence the social support and self-efficacy of caregivers of stroke survivors and the burden of caregiving in China. To determine the caregiver burden of stroke survivors, their social support, and their self-efficacy.

miR-600 promotes ovarian cancer cells stemness, proliferation and metastasis via targeting KLF9.

Previous studies have revealed that miRNAs participate in the pathogenesis of ovarian cancer; however, whether miR-600 is also involved remains unclear. In this study, we aimed to investigated the role of miR-600 in ovarian cancer progression. Here, miR-600 expression was significantly upregulated in ovarian cancer tissues and stem cells.

Tiaojing Cuyun Recipe Enhances Pregnancy Outcome via the VEGF/PI3K/AKT/eNOS Signaling Pathway in EID Mice.

Purpose: In this study, we evaluated the effect of Tiaojing Cuyun Recipe (TJCYR) on embryo implantation dysfunction- (EID-) induced damage of endometrial receptivity in mice and investigated the mechanisms underlying the effect.

Methods: The main compounds of TJCYR were identified by high-performance liquid chromatography (HPLC). One hundred and twenty pregnant mice were randomly divided into six groups: control, EID only, progesterone (Prog)+EID, TJCYR-low-dose+EID, TJCYR-medium-dose+EID, and TJCYR-high-dose+EID.

3D Printing of Photocuring Elastomers with Excellent Mechanical Strength and Resilience.

Three-dimensional (3D) printing elastomers, as a combination of transformative technology and widely used materials, have received great demand in many fields. However, commercial photocuring elastomer inks for 3D printing usually exhibit poor mechanical strength, inferior resilience, and lower elongation at break. In this study, photocuring inks that can be employed for digital light processing 3D printing are developed with acryloyl-modified polyethylene glycol (Acryl@PEG).

Roles of aging in the production of light-flavored Daqu.

Daqu, a complex starting material used for Baijiu production, contains microorganisms, enzymes, and volatile compounds. An important part of Daqu production is aging, but the physicochemical and microbial changes during aging remain largely unknown. This study characterized aging according to physicochemical parameters, volatile compounds, and microbial communities.

[Role of nicotinamide vadenine dinucleotide phosphate oxidase 4 in transforming growth factor-β-induced A549 cell migration].

Objective: To explore the role of NADPH oxidase 4( NOX4) in transforming growth factor-β( TGF-β)-induced A549 cells migration.

Methods: The A549 cells were allocated into five groups: TGF-β( stimulation) group, Normal control group, DPI( NOX4 inhibitor) group, TGF-β + DPI group, and DMSO( solvent control)group. The level of ROS were detected by flow cytometry instrument.

S-adenosyl methionine regulates calcium channels and inhibits uterine smooth muscle contraction in rats with infectious premature delivery through the transient receptor protein 3/protein kinase Cβ/C-kinase-activated protein phosphatase-1 inhibitor of 17 kDa signaling pathway.

The aim of the present study was to investigate the effects of S-adenosyl methionine (SAMe) on infectious premature inflammatory factors and uterine contraction, and to further explore its mechanism of action via the transient receptor protein 3 (TRPC3)/protein kinase Cβ (PKCβ)/C-kinase-activated protein phosphatase-1 inhibitor of 17 kDa (CPI-17) signaling pathway, following intervention by a TRPC3 inhibitor. A rat model of premature delivery induced by lipopolysaccharide (LPS) was established. Following treatment with SAMe and inhibiting TRPC3 expression, rat serum and uterus were isolated.

Cryptotanshinone reverses reproductive disturbances in rats with dehydroepiandrosterone-induced polycystic ovary syndrome.

Polycystic ovarian syndrome (PCOS), with a prevalence of 5-8%, is the most common endocrine disorder in women of reproductive age. Although cryptotanshinone (CRY) has been shown to effectively reverse reproductive disturbances, it remains poorly understood whether it can be used to treat PCOS. Here we used an established rat model of PCOS.

Paeoniflorin improves menopause depression in ovariectomized rats under chronic unpredictable mild stress.

Paeoniflorin has been shown to effectively relieve neurologic impairments and lessen depression. It remains poorly understood whether it can be used to treat menopause depression; therefore, in the present study, animal model of menopause depression were established by resecting the ovaries in combined with long-term chronic unpredictable stress. Animal model of menopause depression was established by ovariectomy.

Noncovalent microcontact printing for grafting patterned polymer brushes on graphene films.

This article describes a simple and universal approach to prepare patterned polymer brushes on graphene-based substrate surfaces by microcontact printing (μCP) of initiator molecules and subsequent surface initiated atom transfer radical polymerization (SI-ATRP) method. Four different initiators are designed and have strong adhesion with graphene-based substrates through noncovalent interaction. Optical and fluorescence microscopy, atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS) were used to characterize the successful polymerization of vinyl monomers on substrate surfaces.

Imidazolium ionic liquids as antiwear and antioxidant additive in poly(ethylene glycol) for steel/steel contacts.

Three imidazolium-based ionic liquids containing sterically hindered phenol groups were synthesized. The cation was 1-(3,5-ditert-butyl-4-hydroxybenzyl)-3-methyl-imidazolium, and the anions were tetrafluoroborates, hexafluorophosphates, and bis(trifluoromethylsulfonyl)imide. The physical properties of the synthetic products and of poly(ethylene glycol) (PEG) with the additive were evaluated.

Bisimidazolium ionic liquids as the high-performance antiwear additives in poly(ethylene glycol) for steel-steel contacts.

Bisimidazolium ionic liquids [C(10)(m(2)im)(2)(NTf(2))(2), C(10)(m(2)im)(2)(PF(6))(2), and C(10)(m(2)im)(2)(BF(4))(2)] with different anions were evaluated as the antiwear additives in poly(ethylene glycol) at room temperature. Results showed that they could effectively reduce the friction and wear of sliding pairs compared with the cases without these additives. Especially, C(10)(m(2)im)(2)(NTf(2))(2) showed better antiwear properties with an optimum concentration of 3 wt %, by which a significant improvement of its antiwear property by dozens of times with respect to the base oil was achieved.

Aucubin prevents loss of hippocampal neurons and regulates antioxidative activity in diabetic encephalopathy rats.

In this study, the neuroprotection of aucubin and its mechanism were evaluated in the rat model of diabetic encephalopathy. Diabetes mellitus (DM) rats were stratified by cognitive capability (CC), and assigned to four treatment groups for aucubin treatment (doses of 0, 1, 5 or 10 mg/kg aucubin), with a further two groups of non-DM rats ranked by CC as controls for aucubin (doses of 0 or 5 mg/kg aucubin). Neuroprotection was estimated by the indexes of behavior and histology.

Neuroprotection of aucubin in primary diabetic encephalopathy.

Hippocampal neuronal apoptosis accompanied by impairment of cognitive function occurs in primary diabetic encephalopathy. In this study, we investigated the neuroprotective mechanism of the iridoid glycoside, aucubin, using rats (n=8). Diabetes mellitus was induced in the rats by intraperitoneal (i.

The potentiation of curcumin on insulin-like growth factor-1 action in MCF-7 human breast carcinoma cells.

Curcumin has anticarcinogenic and chemopreventive properties in a variety of experimental cancer models. Our in vitro studies have shown that curcumin inhibits cell growth and induces apoptosis in MCF-7, a human breast carcinoma cell line. The insulin-like growth factor-1 (IGF-1) system, including IGFs (IGF-1 and IGF-2), IGF-1R (IGF-1 receptor) and IGFBPs (IGF binding proteins), has been implicated to play a critical role in the development of breast cancer.