Sarcopenia adversely impacts clinical outcomes in patients undergoing pancreaticoduodenectomy: A systematic review and meta-analysis.

Background: Sarcopenia is a syndrome marked by a gradual and widespread reduction in skeletal muscle mass and strength, as well as a decline in functional ability, which is associated with malnutrition, hormonal changes, chronic inflammation, disturbance of intestinal flora, and exercise quality. Pancreatoduodenectomy is a commonly employed clinical intervention for conditions such as pancreatic head cancer, ampulla of Vater cancer, and cholangiocarcinoma, among others, with a notably high rate of postoperative complications. Sarcopenia is frequent in patients undergoing pancreatoduodenectomy.

Influence of heat treatment before and/or after high-pressure homogenization on the structure and emulsification properties of soybean protein isolate.

This study investigates the effects of heat treatment before high-pressure homogenization (HHPH) and heat treatment after high-pressure homogenization (HPHH) at different pressures (20, 60, and 100 MPa) on the structural and emulsification properties of soy protein isolate (SPI). The results indicate that HHPH treatment increases the surface hydrophobicity (H) of the SPI, reduces β-fold and irregular curls, leading to the formation of soluble aggregates, increased adsorbed protein content, and subsequent improvements in emulsification activity index (EAI) and emulsion stability index (ESI). In contrast, the HPHH treatment promoted the exchange of SH/SS bonds between protein molecules and facilitated the interaction of basic peptides and β-subunits, leading to larger particle sizes of the soluble aggregates compared to the HHPH-treated samples.

Short-Chain Fatty-Acid-Producing Micro-Organisms Regulate the Pancreatic FFA2-Akt/PI3K Signaling Pathway in a Diabetic Rat Model Affected by Pumpkin Oligosaccharides.

Herein, we applied the Illumina MiSeq pyrosequencing platform to amplify the V3-V4 hypervariable regions of the 16 S rRNA gene of the gut microbiota (GM) and a gas chromatograph-mass spectrometer to detect the metabolites after supplementation with pumpkin oligosaccharides (POSs) to determine the metabolic markers and mechanisms in rats with type 2 diabetes (T2D). The POSs alleviated glucolipid metabolism by decreasing the serum low-density lipoprotein (LDL), total cholesterol (TC), and glucose levels. These responses were supported by a shift in the gut microbiota, especially in the butyric-acid-producing communities.

Qishen Yiqi Dripping Pills for Cardiovascular Diseases: Effects and Mechanisms.

Qishen Yiqi Dripping Pills (QSYQ) is a compound of Chinese medicine, which has been used to treat coronary heart disease and cardiac dysfunction. Its natural components include astragaloside IV, flavonoids, danshensu, protocatechualdehyde, salvianolic acid B, salvianolic acid A, ginsenosides Rg1, ginsenosides Rb1, and essential oils, etc. It exerts effects of nourishing qi and promoting blood circulation to relieve pain.

Electrolytes with Micelle-Assisted Formation of Directional Ion Transport Channels for Aqueous Rechargeable Batteries with Impressive Performance.

Low-cost and ecofriendly electrolytes with suppressed water reactivity and raised ionic conductivity are desirable for aqueous rechargeable batteries because it is a dilemma to decrease the water reactivity and increase the ionic conductivity at the same time. In this paper, LiSO-NaSO-sodium dodecyl sulfate (LN-SDS)-based aqueous electrolytes are designed, where: (i) Na ions dissociated from SDS increase the charge carrier concentration, (ii) DS/SO anions and Li/Na cations are capable of trapping water molecules through hydrogen bonding and/or hydration, resulting in a lowered melting point, (iii) Li ions reduce the Krafft temperature of LN-SDS, (iv) Na and SO ions increase the low-temperature electrolyte ionic conductivity, and (v) SDS micelle clusters are orderly aggregated to form directional ion transport channels, enabling the formation of quasi-continuous ion flows without (r.t.

Syringaresinol attenuates sepsis-induced cardiac dysfunction by inhibiting inflammation and pyroptosis in mice.

The mortality of sepsis-induced cardiac dysfunction (SICD) is very high due to the complex pathophysiological mechanism. Syringaresinol (SYR) is a natural abstract which possesses anti-inflammatory property. The present study aims was to identify the protective impact of SYR on sepsis-induced cardiac dysfunction and investigate the specific mechanisms.

Lithobius (Monotarsobius) tetrasulcus sp. n., a new species of centipede from China (Lithobiomorpha, Lithobiidae).

Background: The myriapod fauna of China is still poorly known and very little attention has been paid to the study of Lithobiomorpha, with only 100 species and subspecies known from the country. Altogether, 11 species of subgenusMonotarsobius have been recorded from China, but only two of them have been reported from Hebei Province. Herein, a new species recently discovered in the Hebei Province, China, is described and illustrated.

A new species of Verhoeff, 1941 (Lithobiomorpha, Lithobiidae) from China with a key to species.

Background: The myriapod fauna of China is still poorly known and very little attention had been paid to the study of Lithobiomorpha, with only 100 species/subspecies hitherto known from the country, among which are only seven species of . Here we are describing a new species of the genus .

New Information: A new lithobiid species, sp.

() , a new species from eastern China (Lithobiomorpha, Lithobiidae).

Lithobius (Ezembius) varioporus (Lithobiomorpha, Lithobiidae), recently discovered from Longquanguan Town, Fuping County, Baoding City, Hebei Province, China, is described. Morphologically it resembles to Lithobius (Ezembius) laevidentata Pei, Ma, Hou, Zhu & Gai, 2015 from the Xinjiang Autonomous Region, but can be easily distinguished from the latter by the Tömösváry's organ, slightly smaller than the adjoining ocelli, no secondary sexual modifications on male tibia 14 and 15, posterior accessory spine of legs 14 and 15 present and the number of coxal pores varying considerably from three to eight. The main morphological characters of the known Chinese species of the subgenusEzembius Chamberlin, 1919 based on adult specimens are presented.

Retraction: Ethanol extract of Acanthopanax senticosus (Rupr. & Maxim.) Harms induces liver cancer cell apoptosis through inhibiting NF-κB.

[This retracts the article DOI: 10.21037/tcr.2020.

Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis.

Background: Periampullary tumors (PT) may rarely present as acute pancreatitis (AP) or acute recurrent pancreatitis (ARP). Unlike other cases of AP and ARP, these conditions necessitate pancreaticoduodenectomy (PD), and timely diagnosis is crucial. .

Morphological and Functional Characteristics of Animal Models of Myocardial Fibrosis Induced by Pressure Overload.

Myocardial fibrosis is characterized by excessive deposition of myocardial interstitial collagen, abnormal distribution, and excessive proliferation of fibroblasts. According to the researches in recent years, myocardial fibrosis, as the pathological basis of various cardiovascular diseases, has been proven to be a core determinant in ventricular remodeling. Pressure load is one of the causes of myocardial fibrosis.

Ethanol extract of (Rupr. & Maxim.) Harms induces liver cancer cell apoptosis through inhibiting NF-κB.

Background: (Rupr. & Maxim.) Harms, a traditional Chinese medicine, has been used to treat various diseases, including ischemic, heart diseases, hepatocellular carcinoma (HCC), hypertension and neurasthenia.

Extraction and Purification of Capsaicin from Capsicum Oleoresin Using a Combination of Tunable Aqueous Polymer-Phase Impregnated Resin (TAPPIR) Extraction and Chromatography Technology.

Capsaicin, which mainly comes from pepper, exhibits anticancer, antioxidant, and anti-obesity properties. This work aims to construct a comprehensive technology for the extraction and purification of capsaicin from capsicum oleoresin. The tunable aqueous polymer phase impregnated HZ816 resins were selected in extraction step.

Spleen-preserving distal pancreatectomy and lymphadenectomy for glucagonoma syndrome: A case report.

Rationale: Glucagonoma is a rare type of functional pancreatic neuroendocrine tumor that is characterized by distinctive clinical manifestations; among these, necrolytic migratory erythema represents the hallmark clinical sign of glucagonoma syndrome and is usually presented as the initial complaint of patients.

Patient Concerns: A 30-year-old male patient was admitted to our hospital with a complaint of diffuse erythematous ulcerating skin rash for more than 10 months. He also complained of hyperglycemia and a weight loss of 15 kg in those months.

Effects of C/EBPα overexpression on alveolar epithelial type II cell proliferation, apoptosis and surfactant protein-C expression after exposure to hyperoxia.

Background: This study aims to investigate the effects of CCAAT/enhancer binding protein alpha (C/EBPα) overexpression on cell proliferation, apoptosis and surfactant protein-C(SP-C) in alveolar epithelial type II (AEC II) cells after exposure to hyperoxia.

Methods: pcDNA3.1(+)-C/EBPα plasmid or air-empty vector were transfected into AEC II cells with or without hyperoxia.

MiRNA-124 inhibits the proliferation, migration and invasion of cancer cell in hepatocellular carcinoma by downregulating lncRNA-UCA1.

It has been reported that miRNA-124 inhibits hepatocellular carcinoma (HCC) progression, while lncRNA-UCA1 promotes HCC. The aim of this study is to find whether miRNA-124, as a tumor suppressor in HCC can inhibit lncRNA-UCA1 in HCC cell. Tumor tissues and adjacent healthy tissues were obtained from 66 patients diagnosed with HCC in Binzhou Medical University Hospital from January 2011 to January 2013.

Role of oxidative stress in cardiotoxicity of antineoplastic drugs.

Tumors and heart disease are two of the leading causes of human death. With the development of anti-cancer therapy, the survival rate of cancer patients has been significantly improved. But at the same time, the incidence of cardiovascular adverse events caused by cancer treatment has also been considerably increased, such as arrhythmia, left ventricular (LV) systolic and diastolic dysfunction, and even heart failure (HF), etc.

Correlation of miR-425-5p and IL-23 with pancreatic cancer.

The aim of this study was to detect the levels of miR-425-5p and IL-23 in tissues of pancreatic cancer patients and to explore their effects on pancreatic cancer. A retrospective analysis of 76 cases of pancreatic cancer tissue specimens and normal fresh tissue specimens at 50 mm adjacent to the corresponding cancer surgically resected in the first diagnosis was performed, in the Department of Radiotherapy of Traditional Chinese Medical Hospital of Huangdao District and Weifang Medical University Hospital from October 2015 to October 2016. RT-qPCR was used to detect miR-425-5p levels in pancreatic cancer and adjacent tissues, and ELISA to detect IL-23 levels in the tissues.

Lithobius (Ezembius) ternidentatus sp. n. (Lithobiomorpha, Lithobiidae), a new species from China.

Lithobius (Ezembius) ternidentatus (Lithobiomorpha, Lithobiidae), recently discovered from Wuyuezhai Mountain, Lingshou County, Shijiazhuang City, Hebei Province, China, is described. Morphologically it resembles L. (E.

Lithobius (Ezembius) tetraspinus, a new species of centipede from northwest China (Lithobiomorpha, Lithobiidae).

Lithobius (Ezembius) tetraspinus (Lithobiomorpha: Lithobiidae), recently discovered from Hami City, Xinjiang Autonomous Region, NW China, is described. Morphologically this species resembles L. (E.

, a new species of the genus Verhoeff, 1941 from China (Lithobiomorpha, Lithobiidae).

(Lithobiomorpha: Lithobiidae), recently discovered from Shandan County, Zhangye City, Province Gansu, Qinghai-Tibet Plateau, China, is described. Morphologically it resembles (Verhoeff, 1942), but can be easily distinguished from the latter by size of Tömösváry's organ's, the morphological characters of a protuberance on the dorsal end of the second article of the female gonopods; and obvious differences in the dorsal plectrotaxy of both the 14 and 15 legs. The main morphological characters and a key to the known Chinese species of genus based on adult specimens are presented.