Rotenoids and Isoflavones from (Taub.) Mendonça & E.P. Souza and Their Biological Activities.

The phytochemical study of the ethanolic extract of the leaf of led to the isolation of five hitherto unreported compounds including two isoflavones (-), and three rotenoids (-), along with eight known isoflavonoid derivatives (-) and one pterocarpan derivative (). The structures of the new compounds and those of the known ones were established by the spectroscopic (1D and 2D NMR) and spectrometric (HRESIMS) techniques as well as a comparison of their spectroscopic data with those reported in the literature. The leaf extract, fractions, and isolated compounds were tested for their antibacterial effects against nine bacterial strains.

Antinociceptive and anti-inflammatory effects of the methanolic stem bark extract of Antrocaryon klaineanum Pierre (Anacardiaceae) in mice and rat.

Ethnopharmacological Relevance: Antrocaryon klaineanum is used by traditional healers to treat many disorders including pain and inflammatory diseases. This study aimed to evaluate the analgesic and antiinflammatory activities of methanol extract of A. klaineanum in mice and rats.

The structure of antrocarine E, an ergostane isolated from Antrocaryon klaineanum Pierre (Anacardiaceae).

Eight compounds were isolated from the stem bark of Antrocaryon klaineanum, and their structures determined by chemical and spectroscopic methods. Among these compounds, the ergostane-type antrocarine E (1a) is a new compound, although the structure had already been published by mismatching the spectroscopic data with those of 2. In this paper, we are reporting the valid spectroscopic values for antrocarine E and X-ray diffraction results.