Poloxamer 407 modified collagen/β-tricalcium phosphate scaffold for localized delivery of alendronate.

Systemic administration of alendronate is associated with various adverse reactions in clinical settings. To mitigate these side effects, poloxamer 407 (P-407) modified with cellulose was chosen to encapsulate alendronate. This drug-loaded system was then incorporated into a collagen/β-tricalcium phosphate (β-TCP) scaffold to create a localized drug delivery system.

Tuning Electrocatalytic Activities of Dealloyed Nanoporous Catalysts by Macroscopic Strain Engineering.

It is technically challenging to quantitatively apply strains to tune catalysis because most heterogeneous catalysts are nanoparticles, and lattice strains can only be applied indirectly via core-shell structures or crystal defects. Herein, we report quantitative relations between macroscopic strains and hydrogen evolution reaction (HER) activities of dealloyed nanoporous gold (NPG) by directly applying macroscopic strains upon bulk NPG. It was found that macroscopic compressive strains lead to a decrease, while macroscopic tensile strains improve the HER activity of NPG, which is in line with the -band center model.

Dual Redox Reaction Sites for Pseudocapacitance Based on Ti and -P Functional Groups of TiCPBr MXene.

MXenes have extensive applications due to their different properties determined by intrinsic structures and various functional groups. Exploring different functional groups of MXenes leads to improved performance or potential applications. In this work, we prepared new TiCPBr (x=0.

Improved hydrogen evolution performance of Ni-based nanoporous catalyst with Mo and B co-addition.

The exploration of efficient and stable noble-metal-free electrocatalysts for hydrogen evolution reaction (HER) is of great interest for the development of electrochemical hydrogen production technologies. Herein, nanoporous Ni-based catalyst with Mo and B co-addition (NiMoB) prepared by dealloying is reported as an efficient electrocatalysts for HER. The nanoporous NiMoB achieves an overpotential of 31 mV at 10 mA cm, along with exceptional catalytic stability in alkaline electrolyte.

[Near-infrared excited graphene oxide/silver nitrate/chitosan coating for improving antibacterial properties of titanium implants].

Objective: To design and construct a graphene oxide (GO)/silver nitrate (AgPO)/chitosan (CS) composite coating for rapidly killing bacteria and preventing postoperative infection in implant surgery.

Methods: GO/AgPO composites were prepared by ion exchange method, and CS and GO/AgPO composites were deposited on medical titanium (Ti) sheets successively. The morphology, physical image, photothermal and photocatalytic ability, antibacterial ability, and adhesion to the matrix of the materials were characterized.

Effect of Platelet-Rich Plasma Addition on the Chemical Properties and Biological Activity of Calcium Sulfate Hemihydrate Bone Cement.

Currently, platelet-rich plasma (PRP) is an attractive additive for bone repair materials. PRP could enhance the osteoconductive and osteoinductive of bone cement, as well as modulate the degradation rate of calcium sulfate hemihydrate (CSH). The focus of this study was to investigate the effect of different PRP ratios (P1: 20 vol%, P2: 40 vol%, and P3: 60 vol%) on the chemical properties and biological activity of bone cement.

Flexible free-standing antibacterial nanoporous Ag ribbon.

The biomedical field has the potential to significantly benefit from the use of flexible free-standing Ag nanostructures due to their outstanding mechanical and antibacterial properties. However, the intricate process of synthesizing these nanostructures, as well as the potential toxicity of nanostructured Ag, pose significant challenges. This study used a facile etching method to synthesize the free-standing nanoporous Ag (NP-Ag) ribbons with a homogeneous and bicontinuous three-dimensional ligament structure.

Engineering Dynamic Defect of Ce /Ce -Based Metal-Organic Framework through Ultrasound-Triggered Au Electron Trapper for Sonodynamic Therapy of Osteomyelitis.

Defect engineering is an important way to tune the catalytic properties of metal-organic framework (MOF), yet precise control of defects is difficult to achieve. Herein, a cerium-based MOF (CeTCPP) is decorated with Au nanoparticles. Under ultrasound irradiation, Au nanoparticles can precisely turn 1/3 of the pristine Ce nodes into Ce .

Nb-Doped TiO with Outstanding Na/Mg-Ion Battery Performance.

The group "beyond Li-ion" batteries (Na/Mg-ion batteries) have the advantages of abundant reserves and high theoretical specific capacity. However, the sluggish kinetics resulting from large ion radius (Na) and polarity (Mg) seriously limit the battery performance. Herein, we prepared Nb-doped anatase TiO with Ti vacancies (Nb-TiO) through a simple solvothermal and subsequent calcination process.

Alloying-Triggered Phase Engineering of NiFe System via Laser-Assisted Al Incorporation for Full Water Splitting.

It is challenging to design one non-noble material with balanced bifunctional performance for hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) for commercial sustainability at a low cost since the different electrocatalytic mechanisms are not easily matchable for each other. Herein, a self-standing hybrid system Ni Fe Al , consisting of Ni Al and Ni Fe phases, was constructed by laser-assisted aluminum (Al) incorporation towards full water splitting. It was found that the incorporation of Al could effectively tune the morphologies, compositions and phases.

Synthesis and water splitting performance of FeCoNbS bifunctional electrocatalyst.

Transition metal (TM) sulfides are promising catalysts for water splitting in alkaline media due to their high intrinsic activities and similar TM-S electronic structure with hydrogenase. In this work, the nanoporous FeCoNbS electrocatalyst with nanosheet morphology is synthesized through dealloying AlFeCoNb alloy followed by the steam sulphurization. The introduction of S element improves the electronic structure, further increases the active sites, regulates the mass transfer and enhances the intrinsic activity.

Self-Driven Electron Transfer Biomimetic Enzymatic Catalysis of Bismuth-Doped PCN-222 MOF for Rapid Therapy of Bacteria-Infected Wounds.

In this work, a biomimetic nanozyme catalyst with rapid and efficient self-bacteria-killing and wound-healing performances was synthesized. Through an reduction reaction, a PCN-222 metal organic framework (MOF) was doped with bismuth nanoparticles (Bi NPs) to form Bi-PCN-222, an interfacial Schottky heterojunction biomimetic nanozyme catalyst, which can kill 99.9% of ().

Modification and evaluation of diatrizoate sodium containing polymethyl methacrylate bone cement.

Polymethyl methacrylate (PMMA) bone cement is now widely used in percutaneous vertebro plasty (PVP) and percutaneous kyphoplasty (PKP). However, studies showed that the radiopacifiers (zirconia, barium sulfate, etc.) added to PMMA will have a negative impact on its use, e.

Rapid Ferroelectric-Photoexcited Bacteria-Killing of BiTiO/TiCT Nanofiber Membranes.

Unlabelled: In this study, an antibacterial nanofiber membrane [polyvinylidene fluoride/BiTiO/TiCT (PVDF/BTO/TiCT )] is fabricated using an electrostatic spinning process, in which the self-assembled BTO/TiCT heterojunction is incorporated into the PVDF matrix. Benefiting from the internal electric field induced by the spontaneously ferroelectric polarization of BTO, the photoexcited electrons and holes are driven to move in the opposite direction inside BTO, and the electrons are transferred to TiCT across the Schottky interface. Thus, directed charge separation and transfer are realized through the cooperation of the two components.

ALD-induced TiO/Ag nanofilm for rapid surface photodynamic ion sterilization.

The daily life of people in the intelligent age is inseparable from electronic device, and a number of bacteria on touch screens are increasingly threatening the health of users. Herein, a photocatalytic TiO/Ag thin film was synthesized on a glass by atomic layer deposition and subsequent in situ reduction. Ultraviolet-visible (UV-Vis) spectra showed that this film can harvest the simulated solar light more efficiently than that of pristine TiO.

Treating Multi-Drug-Resistant Bacterial Infections by Functionalized Nano-Bismuth Sulfide through the Synergy of Immunotherapy and Bacteria-Sensitive Phototherapy.

Owing to its flexibility and high treatment efficiency, phototherapy is rapidly emerging for treating bacteria-induced diseases, but how to improve the sensitivity of bacteria to reactive oxygen species (ROS) and heat simultaneously to kill bacteria under mild conditions is still a challenge. Herein, we designed a NIR light catalyst (BiS--nitrosothiol-acetylcholine (BSNA)) by transforming O into peroxynitrite , which can enhance the bacterial sensibility to ROS and heat and kill bacteria under a mild temperature. The transformed peroxynitrite possessed a stronger ability to penetrate cell membranes and antioxidant capacity.

Magnetic Composite Rapidly Treats Staphylococcus aureus-Infected Osteomyelitis through Microwave Strengthened Thermal Effects and Reactive Oxygen Species.

It is difficult to effectively treat bacterial osteomyelitis using photothermal therapy or photodynamic therapy due to poor penetration of light. Here, a microwave (MW)-excited magnetic composite of molybdenum disulfide (MoS ) / iron oxide (Fe O ) is reported for the treatment of bacteria-infected osteomyelitis. In in vitro and in vivo experiments, MoS /Fe O is shown to effectively eradicate bacteria-infected mouse tibia osteomyelitis, due to MW thermal enhancement and reactive oxygen species (ROS) ( O and ·O ) production under MW radiation.

A Three-Dimensional Cement Quantification Method for Decision Prediction of Vertebral Recompression after Vertebroplasty.

Objective: Proposing parameters to quantify cement distribution and increasing accuracy for decision prediction of vertebroplasty postoperative complication.

Methods: Finite element analysis was used to biomechanically assess vertebral mechanics ( = 51) after percutaneous vertebroplasty (PVP) or kyphoplasty (PKP). The vertebral space was divided into 27 portions.

Simultaneously enhancing the photocatalytic and photothermal effect of NH-MIL-125-GO-Pt ternary heterojunction for rapid therapy of bacteria-infected wounds.

Infections caused by bacteria threaten human health, so how to effectively kill bacteria is an urgent problem. We therefore synthesized a NH-MIL-125-GO-Pt ternary composite heterojunction with graphene oxide (GO) and platinum (Pt) nanoparticles co-doped with metal-organic framework (NH-MIL-125) for use in photocatalytic and photothermal synergistic disinfection under white light irradiation. Due to the good conductivity of GO and the Schottky junction between Pt and MOF, the doping of GO and Pt will effectively separate and transfer the photogenerated electron-hole pairs generated by NH-MIL-125, thereby effectively improving the photocatalytic efficiency of NH-MIL-125.

High-performance five-ring-fused organic semiconductors for field-effect transistors.

Organic molecular semiconductors have been paid great attention due to their advantages of low-temperature processability, low fabrication cost, good flexibility, and excellent electronic properties. As a typical example of five-ring-fused organic semiconductors, a single crystal of pentacene shows a high mobility of up to 40 cm V s, indicating its potential application in organic electronics. However, the photo- and optical instabilities of pentacene make it unsuitable for commercial applications.