Ribophorin II promotes the epithelial-mesenchymal transition and aerobic glycolysis of laryngeal squamous cell carcinoma via regulating reactive oxygen species-mediated Phosphatidylinositol-3-Kinase/Protein Kinase B activation.

Ribophorin II (RPN2), a part of an N-oligosaccharyl transferase complex, plays vital roles in the development of multiple cancers. Nevertheless, its biological role in laryngeal squamous cell carcinoma (LSCC) remains unclear. The RPN2 expression levels in LSCC tissues and cell lines (AMC-HN-8 and TU212) were measured using real-time PCR, immunohistochemistry, or Western blot.

Reduction of blurring in broadband volume holographic imaging using a deconvolution method.

Volume holographic imaging (VHI) is a promising biomedical imaging tool that can simultaneously provide multi-depth or multispectral information. When a VHI system is probed with a broadband source, the intensity spreads in the horizontal direction, causing degradation of the image contrast. We theoretically analyzed the reason of the horizontal intensity spread, and the analysis was validated by the simulation and experimental results of the broadband impulse response of the VHI system.

Nonlinear greedy sparsity-constrained algorithm for direct reconstruction of fluorescence molecular lifetime tomography.

In order to improve the spatial resolution of time-domain (TD) fluorescence molecular lifetime tomography (FMLT), an accelerated nonlinear orthogonal matching pursuit (ANOMP) algorithm is proposed. As a kind of nonlinear greedy sparsity-constrained methods, ANOMP can find an approximate solution of L0 minimization problem. ANOMP consists of two parts, i.

In vivo simultaneous multispectral fluorescence imaging with spectral multiplexed volume holographic imaging system.

A simultaneous multispectral fluorescence imaging system incorporating multiplexed volume holographic grating (VHG) is developed to acquire multispectral images of an object in one shot. With the multiplexed VHG, the imaging system can provide the distribution and spectral characteristics of multiple fluorophores in the scene. The implementation and performance of the simultaneous multispectral imaging system are presented.