Effects of enzyme-inducing antiseizure medication on vitamin D dosing in adult veterans with epilepsy.

Background: The association of antiseizure medication (ASM) and bone density abnormalities has long been recognized; however, there remains a lack of consensus on efficacy and optimal vitamin D dosing in patients receiving enzyme inducing and non-inducing ASMs. The objective was to explore the relationship between ASMs and vitamin D supplementation requirements in a population of adult patients with epilepsy.

Methods: Patients with a diagnosis of epilepsy receiving supplemental vitamin D were included in this retrospective chart review.