Prediction of posthepatectomy liver failure in patients with hepatocellular carcinoma through ultrasound elastography.

In this article, we comment on the article by Cheng published in recently. Posthepatectomy liver failure (PHLF) remains a leading cause of hepatectomy-related mortality and can be evaluated according to liver reserve function. Liver stiffness (LS) measured by ultrasonic elastography and spleen area demonstrate a strong correlation with hepatic proliferation, fibrosis, and portal vein congestion, thus indirectly reflecting liver reserve function.

Radiomics-based nomogram for predicting total knee replacement in knee osteoarthritis patients.

Background: The incidence of total knee replacement (TKR) surgeries has increased, partly attributed to healthcare policies that cause premature and potentially unwarranted interventions. This has raised concerns regarding a potential trend of excessive surgeries.

Purpose: This study aimed to propose a predictive model based on digital radiography (DR) radiomics to objectively assess the need for TKR surgery in patients with knee osteoarthritis (KOA) and to improve risk stratification, thereby avoiding unnecessary surgeries.

Shedding Light on Hadronization by Quarkonium Energy Correlator.

We propose to measure the energy correlator in quarkonium production, which tracks the energy deposited in the calorimeter at the χ-angular distance away from the identified quarkonium. The observable eliminates the need for jets while sustaining the perturbative predictive power. Analyzing the power correction to the energy correlator, we demonstrate that the novel observable supplies a unique gateway to probing the hadronization, especially when cosχ≳0 in the quarkonium rest frame, where the perturbative emissions are depleted due to the dead-cone effects.

pH monitoring in high ionic concentration environments: performance study of graphene-based sensors.

Graphene-based pH sensors, acclaimed for their exceptional sensitivity to environmental variations, have garnered significant interest in scientific research. However, the sensor performance in high ionic concentration environments is limited, due to the Debye length ion screening effect. In this study, an innovative graphene channel pH sensing device was developed and modified by cross-linked poly(methyl methacrylate) (PMMA).

Intratumoral and peritumoral radiomics combined with computed tomography features for predicting the invasiveness of lung adenocarcinoma presenting as a subpleural ground-glass nodule with a consolidation-to-tumor ratio ≤50.

Background: Preoperative accurate judgment of the degree of invasiveness in subpleural ground-glass lung adenocarcinoma (LUAD) with a consolidation-to-tumor ratio (CTR) ≤50% is very important for the choice of surgical timing and planning. This study aims to investigate the performance of intratumoral and peritumoral radiomics combined with computed tomography (CT) features for predicting the invasiveness of LUAD presenting as a subpleural ground-glass nodule (GGN) with a CTR ≤50%.

Methods: A total of 247 patients with LUAD from our hospital were randomly divided into two groups, i.

CT-based whole lung radiomics nomogram for identification of PRISm from non-COPD subjects.

Background: Preserved Ratio Impaired Spirometry (PRISm) is considered to be a precursor of chronic obstructive pulmonary disease. Radiomics nomogram can effectively identify the PRISm subjects from non-COPD subjects, especially when during large-scale CT lung cancer screening.

Methods: Totally 1481 participants (864, 370 and 247 in training, internal validation, and external validation cohorts, respectively) were included.

Brushy C-Decorated BiTe-Based Thermoelectric Film for Efficient Photodetection and Photoimaging.

Current strategies for simultaneously achieving high thermoelectric performance and high light absorption efficiency still suffer from complex steps and high costs. Herein, two kinds of amorphous thermoelectric films of n-type BiTe and p-type BiSbTe with high Seebeck coefficients were prepared by pulsed laser deposition (PLD) technology. In addition, C-decorated films with excellent light absorption efficiency at the junction of the thermoelectric legs were prepared by simple drop coating and reactive ion etching (RIE) method.

Antidepressant Effect and Mechanism of Essential Oil on Reserpine-Induced Depression Model Mice.

The disturbance of brain biochemical substances serves as a primary cause and aggravating factor of depression. This study aimed to investigate the principal components of and its effect on reserpine-induced depression mice,w ith its relationship with brain central transmitters and related proteins. The main constituents of essential oil (PMEO) were analyzed by GC-MS spectrometry.

Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway.

Unlabelled: Macrophage efferocytosis, the process by which phagocytes engulf and remove apoptotic cells (ACs), plays a critical role in maintaining tissue homeostasis. Efficient efferocytosis prevents secondary necrosis, mitigates chronic inflammation, and impedes atherosclerosis progression. However, the regulatory mechanisms of efferocytosis under atherogenic conditions remain poorly understood.

A clinical-radiomics nomogram based on automated segmentation of chest CT to discriminate PRISm and COPD patients.

Purpose: It is vital to develop noninvasive approaches with high accuracy to discriminate the preserved ratio impaired spirometry (PRISm) group from the chronic obstructive pulmonary disease (COPD) groups. Radiomics has emerged as an image analysis technique. This study aims to develop and confirm the new radiomics-based noninvasive approach to discriminate these two groups.

Electroweak Corrections to Double Higgs Production at the LHC.

We present the results for the complete next-to-leading order electroweak corrections to pp→HH at the Large Hadron Collider, focusing on the dominant gluon-gluon fusion process. While the corrections at the total cross-section level are approximately -4%, those near the energy of HH production threshold exceed +15%, and corrections at the high-energy region are around -10%, leading to a shape distortion for the differential distributions. Our findings substantially diminish the theoretical uncertainties associated with this pivotal process, providing valuable input for understanding the shape of the Higgs boson potential upon comparison with experimental measurements.

Nomogram using intratumoral and peritumoral radiomics for the preoperative prediction of visceral pleural invasion in clinical stage IA lung adenocarcinoma.

Background: Accurate prediction of visceral pleural invasion (VPI) in lung adenocarcinoma before operation can provide guidance and help for surgical operation and postoperative treatment. We investigate the value of intratumoral and peritumoral radiomics nomograms for preoperatively predicting the status of VPI in patients diagnosed with clinical stage IA lung adenocarcinoma.

Methods: A total of 404 patients from our hospital were randomly assigned to a training set (n = 283) and an internal validation set (n = 121) using a 7:3 ratio, while 81 patients from two other hospitals constituted the external validation set.

Heavy-Quark Pair Production at Lepton Colliders at NNNLO in QCD.

We compute the total cross section and invariant mass distribution for heavy-quark pair production in e^{+}e^{-} annihilation at the next-to-next-to-next-to-leading order in QCD. The obtained results are expressed as piecewise functions defined by several deeply expanded power series, facilitating a rapid numerical evaluation. Utilizing top-pair production at a collision energy of 500 GeV as a benchmark, we observe a correction of approximately 0.

CT whole lung radiomic nomogram: a potential biomarker for lung function evaluation and identification of COPD.

Background: Computed tomography (CT) plays a great role in characterizing and quantifying changes in lung structure and function of chronic obstructive pulmonary disease (COPD). This study aimed to explore the performance of CT-based whole lung radiomic in discriminating COPD patients and non-COPD patients.

Methods: This retrospective study was performed on 2785 patients who underwent pulmonary function examination in 5 hospitals and were divided into non-COPD group and COPD group.

Progress of MRI in predicting the circumferential resection margin of rectal cancer: A narrative review.

Rectal cancer (RC) is the third most frequently diagnosed cancer worldwide, and the status of its circumferential resection margin (CRM) is of paramount significance for treatment strategies and prognosis. CRM involvement is defined as tumor touching or within 1 mm from the outermost part of tumor or outer border of the mesorectal or lymph node deposits to the resection margin. The incidence of involved CRM varied from 5.

Multi-instance learning based lung nodule system for assessment of CT quality after small-field-of-view reconstruction.

Small-field-of-view reconstruction CT images (sFOV-CT) increase the pixel density across airway structures and reduce partial volume effects. Multi-instance learning (MIL) is proposed as a weakly supervised machine learning method, which can automatically assess the image quality. The aim of this study was to evaluate the disparities between conventional CT (c-CT) and sFOV-CT images using a lung nodule system based on MIL and assessments from radiologists.

Myosin light chain 6 (Myl6) interacts with kindlin-3 and is required to support integrin αβ activation in platelets in mice.

Background: Kindlin-3 in platelets plays an essential role in supporting integrin αβ activation, platelet spreading, aggregation, and clot retraction by binding to the integrin β cytoplasmic tail. However, the mechanism by which kindlin-3 mediates the crosstalk between integrin αβ and myosin in platelets remains unknown.

Objectives: To examine the role of myosin light chain 6 (Myl6) in supporting integrin αβ activation in platelets.

An integrative clinical and CT-based tumoral/peritumoral radiomics nomogram to predict the microsatellite instability in rectal carcinoma.

Background: Microsatellite instability (MSI) is detected in approximately 15% of colorectal carcinoma (CRC) patients, which has emerged as a predictor of patient response to adjuvant chemotherapy. Rectal carcinoma (RC) is the most common type of CRC. Therefore, prediction of MSI status of RC is significant for personalized medication.

A novel leukocyte adhesion deficiency type III mutation manifests functional importance of the compact FERM domain in kindlin-3.

Background: Leukocyte adhesion deficiency III (LAD-III) is a rare autosomal recessive syndrome characterized by functional deficiencies of platelets and leukocytes that occurs due to mutations in the FERMT3 gene encoding kindlin-3. Kindlin-3 is a FERM domain-containing adaptor protein that is essential in integrin activation. We have previously demonstrated that the FERM domain of kindlin-3 is structurally compact and plays an important role in supporting integrin activation in a mouse model.

Antibacterial activity and mechanism of cinnamon essential oil nanoemulsion against CM2.

This work aimed to evaluate the antibacterial activity and mechanism of cinnamon essential oil nanoemulsion (CON) against CM2. The results revealed that CON could effectively inhibit the proliferation of . CM2 cells in a time- and concentration-dependent manner.