Cysteine -acetylation is a post-translational modification involved in metabolic regulation.

Cysteine is a reactive amino acid central to the catalytic activities of many enzymes. It is also a common target of post-translational modifications (PTMs), such as palmitoylation. This longchain acyl PTM can modify cysteine residues and induce changes in protein subcellular localization.

Selenium-Based Catalytic Scavengers for Concurrent Scavenging of H S and Reactive Oxygen Species.

Hydrogen sulfide (H S) is an endogenous gasotransmitter that plays important roles in redox signaling. H S overproduction has been linked to a variety of disease states and therefore, H S-depleting agents, such as scavengers, are needed to understand the significance of H S-based therapy. It is known that elevated H S can induce oxidative stress with elevated reactive oxygen species (ROS) formation, such as in H S acute intoxication.

Intramolecular tetrazine-acryloyl cycloaddition: chemistry and applications.

An unprecedented intramolecular [4 + 2] tetrazine-olefin cycloaddition with α,β-unsaturated substrates was discovered. The reaction produces unique coumarin-dihydropyridazine heterocycles that exhibited strong fluorescence with large Stokes shifts and excellent photo- and pH-stability. This property can be used for reaction analysis.

Methods for Suppressing Hydrogen Sulfide in Biological Systems.

Hydrogen sulfide (HS) plays critical roles in redox biology, and its regulatory effects are tightly controlled by its cellular location and concentration. The imbalance of HS is believed to contribute to some pathological processes. Downregulation of HS requires chemical tools such as inhibitors of HS-producing enzymes and HS scavengers.