Publications by authors named "Yanping Zhang"

Objective: Explore the application effects of "Internet +" continuous emotional management training in depression patients and analyze the feasibility of innovative rehabilitation training methods.

Methods: Conveniently selected 100 discharged patients meeting the diagnostic criteria for depression from the Second Affiliated Hospital of Xinxiang Medical University between August 2022 and January 2023 as study subjects. They were divided into an intervention group and a control group according to their discharge time, with 50 patients in each group.

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Polystyrene micro- and nanoplastics (MNPs) are increasingly found in terrestrial environments, posing risks across the food web. However, the potential impacts of MNPs transfer on plant-insect interactions remains largely unknown. In this study, consumption of willow plants (Salix maizhokunggarensis) exposed to 10.

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Accurate determination of pesticide residues is crucial for food safety. A self-calibration method was developed for dual-signal "naked-eye" detection of organophosphorus pesticides (OPs) using bifunctional gold nanozymes (AuNEs). OPs inhibit the cascade reaction of acetylcholinesterase/choline oxidase (AChE/CHO) to reduce hydrogen peroxide (HO) production, which affects the AuNE-catalyzed color reaction and quenches the fluorescence of AuNEs with the assistance of Fe.

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Purpose: Currently, detethering surgery (DS) is the modality most extensively utilized to treat primary Tethered cord syndrome (TCS). Disappointingly, some children without bladder impairment showed a deterioration of bladder function after surgery, which critically influences the health-related quality of life. It was hypothesized that the DS might have a significant effect on bladder function and psychology.

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Objective: The aim of this study is to explore the inherent classification of social support among individuals residing in rural areas of China. Additionally, we aim to examine the attributes and variations in health literacy scores among patients with diabetes mellitus (DM) within diverse social support categories.

Design: Cross-sectional study.

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In order to reduce the cost of scaffolding usage in engineering projects as much as possible under the premise of safety and rationality, while avoiding the risk of leakage caused by holes left in the building structure by the scaffolding, a type of inclined tensioned steel cantilevered scaffolding is proposed based on the stress characteristics of traditional cantilevered scaffolding. Considering the actual construction characteristics, a comprehensive approach involving theoretical analysis, on-site field tests, and finite element methods is adopted to clarify the full-process design method of the inclined tensioned steel cantilevered scaffolding. Additionally, recommendations are provided for the practical engineering design and application of the inclined tensioned steel cantilevered scaffolding.

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As natural and biodegradable biopolymers, Polyhydroxyalkanoates (PHA) were synthetized by aerobic granules sludge (AGS) in a sequential batch reactor in this study. The effect of different COD concentrations on PHA accumulation and nutrients removal were investigated. At the same time, different pretreatment methods for PHA extraction, including NaClO pretreatment for extracellular polymeric substances (EPS) removal, NaCO pretreatment for EPS recovery, and grinding pretreatment to reduce particle size and augment the surface area available for interaction with the extraction solvent, were compared.

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Renal fibrosis is the major pathological changes of Chronic kidney disease (CKD). Piezo1, a mechanical sensitive ion channel, is implicated in organ fibrosis. However, the precise role of Piezo1 in CKD fibrosis is unknown.

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Objective: This study aims to develop and validate a predictive model that integrates clinical features, MRI radiomics, and nutritional-inflammatory biomarkers to forecast progression-free survival (PFS) in cervical cancer (CC) patients undergoing concurrent chemoradiotherapy (CCRT). The goal is to identify high-risk patients and guide personalized treatment.

Methods: We performed a retrospective analysis of 188 patients from two centers, divided into training (132) and validation (56) sets.

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Self-healing hydrogels have attracted significant attention in chronic diabetic wound healing due to their potential to minimize the risk of secondary infections caused by joint movement or dressing rupture. Herein, a multifunctional self-healing hydrogel mediated utilizing an enzyme-triggered cascade reaction based on dynamic imine bonds was designed. The hydrogel employs three enzymes: lysozyme (LYZ), glucose oxidase (GOx), and catalase (CAT), as building blocks.

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Article Synopsis
  • Ovarian tumors are categorized into four main types: epithelial, germ cell, sex cord-stromal, and metastatic, each having unique biological behaviors.
  • Ovarian lymphangioma is a rare benign tumor that is uncommon in the ovaries specifically, making it notable in medical literature.
  • The reported case involved a patient who underwent laparoscopic surgery after finding an ovarian mass, and she experienced a smooth recovery with no signs of recurrence post-operation.
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Tracheal stents can be used to quickly reconstruct the airway and relieve symptoms of dyspnea in patients with tracheal stenosis. However, existing tracheal stents lead to complications such as granulation tissue formation, difficulty in removal, persistent growth of malignant tumors, stent migration, and mucus plugging. In this article, we reviewed the main methods used to reduce complications associated with tracheal stent design.

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  • Familial hypercholesterolemia (FH) is a genetic disorder mainly caused by mutations in the LDLR gene, specifically identifying two pathogenic mutations: c.G1027A (p.Gly343Ser) and c.G1879A (p.Ala627Thr).
  • Whole exome sequencing was used to identify mutations in FH patients, followed by Sanger sequencing in their family members to analyze genetic correlations and evaluate LDLR expression using various cell assays.
  • Results showed p.Gly343Ser had normal protein localization, while p.Ala627Thr exhibited decreased expression and cytoplasmic localization, with bioinformatics indicating possible impacts on post-translational modifications affecting protein levels.
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  • This study investigates how proton pump inhibitors (PPIs) impact the saliva microbiota of laryngopharyngeal reflux (LPR) patients by analyzing saliva samples before and after an 8-week PPI regimen.
  • Results showed a significant change in both the diversity and composition of saliva microbiota post-PPI usage, highlighting a shift in bacterial populations.
  • Key findings indicate an increase in certain harmful bacteria and a decrease in beneficial bacteria, alongside changes in metabolic gene functions in the saliva microbiota after PPI treatment.
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Crossed high alcohol preferring (cHAP) mice have been selectively bred to consume considerable amounts of alcohol resulting in binge drinking. The dorsomedial striatum (DMS) is a brain region involved in goal-directed action selection, and dorsolateral striatum (DLS) is a brain region involved in habitual action selection. Alcohol use disorder (AUD) may involve a disruption in the balance between the DMS and DLS.

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  • The study evaluates the effectiveness of enterovirus A71 (EV-A71) vaccines in reducing hand, foot, and mouth disease (HFMD) cases among children under 5 in China, with analysis based on surveillance data and statistical models.
  • Findings show that between 2017 and 2018, vaccination led to a significant reduction in HFMD incidence, with a relative risk of 0.83, translating to about 298,000 fewer cases.
  • The effectiveness of the vaccine varied by region, was better in areas with higher vaccination coverage (above 20%), and decreased in more densely populated areas, highlighting the need for improved vaccination strategies.
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Objectives: The expression of serum free light chain (FLC) is abnormal in various diseases, but its role in lung cancer remains unclear. This study aims to investigate the expression and diagnostic value of serum FLC in lung cancer.

Methods: A total of 80 lung cancer patients treated at Xiangdong Hospital, Hunan Normal University from January to December 2021 were selected as the lung cancer group.

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Avian leukosis virus subgroup J (ALV-J), a member of the genus Alpharetrovirus, possesses a small genome and exploits a vast array of host factors during its replication cycle. To identify host factors required for ALV-J replication and potentially guide the development of key therapeutic targets for ALV-J prevention, we employed a chicken genome-wide CRISPR/Cas9 knockout library to screen host factors involved in ALV-J infection within DF-1 cells. This screening revealed 42 host factors critical for ALV-J infection.

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