Preoperative CT and Radiomics Nomograms for Distinguishing Bronchiolar Adenoma and Early-Stage Lung Adenocarcinoma.

Rationale And Objectives: Evaluating the capability of CT nomograms and CT-based radiomics nomograms to differentiate between Bronchiolar Adenoma (BA) and Early-stage Lung Adenocarcinoma (LUAD).

Materials And Methods: In this retrospective study; we analyzed data from 226 patients who were treated at our institution and pathologically confirmed to have either BA or Early-stage LUAD. Patients were randomly divided into a training cohort (n=158) and a testing cohort (n=68).

Field attenuation characteristics of hearing protectors and differences in estimating their attenuation with different methods.

This study investigated the field attenuation characteristics of hearing protection devices (HPDs), differences in estimating the protection provided by HPDs with different rating methods, and suggested potential solutions on proper use of attenuation ratings to estimate the protection provided by HPDs. The binaural octave-band personal attenuation values obtained from 1583 field users with 3985 fits on seven HPDs were used to compute the field-rating values as described in the International Organization for Standardization standard ISO 4869-2:2018, and the octave-band noise reduction (OB NR) values of each fit for 100 noises. The estimated protection for 100 noises was compared within different rating methods.

Occupational Mercury Exposure at a Thermometer Facility - Jiangsu Province, 2019.

What Is Already Known About This Topic?: Mercury is still used in the manufacture of some thermometers in China. This may pose health risks if exposure is not properly prevented and controlled.

What Is Added By This Report?: An onsite investigation of a workplace at a thermometer facility in Jiangsu Province in 2019 found heavily elevated airborne and urinary mercury levels among a massive number of workers exposed to mercury.

The effect of a psychological nursing intervention program based on the "Timing it Right" (TIR) framework on elderly patients' anxiety, psychology, and self-efficacy.

Objective: To investigate the occurrence of anxiety and depression in elderly patients and to explore the effect of a psychological nursing intervention program based on the "Timing it Right" framework on the anxiety, depression, and self-efficacy among elderly patients.

Methods: 135 elderly patients admitted to our hospital were divided into two groups. The 69 patients in the experimental group underwent systematic psychological intervention, and the 66 patients in the control group were given only general psychological support.

Concentration Distribution and Analysis of Urinary Glyphosate and Its Metabolites in Occupationally Exposed Workers in Eastern China.

: There are few published studies concerning occupational exposure to glyphosate (GLY), and these are limited to spraying, horticulture and other agricultural aspects. Therefore, the concentration of glyphosate and its metabolite aminomethylphosphonic acid (AMPA), in the urine of workers exposed to glyphosate during glyphosate production was determined, and the relationship between internal (urinary glyphosate and AMPA concentration) and external exposure dose (time weighted average (TWA) value of glyphosate in the air of workplace) was analyzed. : To avoid the influence of preparations, we selected people who were only involved in GLY production (without exposure to its preparations) as our research subjects.

Genetic variation in GSTM1 is associated with susceptibility to noise-induced hearing loss in a Chinese population.

Objectives: To investigate whether glutathione S-transferases (GST) genetic polymorphisms (GSTT1 rs1049055, GSTM1 rs10712361, and GSTP1 rs1695) are associated with susceptibility to noise-induced hearing loss (NIHL).

Methods: These polymorphisms were analyzed in 444 NIHL and 445 normal hearing workers. In addition, total plasma GST activity was measured in all subjects.

[JWA regulates N-methyl-N'-nitro-N-nitrosoguanidine induced malignant transformation in human bronchial epithelial cells].

Objective: To investigate the role and possible mechanism of JWA in N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) inducing human bronchial epithelial (HBE) cells' neoplastic transformation.

Methods: JWA overexpression vector and its stable transfection HBE cells were established. The characteristics of transformed HBE cells were determined by methyl thiazolyl tetrazolium (MTT) assay and the soft agar colony formation assay.

[The role of JWA in N-methyl-N'-nitro-N-nitrosoguanidine induced human bronchial epithelial cell apoptosis].

Objective: To investigate the role and possible mechanism of JWA in N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) induced human bronchial epithelial (HBE) cell apoptosis.

Methods: The cell growth inhibition rate was detected by MTT, the cell apoptosis was measured by Hoechst staining, the expression of JWA protein was detected by Western blot, and the potential binding protein of JWA proximal promoter was detected by Southwestern assay.

Results: MNNG treatment of HBE cells for 24 hours induced apoptosis with significant dose-effect relationship and in this course the expression of JWA protein was elevated.