Publications by authors named "Yannick Bazitama Munyeku"
Article Synopsis
- The study investigates the reliability of rapid diagnostic tests (RDTs) for malaria, specifically focusing on the detection of the PfHRP2 protein in Plasmodium falciparum, as deletions of this gene may lead to missed malaria cases.
- Blood samples from asymptomatic and symptomatic school-age children in Kinshasa, Democratic Republic of Congo, were collected and analyzed using microscopy and PCR to assess the accuracy of RDTs compared to these methods.
- The results indicated varying rates of detection, with RDTs showing 80-92% sensitivity compared to PCR and 60-77% compared to microscopy, while 4% of asymptomatic samples had deletions of the pfhrp2 gene, suggesting
Background: Malaria rapid diagnostic tests have become a primary and critical tool for malaria diagnosis in malaria-endemic countries where Plasmodium falciparum Histidine Rich Protein 2-based rapid diagnostic tests (PfHRP2-based RDTs) are widely used. However, in the last decade, the accuracy of PfHRP2-based RDTs has been challenged by the emergence of P. falciparum strains harbouring deletions of the P.
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