Publications by authors named "Yannick Throm"
Article Synopsis
- Scientists studied how aging affects inflammation in the intestines of mice by looking at different types of cells.
- They discovered that older intestinal stem cells change in a way that promotes inflammation, and this change can be passed on through cell cultures.
- The researchers also found that a specific signaling pathway (STAT1) plays a key role in how these inflammation-related genes are activated.
Treatment of myelodysplastic syndromes includes the administration of the hypomethylating agent decitabine. An early platelet response in decitabine-treated myelodysplastic syndrome patients is a predictor of overall survival. The effect of decitabine on megakaryocytes and the bone marrow, however, is understudied.
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