Systematic review and meta-analysis of Tuberculosis and COVID-19 Co-infection: Prevalence, fatality, and treatment considerations.

Background: Tuberculosis (TB) and COVID-19 co-infection poses a significant global health challenge with increased fatality rates and adverse outcomes. However, the existing evidence on the epidemiology and treatment of TB-COVID co-infection remains limited.

Methods: This updated systematic review aimed to investigate the prevalence, fatality rates, and treatment outcomes of TB-COVID co-infection.

Impacts of climate warming and atmospheric deposition on recent shifts in chironomid communities in two alpine lakes, eastern China.

Climate warming and atmospheric deposition are altering alpine lake ecosystems at unprecedented rates, whereas their direct and indirect effects on primary consumer communities are unclear. This study presents sedimentary multi-proxy records including chironomids, diatoms, elements and stable isotopes of carbon and nitrogen in Pb-dated cores from two alpine lakes located above the timberline in the Taibai Mountain, eastern China. Before ∼2000 CE, chironomid communities were co-dominated by Heterotrissocladius marcidus-type and Micropsectra atrofasciata-type in the two lakes.

Asynchronous multitrophic level regime shifts show resilience to lake browning.

Lake browning is widespread due to increased supply of dissolved organic carbon under climate warming and nitrogen deposition. However, multitrophic level responses to lake browning are poorly understood. Our study aims to explore such responses across multitrophic levels based on sedimentary records of diatoms, chrysophyte stomatocysts and chironomids in a remote headwater lake in the Three Gorges Reservoir region, central China.

Effects of switching redox conditions on sediment phosphorus immobilization by calcium/aluminum composite capping: Performance, ecological safety and mechanisms.

There many materials were used in lake restoration to immobilize phosphorus (P) and reduce the effect of eutrophication. Among them, calcium/aluminum composite (CAC) showed a good capacity of P adsorption. However, a comprehensive of its performance, ecological safety, and the mechanism of P passivation in the aluminum-bound P (Al -P) dominated sediments under varying redox conditions remains incomplete.

Novel genetic variants linked to prelabor rupture of membranes among Chinese pregnant women.

Introduction: The etiology of prelabor rupture of membranes (PROM), either preterm or term PROM (PPROM or TPROM), remains largely unknown. This study aimed to investigate the association between maternal genetic variants (GVs) and PROM and further establish a GV-based prediction model for PROM.

Methods: In this case-cohort study (n = 1166), Chinese pregnant women with PPROM (n = 51), TPROM (n = 283) and controls (n = 832) were enrolled.

The therapeutic effects of attending a one-day outpatient service on patients with gestational diabetes and different pre-pregnancy body mass indices.

Purpose: This study investigated the effects of attending a one-day outpatient service on the outcomes of patients with gestational diabetes mellitus (GDM) and different pre-pregnancy body mass indices (BMIs).

Methods: The study recruited 311 pregnant women with GDM into a one-day outpatient service at The Fourth Hospital of Shijiazhuang from September 2019 to December 2021. They were randomly assigned to three groups, based on their pre-pregnancy BMI as follows: group A, BMI < 18.

Lipolysis and gestational diabetes mellitus onset: a case-cohort genome-wide association study in Chinese.

Background: Genetic knowledge of gestational diabetes mellitus (GDM) in Chinese women is quite limited. This study aimed to identify the risk factors and mechanism of GDM at the genetic level in a Chinese population.

Methods: We conducted a genome-wide association study (GWAS) based on single nucleotide polymorphism (SNP) array genotyping (ASA-CHIA Bead chip, Illumina) and a case-cohort study design.

Exploring and attributing change to fractional vegetation coverage in the middle and lower reaches of Hanjiang River Basin, China.

The middle and lower reaches of Hanjiang River Basin (MLHB), areas that have an important ecological function in China, have experienced great changes in the vegetation ecosystem driven by natural environmental change and human activity. Here, we explored the spatio-temporal dynamics of fractional vegetation coverage (FVC) and quantitatively analyzed its driving factors to advance current understanding of how the ecological environment has changed. Specifically, we used the dimidiate pixel model to calculate the FVC of the MLHB from 2001 to 2018 based on Moderate Resolution Imaging Spectroradiometer (MODIS) Enhanced Vegetation Index (EVI) data.

The effects of aqueous extract from watermelon (Citrullus lanatus) peel on the growth and physiological characteristics of Dolichospermum flos-aquae.

Nowadays, the increasing Dolichospermum (Anabaena) blooms pose a major threat to the aquatic environment and public health worldwide. The use of naturally derived chemicals from plants to control cyanobacteria blooms has recently received a tremendous amount of attention. This study investigates the possibility of transforming watermelon peel (WMP) into a biological resource to allelopathically inhibit Dolichospermum flos-aquae blooms.

MiR-140-5p exerts a protective function in pregnancy-induced hypertension via mediating TGF-β/Smad signaling pathway.

Animal experiments showed that PIH rats had increased mean arterial pressure (MAP), systolic blood pressure (SBP), and diastolic blood pressure (DBP), but decreased litter size, number of viable fetuses, fetal weight, and placental weight. The higher Flt-1 and lower VEGF was observed in PIH rats with elevated TNF-α and IL-6 levels and decreased IL-10 levels. Treatment with agomiR-140-5p improved regarding the above indicators.

Influence of one-day diabetes mellitus clinic management on blood glucose control and prognosis in patients with gestational diabetes mellitus.

Objective: To explore the influence of the one-day diabetes mellitus (DM) clinic management model on blood glucose control and prognosis in patients with gestational diabetes mellitus (GDM).

Methods: A total of 930 patients diagnosed with GDM by oral glucose tolerance test screening at 24-28 weeks of gestation were selected from those who underwent outpatient prenatal checkups at our hospital and were randomly divided into one-day DM clinic group ( = 509) and control group ( = 421). A one-day DM clinic intervention was conducted in the one-day DM clinic group, and individualized dietary interventions and exercise instruction were given in the control group.

Efficacy of carboprost tromethamine combined with leonurus japonicus for prevention of postpartum hemorrhage in high-risk pregnant women: A protocol for systematic review and meta-analysis.

Background: No well-designed and systematic evaluation of the efficacy and safety of leonurus japonicus injection (LJI) in combination with carboprost tromethamine has been found. Therefore, we undertook a meta-analysis to assess the efficacy and safety of carboprost tromethamine combined with LJI for the prevention of postpartum hemorrhage in high-risk pregnant women to provide new evidence-based medical evidence for clinical treatment.

Methods: This systematic review and meta-analysis would be performed according to Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines.

The Impact of the One-Day Clinic Diabetes Mellitus Management Model on Perinatal Outcomes in Patients with Gestational Diabetes Mellitus.

Objective: The aim of the present study was to explore the impact of the one-day clinic diabetes mellitus (DM) management model on perinatal outcomes in patients with gestational diabetes mellitus (GDM).

Methods: A total of 995 patients who underwent prenatal checkups at our hospital and were diagnosed with GDM by oral glucose tolerance test (OGTT) screening at 24-28 weeks of gestational age were enrolled between December 2018 and August 2020. The patients were randomly divided into a study group (541 cases) and a control group (454 cases).

Regime shifts in shallow lake ecosystems along an urban-rural gradient in central China.

Due to differential exploitation pressure, ecosystems along the urban to rural gradients often exhibit different status in ecological structure and function. This can be challenging for lake restoration, given the relative strengths, magnitudes and speed of the exploitation. In this paper, we reconstructed the ecological changes over the past century and identified the regime shifts based on subfossil aquatic biota (chironomid records) in three shallow lakes (Shahu, Yanxi and Futou Lake) along an urban-rural gradient in the Yangtze floodplain, China.

The diagnostic value and regulatory mechanism of miR-200a targeting in pregnancy-induced hypertension.

Objective: To investigate the diagnostic value and regulatory mechanism of miR-200a targeting ZEB1 in pregnancy-induced hypertension (PIH).

Methods: The expression of miR-200a and ZEB1 was detected in the placenta of PIH patients, and then the human trophoblastic cell line JEG-3 was transfected and divided into different groups: control group, NC group, ZEB1 siRNA group, miR-200a inhibitor group and miR-200a inhibitor group + ZEB1 siRNA group. After transfection, cell proliferation and migration/invasion were evaluated byMTT and Transwell assays, respectively, whereas apoptosis was assessed byflow cytometry.

A 12-hour comprehensive nutrition care benefits blood glucose level and weight gain and improves outcomes in pregnant women with gestational diabetes mellitus.

Background: Gestational diabetes mellitus (GDM) is associated with adverse outcomes and neonatal complications. Its prevalence has been rapidly increasing over the last decade; it is estimated that one in six pregnant women are diagnosed with GDM. Thus, an effective management approach is necessary for women with GDM.

Effects of climate warming and nitrogen deposition on subtropical montane ponds (central China) over the last two centuries: Evidence from subfossil chironomids.

Many remote montane ecosystems are experiencing biogeochemical changes driven by warming climate and atmospheric pollution. Compared with circumpolar and temperate lakes, the responses of subtropical montane lakes to these external stressors have been less investigated. Here we present sedimentary multi-proxies records (i.

Diatom-based water-table reconstruction in Sphagnum peatlands of northeastern China.

Peatlands are important ecosystems for biodiversity conservation, global carbon cycling and water storage. Hydrological changes due to climate variability have accelerated the degradation of global and regional ecosystem services of peatlands. Diatoms are important producers and bioindicators in wetlands, but comprehensive diatom-based inference models for palaeoenvironmental reconstruction in peatlands are scarce.

Roles of miR-210 in the pathogenesis of pre-eclampsia.

Introduction: This study aimed to explore the bio-function of miR-210 in the pathogenesis of pre-eclampsia and provide new insights into the diagnosis and treatment of pre-eclampsia.

Material And Methods: A JAR cell line cultured in standard or hypoxic conditions was used in this study. Expression levels of miR-210 and PTPN2 were determined using real-time polymerase chain reaction (RT-PCR).

Effects of dam construction and increasing pollutants on the ecohydrological evolution of a shallow freshwater lake in the Yangtze floodplain.

Large river-floodplain systems which provide a variety of societal, economic and biological benefits are undergoing extensive and intensive human disturbance. However, floodplain lakes responses to multiple stressors are poorly understood. The Yangtze River and its floodplain which provide water and food resources for more than 300 million people are an important region in China.

TCF7L2, CAPN10 polymorphisms are associated with gestational diabetes mellitus (GDM) risks: a meta-analysis.

Several polymorphisms have been identified in transcription factor 7-like 2 (TCF7L2), and calpain-10 (CAPN10) genes. Controversial conclusions for the genetic relationship between these polymorphisms and gestational diabetes mellitus (GDM) risks were obtained. Our study aims at assessing whether these polymorphisms are associated with GDM susceptibility via a meta-analysis.

Variations in diatom communities at genus and species levels in peatlands (central China) linked to microhabitats and environmental factors.

Peatlands are a specialized type of organic wetlands, fulfilling essential roles as global carbon sinks, headwaters of rivers and biodiversity hotspots. Despite their importance, peatlands are being lost at an alarming rate due to human disturbance and climatic variability. Both the scientific and regulatory communities have focused considerable attention on developing tools for assessing environmental changes in peatlands.

One century sedimentary record of lead and zinc pollution in Yangzong Lake, a highland lake in southwestern China.

Reconstruction of trace metal pollution histories and sources may help us to regulate current pollutant discharge. This is especially important for the highland lakes in southwestern China, which are facing trace metals pollution. We present sedimentary records of 11 metals accumulated in Yangzong Lake since the 1870's, a highland lake in southwestern China.