Calcium phosphate cement with minocycline hydrochloride-loaded gelatine microspheres for peri-implantitis treatment.

Objectives: This study aimed to fabricate an antibacterial calcium phosphate cement (CPC) with minocycline hydrochloride (MINO)-loaded gelatine microspheres (GMs) as a local drug delivery system for the treatment of peri‑implantitis.

Methods: CPC/GMs(MINO), incorporating MINO-loaded GMs into CPC, was developed and characterised using scanning electron microscopy (SEM), X-ray diffraction (XRD), and drug release profiling. The antibacterial activity against Porphyromonas gingivalis and Fusobacterium nucleatum was evaluated.

Naringin Release from a Nano-Hydroxyapatite/Collagen Scaffold Promotes Osteogenesis and Bone Tissue Reconstruction.

Bone fractures and defects are a major health issue and have reportedly affected over 455 million individuals globally to date. Bone tissue engineering has gained great success in bone defect repair and bone reconstruction based on the use of nano-hydroxyapatite (nHA) or collagen (COL). Both nHA and COL exhibit osteogenic induction capacity to support bone tissue regeneration; however, the former suffers from poor flexibility and the latter lacks mechanical strength.

Osteogenic growth peptide (OGP)-loaded amphiphilic peptide (NapFFY) supramolecular hydrogel promotes osteogenesis and bone tissue reconstruction.

Efficient bone reconstruction after bone injury remains a great challenge. Injectable supramolecular hydrogels based on amphiphilic peptide have been widely used due to their good biocompatability, non-immunogenicity, and manipulable physicochemical properties by sequence design. Herein, we used a well-studied hydrogelator, NapFFY, to coassemble with osteogenic growth peptide (OGP) to prepare a supramolecular hydrogel, NapFFY-OGP.

Effects of Rhein-8-O-β-D-glucopyranoside on the Biofilm Formation of Streptococcus mutans.

Dental caries is the most frequent biofilm-related human infectious disease in the oral cavity. Streptococcus mutans is one of the primary etiological agents of dental caries. The aim of our study was to investigate the effects of rhein-8-O-β-D-glucopyranoside (Rg) on the development of S.

[Effect of Pinus massoniana needle extract on root dentin demineralization in vitro].

Objective: This study aims to evaluate the effects of Pinus massoniana needle extract (PMNE) on inhibiting demineralization of root dentin.

Methods: Root dentin blocks were randomly divided into distilled deionized water (DDW) group, fluoride sodium (NaF) group, and 4%, 8% and 12% PMNE groups according to the experimental solution used in the process of pH cycling in each group. All specimens in each group experienced pH cycling for 8 d.

[Changes in expression of phospholipase C-gamma1(tyr783) in young rat condylar cartilage during functional mandibular protraction].

Objective: To investigate the changes in the expression of phospholipase C-gamma1tyr783 (PLC-γ1tyr783) in the condylar cartilage of a young rat during functional mandibular protraction. This work also explores the function of PLC-γ1tyr783 in the rat mandibular condylar cartilage bone remodeling, which could provide experimental evidence for clinical bone ortho- pedic work.

Methods: A total of 60 four-week-old male Sprague-Dawley (SD) rats were used in this study.

[Longitudinal survey and analysis among Chengdu residents on cognition and acceptance of implant dentures].

Objective: This study aims to survey the cognition and acceptance of implant dentures among Chengdu residents in 2005 and 2013 and to comparatively analyze the differences and influencing factors.

Methods: A questionnaire was designed for this study. Its main content included basic demographics of respondents (gender, age, cultural level, and income level), cognition level of implant dentures (concept and main characteristics of implant dentures), main concern of respondents regarding implant dentures and medical institutions, and acceptance level of the price of implant dentures, among others.

[Soft tissue changes following the treatment of Class II division 1 malocclusion using Headgear-activator appliance].

Purpose: To investigate the soft tissue changes following the treatment of Class II division 1 malocclusion using Headgear-activator appliance.

Methods: Fifty Class II division 1 malocclusion subjects who were at peak high velocity on the growth curve were divided into two groups. Standardized lateral cephalogram was taken for each patient in the two groups before and after treatment.

[Hard and soft tissue changes following the treatment of Class II division 1 malocclusion using twin-block appliance].

Objective: To investigate the hard and soft tissue changes following the treatment of Class II division 1 malocclusion using Twin-block appliance.

Methods: 50 Class II division 1 malocclusion subjects whose handwrist radiographs were in FG-G stage were selected. One group (27 patients) was treated with Twin-block appliance, the other group (23 patients) was observed without treatment The acquired data of cephalometric of two groups were analyzed statistically with SPSS 11.

[Bone histomorphometry study in agglutination of femoral condyle of dog after being compressed].

Objective: This study simulated clinical implant surgery using squeeze technique by establishing a rational animal model. To measure the morphologic parameters in order to observe the agglutination of the cancellous bone after being compressed. The study wanted to get some favourable support of implant squeeze technique in bone healing and obtaining primary stabilities of implants, so as to provide some reasonable and valid guidance in the application and improvement of implant squeeze technique.

[Effect of early treatment with the Twin-block appliance].

Objective: To evaluate the effectiveness of early treatment with the Twin-block appliance for the developing Class II division 1 malocclusion.

Methods: A Total of 30 children with Class II division 1 malocclusion, 18 (8 male, 10 female) out of which received treatment with the Twin-block appliance, the other 12 cases (6 male, 6 female) without treatment served as control group. Cephalometric data were collected at the start and the end of the study and statistical analysis were applied.