Publications by authors named "Yanmin Xiao"
Article Synopsis
- Sepsis-induced myocardial injury (SIMI) is crucial in severe sepsis and septic shock, with METTL14 playing a key role in m6A RNA modification related to cardiac cell injury.
- LPS treatment leads to reduced cell viability and increased apoptosis and oxidative stress in human cardiomyocyte cells, with METTL14 and TRPM7 being upregulated.
- METTL14 enhances TRPM7 mRNA stability through m6A methylation; knockdown of METTL14 mitigates LPS-induced cardiac damage, suggesting a potential treatment target for septic cardiomyopathy.
Vitamin D Attenuates Airway Inflammation in Asthmatic Guinea Pigs Using Mammalian Target of Rapamycin-Mediated Autophagy.
J Interferon Cytokine Res
April 2022
The purpose of this experiment is to find out the function of Vitamin D (VD) in airway inflammation in asthmatic guinea pigs by regulating mammalian target of rapamycin (mTOR)-mediated autophagy. A total of 40 male guinea pigs were randomly assigned into the Con group, the ovalbumin (OVA)-sensitized group, the VD group, the VD + dimethyl sulfoxide group, and the VD + rapamycin (mTOR inhibitor) group. Then, serum from all groups was harvested for the measurement of immunoglobulin E (IgE), interleukin (IL)-4, and IL-5 levels.
View Article and Find Full Text PDFVitamin D has an effect on airway inflammation and Th17/Treg balance in asthmatic mice.
Kaohsiung J Med Sci
December 2021
Asthma is regarded as a chronic inflammation of the airway. Research has highlighted the significance of Vitamin D in asthma. This study explored the mechanism of vitamin D on asthma.
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