Single-Channel Sleep EEG Classification Method Based on LSTM and Hidden Markov Model.

Background: The single-channel sleep EEG has the advantages of convenient collection, high-cost performance, and easy daily use, and it has been widely used in the classification of sleep stages.

Methods: This paper proposes a single-channel sleep EEG classification method based on long short-term memory and a hidden Markov model (LSTM-HMM). First, the single-channel EEG is decomposed using wavelet transform (WT), and multi-domain features are extracted from the component signals to characterize the EEG characteristics fully.

MDD brain network analysis based on EEG functional connectivity and graph theory.

Background: Existing studies have shown that the brain network of major depression disorder (MDD) has abnormal topologies. However, constructing reliable MDD brain networks is still an open problem.

New Method: This paper proposed a reliable MDD brain network construction method.

Effect of protein-polysaccharide hybrid gelator system on the material properties and 3D extrusion printability of mashed potatoes.

Mashed potatoes (MP) are famous as ready-to-eat products due to their excellent taste and texture. Problems such as complex injection occur when MP is used as a 3D printing material. To improve the smoothness of MP loading into a 3D syringe barrel and its 3D extrusion printability, the effects of the protein-polysaccharide hybrid gelator developed with different gelatin-B (GB, 2%, 4%, 6%) and κ-carrageenan (KG, 1%) on the rheology and 3D extrusion printability of MP were studied.

Paeonol alleviates ulcerative colitis in mice by increasing short-chain fatty acids derived from Clostridium butyricum.

Background: Increasing evidence suggests that repairing the damaged intestinal epithelial barrier and restoring its function is the key to solving the problem of prolonged ulcerative colitis. Previous studies have shown that paeonol (pae) can alleviate colitis by down-regulating inflammatory pathways. In addition, pae also has a certain effect on regulating intestinal flora.

EEG feature selection method based on maximum information coefficient and quantum particle swarm.

To reduce the dimensionality of EEG features and improve classification accuracy, we propose an improved hybrid feature selection method for EEG feature selection. First, MIC is used to remove irrelevant features and redundant features to reduce the search space of the second stage. QPSO is then used to optimize the feature in the second stage to obtain the optimal feature subset.

Synthesis and Reactivity of a Zinc Diazoalkyl Complex: [3+2] Cycloaddition Reaction with Carbon Monoxide.

This work reports the synthesis, characterization, and reactivity of the first example of a well-defined zinc α-diazoalkyl complex. Treatment of zinc(I)-zinc(I) bonded compound L Zn [L=CH C(2,6- Pr C H N)CHC(CH )(NCH CH PPh )] or zinc(II) hydride LZnH with trimethylsilyldiazomethane affords zinc diazoalkyl complex LZnC(N )SiMe . This complex liberates N in the presence of a nickel catalyst to form an α-zincated phosphorus ylide by reacting with the pendant phosphine.

Retrospective study of influencing factors on the outcomes of luteal phase stimulation in patients with dual stimulation.

Background: Dual/double stimulation (DS) is an ovarian stimulation strategy that has emerged in recent years; it is characterized by two rounds of ovarian stimulation and oocyte retrieval in the same menstrual cycle. DS can greatly shorten the time required to obtain valid embryos in assisted reproduction. For fertility preservation, DS can speed up oocyte storage process.

A Planar Nickelaspiropentane Complex with Magnesium-Based Metalloligands: Synthesis, Structure, and Synergistic Dihydrogen Activation.

The nature of transition-metal-olefin bonding has been explained by the Dewar-Chatt-Duncanson model within a continuum of two extremes, namely, a π-complex and a metallacyclopropane. The textbook rule suggests that a low-spin late-transition-metal-ethylene complex more likely forms a π-complex rather than a metallacyclopropane. Herein, we report a low-spin late-transition-metal--ethylene complex forming an unprecedented planar metalla--cyclopropane structure with magnesium-based metalloligands.

Hot extrusion 3D printing technologies based on starchy food: A review.

Three-dimensional (3D) printing is a new technique used to construct complex geometric forms for personalized nutrition and customization. With good rheological and gelling properties, starch materials have great potential in the 3D printed food industry. The successful printing of materials depends on various aspects, and current researches have focused on discussing the influence of the rheological properties of starch materials on printing, while the researches on the printing characteristics with other starch properties, material processing methods, printing process parameters are still insufficient.

Synthesis and Reactivity of Triangular Heterometallic Complexes Containing Zn-Zn Bond.

This work provides a facile access to a series of triangular [ZnM] (M = group 10 and 11 metals) clusters. Treatment of Zn-Zn-bonded compounds [Zn-Zn] ( = CHC(2,6-PrCHN)CHC(CH)(NCHCHPR); R = Ph, Pr) with zero-valent transition-metal reagents selectively afforded the corresponding triangular clusters [ZnM], where M = Ni(0), Pd(0), and Pt(0). Notably, the isoelectronic triangular clusters [ZnM], where M = Ag(I) and Cu(I), could also be obtained by reactions of [LZn-ZnL] with AgOTf and CuOTf, respectively.

Removal of PFASs from water by carbon-based composite photocatalysis with adsorption and catalytic properties: A review.

Per- and polyfluoroalkyl substances (PFASs) are a class of persistent organic pollutants widely distributed in aquatic environments. The adsorption and photocatalytic methods have been widely used to remove PFASs in water because of their respective advantages. Still, they have apparent defects when used alone.

Persistent Currents in Rings of Ultracold Fermionic Atoms.

We have produced persistent currents of ultracold fermionic atoms trapped in a ring, with lifetimes greater than 10 sec in the strongly interacting regime. These currents remain stable well into the BCS regime at sufficiently low temperature. We drive a circulating BCS superfluid into the normal phase and back by changing the interaction strength and find that the probability for quantized superflow to reappear is remarkably insensitive to the time spent in the normal phase and the minimum interaction strength.

Synthesis and reactivity of heterometallic complexes containing Mg- or Zn-metalloligands.

Heteronuclear metal complexes comprising main group metals and transition metals have attracted widespread attention from researchers due to their applications in stoichiometric and catalytic activation of small molecules with possible cooperative effects. Herein, the advances of heterometallic complexes containing Mg- or Zn-metalloligands over the past ten years are reviewed. They consist of two parts: (i) synthetic approaches to heterometallic complexes.

Nickel-catalyzed synthesis of Zn(I)-Zn(I) bonded compounds.

This work reports the first catalyzed synthesis of d-block metal-metal bonded complexes. The treatment of terminal zinc hydrides [LZnH] [L = CHC(2,6-PrCHN)CHC(CH)(N(CH)CHPR); = 1, 2; R = Ph, Pr] in the presence of 5 mol% Ni(CO)(PPh) afforded Zn(I)-Zn(I) bonded compounds [LZn] in high isolated yields with concomitant elimination of dihydrogen. Stoichiometric reactions, kinetic studies and DFT calculations were conducted to elucidate the reaction mechanism.

A review of responses of terrestrial organisms to perfluorinated compounds.

Perfluorinated compounds (PFCs) are a class of persistent organic pollutants with widespread distribution in the environment. Since the soil environment has become a significant sink for PFCs, the toxicological assessment about their potential effects on terrestrial organisms is necessary. This review compiles the toxicity researches of regular and emerging PFCs on classical terrestrial biota i.

Risk factors for disease severity in COVID-19 patients: A single-center retrospective study.

Background: The outbreak of coronavirus disease 2019 (COVID-19) has posed a huge threat to human health. However, little is known regarding the risk factors associated with COVID-19 severity. We aimed to explore early-stage disease risk factors associated with eventual disease severity.

Corticosteroid therapy for coronavirus disease 2019-related acute respiratory distress syndrome: a cohort study with propensity score analysis.

Background: The impact of corticosteroid therapy on outcomes of patients with coronavirus disease 2019 (COVID-19) is highly controversial. We aimed to compare the risk of death between COVID-19-related ARDS patients with corticosteroid treatment and those without.

Methods: In this single-center retrospective observational study, patients with ARDS caused by COVID-19 between January 20, 2020, and February 24, 2020, were enrolled.

Metagenomic analysis of soil microbial community under PFOA and PFOS stress.

Perfluorinated compounds (PFCs) contamination of soil has attracted global attention in recent years but influences of PFCs on microorganisms in the soil environment have not been fully described. In this study, the effects of perfluorooctane sulphonate (PFOS) and perfluoroctanoic acid (PFOA) on bacterial communities were determined by Illumina Miseq sequencing and Illumina Hiseq Xten. The stimulation of PFCs pollutants on soil bacterial richness and community diversity were observed.

Effect of perfluorooctanoic acid on microbial activity in wheat soil under different fertilization conditions.

Perfluorooctanoic acid (PFOA) is an emerging persistent organic pollutant which has been identified at significant levels in soils. Existed ecotoxicological studies have mainly employed earthworms to evaluate the toxicity of PFOA. However, little information do we know about the toxicity of PFOA regarding soil microorganisms.

The impact of laryngopharyngeal reflux disease on 95 hospitalized patients with COVID-19 in Wuhan, China: A retrospective study.

Studies have demonstrated that comorbidities, especially cardiovascular and endocrine diseases, correlated with poorer clinical outcomes. However, the impact of digestive system diseases has not been issued. The aim of this study is to determine the impact of laryngopharyngeal reflux disease (LPRD) on hospitalized patients with coronavirus disease 2019 (COVID-19).

Effects of Immersion Freezing on Ice Crystal Formation and the Protein Properties of Snakehead ().

This study aimed to evaluate the effect of immersion freezing (IF) at different temperatures on ice crystal formation and protein properties in fish muscle. Snakehead blocks were frozen by IF at -20, -30, and -40 °C, and conventional air freezing (AF) at -20 °C. The size of ice crystals in the frozen samples was evaluated using Image J software.

A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.

Background: No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV-2.

Methods: We conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxygen (Pao) to the fraction of inspired oxygen (Fio) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir-ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone.

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.

Importance: Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and has subsequently spread worldwide. Risk factors for the clinical outcomes of COVID-19 pneumonia have not yet been well delineated.

Objective: To describe the clinical characteristics and outcomes in patients with COVID-19 pneumonia who developed acute respiratory distress syndrome (ARDS) or died.

Investigation of the Interaction Mechanism of Perfluoroalkyl Carboxylic Acids with Human Serum Albumin by Spectroscopic Methods.

Perfluoroalkyl carboxylic acids (PFCAs) are some of the most significant pollutants in human serum, and are reported to be potentially toxic to humans. In this study, the binding mechanism of PFCAs with different carbon lengths to human serum albumin (HSA) was studied at the molecular level by means of fluorescence spectroscopy under simulated physiological conditions and molecular modeling. Fluorescence data indicate that PFCAs with a longer carbon chain have a stronger fluorescence quenching ability.