Publications by authors named "Yann-Suhan Senova"
Transcranial Direct Current Stimulation (tDCS) has shown potential in modulating cortical activity and treating depression. Despite its promise, variability in electrode montage configurations and electric field strength across studies has resulted in inconsistent outcomes. Traditional meta-analytic methods assessing the effect of tDCS in depression typically do not compare tDCS montage and the anatomical distribution of electric field, which is a major source of inter-experimental variability.
View Article and Find Full Text PDFArticle Synopsis
- Optogenetics has transformed neuroscience research in small animals, but its effectiveness in non-human primates (NHPs) has shown mixed results.
- * A centralized database has been created to help researchers track both successful and unsuccessful optogenetic experiments in primates, with contributions from 45 laboratories worldwide.
- * The database, available on the Open Science Framework, aims to enhance research by sharing over 1,000 injection experiments and offers insights to improve optogenetic methods in NHPs.*
Optogenetic neuromodulation techniques, which have emerged during the last 15 years, have considerably enhanced our ability to probe the functioning of neural circuits by allowing the excitation and inhibition of genetically-defined neuronal populations using light. Having gained tremendous popularity in the field of fundamental neuroscience, these techniques are now opening new therapeutic avenues. Optogenetic neuromodulation is a method of choice for studying the physiopathology of neurological and neuropsychiatric disorders in a range of animal models, and could accelerate the discovery of new therapeutic strategies.
View Article and Find Full Text PDF