Using nomogram scores to predict the early regression of coronary artery aneurysms of Kawasaki disease.

Background: Coronary artery aneurysms have been considered the most serious complication of Kawasaki disease. However, some coronary artery aneurysms do regress. Therefore, the ability to predict the expected time of coronary artery aneurysm regression is critical.

Role of LAMA4 Gene in Regulating Extravillous Trophoblasts in Pathogenesis of Preeclampsia.

BACKGROUND Preeclampsia is a severe obstetric complication affecting the health of pregnant women. The aim of this study was to determine the effect of LAMA4 gene on extravillous trophoblasts (EVTs) in the pathogenesis of preeclampsia and its possible regulatory mechanism. MATERIAL AND METHODS HTR-8/SVneo cells were transfected with small-interfering ribonucleic acid (siRNA) targeting LAMA.