Publications by authors named "Yanni La"
Genetic diversity is an essential indicator that echoes the natural selection and environmental adaptation of a species. Isolated small populations are vulnerable to genetic drift, inbreeding, and limited gene flow; thus, assessing their genetic diversity is critical in conservation. In this study, we studied the genetic diversity of black-and-white snub-nosed monkeys () using neutral microsatellites and five adaptive major histocompatibility complex (MHC) genes.
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- - Mycobacterium abscessus causes severe infections and has dual resistance mechanisms to macrolide antibiotics like clarithromycin, making treatment challenging due to the presence of erm(41) and rrl gene mutations.
- - The study developed a real-time PCR assay that effectively detects both types of antibiotic resistance in M. abscessus, showing high correlation with traditional methods.
- - Findings indicated that real-time PCR is a more reliable method for identifying clarithromycin resistance, especially when dealing with mixed genotypes in samples, achieving 100% agreement with sequencing results in this study.